5AMS
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1U9N
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![BU of 1u9n by Molmil](/molmil-images/mine/1u9n) | Crystal structure of the transcriptional regulator EthR in a ligand bound conformation opens therapeutic perspectives against tuberculosis and leprosy | 分子名称: | HEXADECYL OCTANOATE, Transcriptional repressor EthR | 著者 | Frenois, F, Engohang-Ndong, J, Locht, C, Baulard, A.R, Villeret, V. | 登録日 | 2004-08-10 | 公開日 | 2004-11-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of EthR in a Ligand Bound Conformation Reveals Therapeutic Perspectives against Tuberculosis Mol.Cell, 16, 2004
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1U9O
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![BU of 1u9o by Molmil](/molmil-images/mine/1u9o) | Crystal structure of the transcriptional regulator EthR in a ligand bound conformation | 分子名称: | HEXADECYL OCTANOATE, Transcriptional repressor EthR | 著者 | Frenois, F, Engohang-Ndong, J, Locht, C, Baulard, A.R, Villeret, V. | 登録日 | 2004-08-10 | 公開日 | 2004-11-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of EthR in a Ligand Bound Conformation Reveals Therapeutic Perspectives against Tuberculosis Mol.Cell, 16, 2004
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3G1M
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![BU of 3g1m by Molmil](/molmil-images/mine/3g1m) | EthR from Mycobacterium tuberculosis in complex with compound BDM31381 | 分子名称: | 1-(thiophen-2-ylacetyl)-4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine, TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR | 著者 | Willand, N, Dirie, B, Carette, X, Bifani, P, Singhal, A, Desroses, M, Leroux, F, Willery, E, Mathys, V, Deprez-Poulain, R, Delcroix, G, Frenois, F, Aumercier, M, Locht, C, Villeret, V, Deprez, B, Baulard, A.R. | 登録日 | 2009-01-30 | 公開日 | 2009-07-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Synthetic EthR inhibitors boost antituberculous activity of ethionamide. Nat.Med. (N.Y.), 15, 2009
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3G1O
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![BU of 3g1o by Molmil](/molmil-images/mine/3g1o) | EthR from Mycobacterium tuberculosis in complex with compound BDM14500 | 分子名称: | TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR, tert-butyl 4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate | 著者 | Willand, N, Dirie, B, Carette, X, Bifani, P, Singhal, A, Desroses, M, Leroux, F, Willery, E, Mathys, V, Deprez-Poulain, R, Delcroix, G, Frenois, F, Aumercier, M, Locht, C, Villeret, V, Deprez, B, Baulard, A.R. | 登録日 | 2009-01-30 | 公開日 | 2009-07-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Synthetic EthR inhibitors boost antituberculous activity of ethionamide. NAT.MED. (N.Y.), 15, 2009
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3G1L
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![BU of 3g1l by Molmil](/molmil-images/mine/3g1l) | EthR from Mycobacterium tuberculosis in complex with compound BDM14744 | 分子名称: | 3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole, TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR | 著者 | Willand, N, Dirie, B, Carette, X, Bifani, P, Singhal, A, Desroses, M, Leroux, F, Willery, E, Mathys, V, Deprez-Poulain, R, Delcroix, G, Frenois, F, Aumercier, M, Locht, C, Villeret, V, Deprez, B, Baulard, A.R. | 登録日 | 2009-01-30 | 公開日 | 2009-07-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Synthetic EthR inhibitors boost antituberculous activity of ethionamide. Nat.Med. (N.Y.), 15, 2009
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1H8Z
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![BU of 1h8z by Molmil](/molmil-images/mine/1h8z) | Crystal structure of the class D beta-lactamase OXA-13 | 分子名称: | BETA-LACTAMASE, SULFATE ION | 著者 | Pernot, L, Frenois, F, Rybkine, T, L'Hermite, G, Petrella, S, Delettre, J, Jarlier, V, Collatz, E, Sougakoff, W. | 登録日 | 2001-02-17 | 公開日 | 2001-07-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem J.Mol.Biol., 310, 2001
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1H8Y
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![BU of 1h8y by Molmil](/molmil-images/mine/1h8y) | Crystal structure of the class D beta-lactamase OXA-13 in complex with meropenem | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, BETA-LACTAMASE, SULFATE ION | 著者 | Pernot, L, Frenois, F, Rybkine, T, L'Hermite, G, Petrella, S, Delettre, J, Jarlier, V, Collatz, E, Sougakoff, W. | 登録日 | 2001-02-17 | 公開日 | 2001-07-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem J.Mol.Biol., 310, 2001
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3QPL
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![BU of 3qpl by Molmil](/molmil-images/mine/3qpl) | G106W mutant of EthR from Mycobacterium tuberculosis | 分子名称: | HTH-type transcriptional regulator EthR | 著者 | Carette, X, Willery, E, Hoos, S, Lecat-Guillet, N, Frenois, F, Dirie, B, Villeret, V, England, P, Deprez, B, Locht, C, Willand, N, Baulard, A. | 登録日 | 2011-02-14 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic Acids Res., 40, 2012
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