6LZJ
| Aquifex aeolicus MutL ATPase domain complexed with AMPPCP | 分子名称: | DNA mismatch repair protein MutL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Fukui, K, Izuhara, K, Yano, T. | 登録日 | 2020-02-19 | 公開日 | 2020-07-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.72835565 Å) | 主引用文献 | A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL. J.Biol.Chem., 295, 2020
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6LZK
| Aquifex aeolicus MutL ATPase domain with K252N mutation | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA mismatch repair protein MutL, SODIUM ION | 著者 | Fukui, K, Izuhara, K, Yano, T. | 登録日 | 2020-02-19 | 公開日 | 2020-07-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.15949631 Å) | 主引用文献 | A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL. J.Biol.Chem., 295, 2020
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6LZI
| Aquifex aeolicus MutL ATPase domain complexed with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA mismatch repair protein MutL, ... | 著者 | Fukui, K, Izuhara, K, Yano, T. | 登録日 | 2020-02-19 | 公開日 | 2020-07-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.69105685 Å) | 主引用文献 | A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL. J.Biol.Chem., 295, 2020
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5B42
| Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL. | 分子名称: | CADMIUM ION, DI(HYDROXYETHYL)ETHER, DNA mismatch repair protein MutL | 著者 | Fukui, K, Baba, S, Kumasaka, T, Yano, T. | 登録日 | 2016-03-30 | 公開日 | 2016-07-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural Features and Functional Dependency on beta-Clamp Define Distinct Subfamilies of Bacterial Mismatch Repair Endonuclease MutL J.Biol.Chem., 291, 2016
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7VUF
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7VUK
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8H1F
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8H1G
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8H1E
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5Z42
| Aquifex aeolicus MutL endonuclease domain with three zinc ions. | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, DNA mismatch repair protein MutL, ... | 著者 | Fukui, K, Yano, T. | 登録日 | 2018-01-10 | 公開日 | 2018-04-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Multiple zinc ions maintain the open conformation of the catalytic site in the DNA mismatch repair endonuclease MutL from Aquifex aeolicus FEBS Lett., 592, 2018
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5X9Y
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5Z41
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2ZQE
| Crystal structure of the Smr domain of Thermus thermophilus MutS2 | 分子名称: | MutS2 protein | 著者 | Fukui, K, Kitamura, Y, Nakagawa, N, Masui, R, Kuramitsu, S. | 登録日 | 2008-08-08 | 公開日 | 2008-09-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of MutS2 endonuclease domain and the mechanism of homologous recombination suppression J.Biol.Chem., 283, 2008
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4U4P
| Crystal structure of the human condensin SMC hinge domain heterodimer with short coiled coils | 分子名称: | Structural maintenance of chromosomes protein 2, Structural maintenance of chromosomes protein 4 | 著者 | Uchiyama, S, Kawahara, K, Hosokawa, Y, Fukakusa, S, Oki, H, Nakamura, S, Noda, M, Takino, R, Miyahara, Y, Maruno, T, Kobayashi, Y, Ohkubo, T, Fukui, K. | 登録日 | 2014-07-24 | 公開日 | 2015-08-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural basis for dimer information and DNA recognition of human SMC proteins to be published
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5H45
| Crystal structure of the C-terminal Lon protease-like domain of Thermus thermophilus RadA/Sms | 分子名称: | DNA repair protein RadA | 著者 | Inoue, M, Fukui, K, Fujii, Y, Nakagawa, N, Yano, T, Kuramitsu, S, Masui, R. | 登録日 | 2016-10-30 | 公開日 | 2017-05-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Lon protease-like domain in the bacterial RecA paralog RadA is required for DNA binding and repair. J. Biol. Chem., 292, 2017
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6KBP
| Crystal structure of human D-amino acid oxidase mutant (P219L) complexed with benzoate | 分子名称: | ACETATE ION, BENZOIC ACID, D-amino-acid oxidase, ... | 著者 | Rachadech, W, Kato, Y, Maita, N, Fukui, K. | 登録日 | 2019-06-26 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure of human D-amino acid oxidase mutant (P219L) complexed with benzoate To Be Published
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7ED6
| Crystal structure of Thermus thermophilus FakA ATP-binding domain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable kinase | 著者 | Nakatani, M, Nakahara, S, Fukui, K, Murakawa, T, Masui, R. | 登録日 | 2021-03-15 | 公開日 | 2022-03-16 | 最終更新日 | 2023-01-11 | 実験手法 | X-RAY DIFFRACTION (1.92850327 Å) | 主引用文献 | Crystal structure of a nucleotide-binding domain of fatty acid kinase FakA from Thermus thermophilus HB8. J.Struct.Biol., 214, 2022
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7ED9
| Crystal structure of selenomethionine-labeled Thermus thermophilus FakA ATP-binding domain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable kinase | 著者 | Nakatani, M, Nakahara, S, Fukui, K, Murakawa, T, Masui, R. | 登録日 | 2021-03-15 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.01764154 Å) | 主引用文献 | Crystal structure of a nucleotide-binding domain of fatty acid kinase FakA from Thermus thermophilus HB8. J.Struct.Biol., 214, 2022
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3WJ4
| Crystal structure of PPARgamma ligand binding domain in complex with tributyltin | 分子名称: | Peroxisome proliferator-activated receptor gamma, tributylstannanyl | 著者 | Harada, S, Hiromori, Y, Fukakusa, S, Kawahara, K, Nakamura, S, Noda, M, Uchiyama, S, Fukui, K, Nishikawa, J, Nagase, H, Kobayashi, Y, Ohkubo, T, Yoshida, T, Nakanishi, T. | 登録日 | 2013-10-04 | 公開日 | 2014-10-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds To be Published
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3WJ5
| Crystal structure of PPARgamma ligand binding domain in complex with triphenyltin | 分子名称: | Peroxisome proliferator-activated receptor gamma, triphenylstannanyl | 著者 | Harada, S, Hiromori, Y, Fukakusa, S, Kawahara, K, Nakamura, S, Noda, M, Uchiyama, S, Fukui, K, Nishikawa, J, Nagase, H, Kobayashi, Y, Ohkubo, T, Yoshida, T, Nakanishi, T. | 登録日 | 2013-10-04 | 公開日 | 2014-10-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds To be Published
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5YTQ
| Crystal Structure of TTHA0139 L34A with Lanthanum from Thermus thermophilus HB8 | 分子名称: | LANTHANUM (III) ION, TTHA0139 | 著者 | Takao, K, Inoue, M, Fukui, K, Yano, T, Masui, R. | 登録日 | 2017-11-19 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | 主引用文献 | Crystal Structure of TTHA0139 L34A with Lanthanum from Thermus thermophilus HB8 To Be Published
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5ZJ9
| human D-amino acid oxidase complexed with 5-chlorothiophene-3-carboxylic acid | 分子名称: | 5-chloro thiophene-3-carboxylic acid, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Kato, Y, Hin, N, Maita, N, Thomas, A.G, Kurosawa, S, Rojas, C, Yorita, K, Slusher, B.S, Fukui, K, Tsukamoto, T. | 登録日 | 2018-03-19 | 公開日 | 2018-10-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids Eur J Med Chem, 159, 2018
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5ZJA
| human D-amino acid oxidase complexed with 5-chlorothiophene-2-carboxylic acid | 分子名称: | 5-chloro thiophene-2-carboxylic acid, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Kato, Y, Hin, N, Maita, N, Thomas, A.G, Kurosawa, S, Rojas, C, Yorita, K, Slusher, B.S, Fukui, K, Tsukamoto, T. | 登録日 | 2018-03-19 | 公開日 | 2018-10-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids Eur J Med Chem, 159, 2018
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5XE9
| Crystal Structure of the Complex of the Peptidase Domain of Streptococcus mutans ComA with a Small Molecule Inhibitor. | 分子名称: | Putative ABC transporter, ATP-binding protein ComA, [(1~{S},2~{R},4~{S},5~{R})-5-[5-(4-methoxyphenyl)-2-methyl-pyrazol-3-yl]-1-azabicyclo[2.2.2]octan-2-yl]methyl ~{N}-propylcarbamate | 著者 | Ishii, S, Fukui, K, Yokoshima, S, Kumagai, K, Beniyama, Y, Kodama, T, Fukuyama, T, Okabe, T, Nagano, T, Kojima, H, Yano, T. | 登録日 | 2017-04-03 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.101 Å) | 主引用文献 | High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway Sci Rep, 7, 2017
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3A4U
| Crystal structure of MCFD2 in complex with carbohydrate recognition domain of ERGIC-53 | 分子名称: | CALCIUM ION, GLYCEROL, Multiple coagulation factor deficiency protein 2, ... | 著者 | Nishio, M, Kamiya, Y, Mizushima, T, Wakatsuki, S, Sasakawa, H, Yamamoto, K, Uchiyama, S, Noda, M, McKay, A.R, Fukui, K, Hauri, H.P, Kato, K. | 登録日 | 2009-07-17 | 公開日 | 2010-01-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency. Proc.Natl.Acad.Sci.USA, 107, 2010
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