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PDB: 115 件
8DAN
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BU of 8dan by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein, ...
著者Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2022-06-13
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (4.74 Å)
主引用文献Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion
To Be Published
8DWX
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BU of 8dwx by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.C01 (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.C01 heavy chain, 506.C01 light chain, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2022-08-02
公開日2023-05-31
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWW
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BU of 8dww by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.A08 (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.A08 heavy chain, 506.A08 light chain, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2022-08-02
公開日2023-05-31
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWY
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BU of 8dwy by Molmil
Chikungunya VLP in complex with neutralizing Fab CHK-265 (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHK-265 heavy chain, CHK-265 light chain, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2022-08-02
公開日2023-05-31
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
7MKM
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BU of 7mkm by Molmil
SARS-CoV-2 Spike RBD in complex with neutralizing Fab SARS2-38 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-38 Fv heavy chain, SARS2-38 Fv light chain, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-04-24
公開日2021-05-12
最終更新日2021-12-01
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
Immunity, 54, 2021
7MKL
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BU of 7mkl by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-38 (three down conformation)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-38 Fv heavy chain, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-04-24
公開日2021-05-12
最終更新日2021-12-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
Immunity, 54, 2021
8EWF
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BU of 8ewf by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chimeric MXRA8 receptor: D1 from Duck MXRA8 and D2 from Mouse MXRA8, E1 envelope protein, ...
著者Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2022-10-22
公開日2023-10-25
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion
To Be Published
1XAU
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BU of 1xau by Molmil
STRUCTURE OF THE BTLA ECTODOMAIN
分子名称: B- and T-lymphocyte attenuator, CADMIUM ION
著者Nelson, C.A, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
登録日2004-08-26
公開日2004-10-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator.
J.Immunol., 180, 2008
6V4N
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BU of 6v4n by Molmil
Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-11-28
公開日2020-10-07
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020
6V4O
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BU of 6v4o by Molmil
Structure of human 2E01 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-11-28
公開日2020-10-07
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020
6C6Q
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BU of 6c6q by Molmil
Crystal Structure of the Murine Norovirus VP1 P Domain in complex with the CD300lf Receptor
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CMRF35-like molecule 1, ...
著者Nelson, C.A, Fremont, D.H.
登録日2018-01-19
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4HKJ
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BU of 4hkj by Molmil
Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb)
分子名称: Beta-2-microglobulin, CPXV203 protein, H-2 class I histocompatibility antigen, ...
著者McCoy IV, W.H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-10-15
公開日2012-11-14
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Mechanism of ER Retrieval of MHC Class I by Cowpox.
Plos Biol., 10, 2012
3HXO
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BU of 3hxo by Molmil
Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with DNA Aptamer ARC1172, an Inhibitor of VWF-Platelet Binding
分子名称: Aptamer ARC1172, von Willebrand factor
著者Huang, R.H, Sadler, J.E, Fremont, D.H, Diener, J.L, Schaub, R.G.
登録日2009-06-21
公開日2009-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A structural explanation for the antithrombotic activity of ARC1172, a DNA aptamer that binds von Willebrand factor domain A1.
Structure, 17, 2009
6C74
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BU of 6c74 by Molmil
Crystal Structure of Murine CD300lf in complex with phosphocholine
分子名称: CALCIUM ION, CMRF35-like molecule-1, PHOSPHOCHOLINE
著者Nelson, C.A, Fremont, D.H.
登録日2018-01-19
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.358 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E47
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BU of 6e47 by Molmil
Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Glycochenodeoxycholic Acid
分子名称: 1,2-ETHANEDIOL, CMRF35-like molecule 1, GLYCOCHENODEOXYCHOLIC ACID, ...
著者Nelson, C.A, Fremont, D.H.
登録日2018-07-16
公開日2018-09-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E48
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BU of 6e48 by Molmil
Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid
分子名称: (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Nelson, C.A, Fremont, D.H.
登録日2018-07-16
公開日2018-09-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4L5F
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BU of 4l5f by Molmil
Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
分子名称: Envelope protein, Heavy chain of E106 antibody (VH and CH1 of IgG2c), Light chain of E106 antibody (kappa)
著者Edeling, M.A, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-06-11
公開日2013-12-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
To be Published
4ZLT
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BU of 4zlt by Molmil
Crystal structure of viral chemokine binding protein R17 in complex with CCL3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 3, Putative uncharacterized protein
著者Lubman, O.Y, Fremont, D.H.
登録日2015-05-01
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.
Structure, 24, 2016
6P6P
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BU of 6p6p by Molmil
Crystal structure of hemagglutinin from influenza virus A/Sichuan/2/1987 (H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-06-04
公開日2020-07-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of hemagglutinin from influenza virus A/Sichuan/2/1987 (H3N2)
To Be Published
6W37
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BU of 6w37 by Molmil
STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN
分子名称: ORF7a protein
著者Nelson, C.A, Minasov, G, Shuvalova, L, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-03-09
公開日2020-04-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN
To be published
3I50
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BU of 3i50 by Molmil
Crystal structure of the West Nile Virus envelope glycoprotein in complex with the E53 antibody Fab
分子名称: Envelope glycoprotein, murine heavy chain (IgG3) of E53 monoclonal antibody Fab, murine kappa light chain of E53 monoclonal antibody Fab
著者Nybakken, G.E, Warren, J.T, Chen, B.R, Nelson, C.A, Fremont, D.H.
登録日2009-07-03
公開日2009-10-27
最終更新日2013-09-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody.
Embo J., 28, 2009
7K9H
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BU of 7k9h by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab 2B04 (one up, two down conformation)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B04 heavy chain, ...
著者Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-09-29
公開日2021-09-29
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
4ZKQ
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BU of 4zkq by Molmil
Viral chemokine binding protein R17 encoded by rodent gammaherpesvirus Peru ( RHVP)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Putative uncharacterized protein
著者Lubman, O.Y, Fremont, D.H.
登録日2015-04-30
公開日2015-11-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.
Structure, 24, 2016
3P54
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BU of 3p54 by Molmil
Crystal Structure of the Japanese Encephalitis Virus Envelope Protein, strain SA-14-14-2.
分子名称: envelope glycoprotein
著者Luca, V.C, Nelson, C.A, AbiMansour, J.P, Diamond, M.S, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-10-07
公開日2010-12-08
最終更新日2012-02-08
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Crystal structure of the Japanese encephalitis virus envelope protein.
J.Virol., 86, 2012
7K9J
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BU of 7k9j by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab 2H04 (three down conformation)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2H04 heavy chain, ...
著者Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-09-29
公開日2021-09-29
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021

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