7XEL
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![BU of 7xel by Molmil](/molmil-images/mine/7xel) | SufS soaked with D-penicillamine | Descriptor: | 1,2-ETHANEDIOL, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-03-31 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine to be published
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5ZS9
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![BU of 5zs9 by Molmil](/molmil-images/mine/5zs9) | |
5ZSR
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![BU of 5zsr by Molmil](/molmil-images/mine/5zsr) | |
5ZST
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![BU of 5zst by Molmil](/molmil-images/mine/5zst) | |
5ZSQ
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![BU of 5zsq by Molmil](/molmil-images/mine/5zsq) | |
5ZSK
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![BU of 5zsk by Molmil](/molmil-images/mine/5zsk) | |
5ZSP
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![BU of 5zsp by Molmil](/molmil-images/mine/5zsp) | NifS from Hydrogenimonas thermophila | Descriptor: | Cysteine desulfurase | Authors: | Nakamura, R, Fujishiro, T, Takahashi, Y. | Deposit date: | 2018-04-29 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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5ZSO
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![BU of 5zso by Molmil](/molmil-images/mine/5zso) | SufS from Bacillus subtilis, soaked with L-cysteine for 90 sec | Descriptor: | Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | Authors: | Nakamura, R, Fujishiro, T, Takahashi, Y. | Deposit date: | 2018-04-29 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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6KG1
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![BU of 6kg1 by Molmil](/molmil-images/mine/6kg1) | NifS from Helicobacter pylori, soaked with L-cysteine for 180 sec | Descriptor: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, CHLORIDE ION, Cysteine desulfurase IscS, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2019-07-09 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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6KFZ
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![BU of 6kfz by Molmil](/molmil-images/mine/6kfz) | SufS from Bacillus subtilis, soaked with L-cysteine for 90 sec at 1.96 angstrom resolution | Descriptor: | Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2019-07-09 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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7CEP
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![BU of 7cep by Molmil](/molmil-images/mine/7cep) | Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS from Bacillus subtilis | Descriptor: | (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nakamura, R, Yasuhiro, T, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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6KG0
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![BU of 6kg0 by Molmil](/molmil-images/mine/6kg0) | NifS from Helicobacter pylori, soaked with L-cysteine for 118 sec | Descriptor: | CHLORIDE ION, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2019-07-09 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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6KFY
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![BU of 6kfy by Molmil](/molmil-images/mine/6kfy) | |
7C8M
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![BU of 7c8m by Molmil](/molmil-images/mine/7c8m) | Crystal structure of IscU wild-type | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, Nitrogen-fixing NifU domain protein | Authors: | Kunichika, K, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-03 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The Structure of the Dimeric State of IscU Harboring Two Adjacent [2Fe-2S] Clusters Provides Mechanistic Insights into Cluster Conversion to [4Fe-4S]. Biochemistry, 60, 2021
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7C8N
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![BU of 7c8n by Molmil](/molmil-images/mine/7c8n) | Crystal structure of IscU H106A variant | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, Nitrogen-fixing NifU domain protein | Authors: | Kunichika, K, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-03 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Structure of the Dimeric State of IscU Harboring Two Adjacent [2Fe-2S] Clusters Provides Mechanistic Insights into Cluster Conversion to [4Fe-4S]. Biochemistry, 60, 2021
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7C8O
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7CET
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![BU of 7cet by Molmil](/molmil-images/mine/7cet) | Crystal structure of D-cycloserine-bound form of cysteine desulfurase NifS from Helicobacter pylori | Descriptor: | (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Cysteine desulfurase IscS, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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7CEQ
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7CER
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![BU of 7cer by Molmil](/molmil-images/mine/7cer) | Crystal structure of D-cycloserine-bound form of cysteine desulfurase SufS H121A from Bacillus subtilis | Descriptor: | Cysteine desulfurase SufS, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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7CEU
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![BU of 7ceu by Molmil](/molmil-images/mine/7ceu) | Crystal structure of L-cycloserine-bound form of cysteine desulfurase NifS from Helicobacter pylori | Descriptor: | (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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7CES
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![BU of 7ces by Molmil](/molmil-images/mine/7ces) | Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS H121A from Bacillus subtilis | Descriptor: | (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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7CEO
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![BU of 7ceo by Molmil](/molmil-images/mine/7ceo) | |
7CNV
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![BU of 7cnv by Molmil](/molmil-images/mine/7cnv) | |
7E6A
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![BU of 7e6a by Molmil](/molmil-images/mine/7e6a) | Crystal structure of cysteine desulfurase SufS C361A from Bacillus subtilis | Descriptor: | 1,2-ETHANEDIOL, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2021-02-22 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 289, 2022
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7E6E
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![BU of 7e6e by Molmil](/molmil-images/mine/7e6e) | Crystal structure of PMP-bound form of cysteine desulfurase SufS R376A from Bacillus subtilis in D-cycloserine-inhibition | Descriptor: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2021-02-22 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 289, 2022
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