8A8U
 
 | | Mycobacterium tuberculosis ClpC1 hexamer structure | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | | 著者 | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | | 登録日 | 2022-06-24 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
|
|
8A8V
 | | Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | | 著者 | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | | 登録日 | 2022-06-24 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
|
|
8A8W
 | | Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | | 著者 | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | | 登録日 | 2022-06-24 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (4.29 Å) | | 主引用文献 | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
|
|
6HWN
 | | Structure of Thermus thermophilus ClpP in complex with a tripeptide. | | 分子名称: | ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, Unknown tripeptide | | 著者 | Felix, J, Schanda, P, Fraga, H, Morlot, C. | | 登録日 | 2018-10-12 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors.
Sci Adv, 5, 2019
|
|
6HWM
 | | Structure of Thermus thermophilus ClpP in complex with bortezomib | | 分子名称: | ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | | 著者 | Felix, J, Schanda, P, Fraga, H, Morlot, C. | | 登録日 | 2018-10-12 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors.
Sci Adv, 5, 2019
|
|
