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PDB: 3 results

5MRD
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BU of 5mrd by Molmil
Human PDK1-PKCiota Kinase Chimera in Complex with Allosteric Compound PS267 Bound to the PIF-Pocket
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Arencibia, J.M, Froehner, W, Krupa, M, Pastor-Flores, D, Merker, P, Oellerich, T, Neimanis, S, Schmithals, C, Koeberle, V, Suess, E, Zeuzem, S, Stark, H, Piiper, A, Odadzic, D, Schulze, J.O, Biondi, R.M.
Deposit date:2016-12-22
Release date:2017-01-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms.
ACS Chem. Biol., 12, 2017
8A6M
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Phosphatidylserine-dependent synaptic vesicle membrane sculpting by synaptogyrin
Descriptor: Isoform 1B of Synaptogyrin-1
Authors:Yu, T.K, Eastep, G.N, Flores, D, Zweckstetter, M.
Deposit date:2022-06-18
Release date:2023-05-24
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Phosphatidylserine-dependent structure of synaptogyrin remodels the synaptic vesicle membrane.
Nat.Struct.Mol.Biol., 30, 2023
4C0T
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Candida albicans PKh Kinase Domain
Descriptor: LIKELY PROTEIN KINASE
Authors:Schulze, J.O, Pastor-Flores, D, Biondi, R.M.
Deposit date:2013-08-07
Release date:2013-10-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:The Pif-Pocket as a Target for C. Albicans Pkh Selective Inhibitors.
Acs Chem.Biol., 8, 2013

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