8A8U
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![BU of 8a8u by Molmil](/molmil-images/mine/8a8u) | Mycobacterium tuberculosis ClpC1 hexamer structure | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | 著者 | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | 登録日 | 2022-06-24 | 公開日 | 2022-10-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
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8A8V
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![BU of 8a8v by Molmil](/molmil-images/mine/8a8v) | Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | 著者 | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | 登録日 | 2022-06-24 | 公開日 | 2022-10-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | 主引用文献 | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
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8A8W
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![BU of 8a8w by Molmil](/molmil-images/mine/8a8w) | Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | 著者 | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | 登録日 | 2022-06-24 | 公開日 | 2022-10-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.29 Å) | 主引用文献 | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
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6HWN
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![BU of 6hwn by Molmil](/molmil-images/mine/6hwn) | Structure of Thermus thermophilus ClpP in complex with a tripeptide. | 分子名称: | ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, Unknown tripeptide | 著者 | Felix, J, Schanda, P, Fraga, H, Morlot, C. | 登録日 | 2018-10-12 | 公開日 | 2019-09-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors. Sci Adv, 5, 2019
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6HWM
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![BU of 6hwm by Molmil](/molmil-images/mine/6hwm) | Structure of Thermus thermophilus ClpP in complex with bortezomib | 分子名称: | ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | 著者 | Felix, J, Schanda, P, Fraga, H, Morlot, C. | 登録日 | 2018-10-12 | 公開日 | 2019-09-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors. Sci Adv, 5, 2019
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