1LOX
 
 | | RABBIT RETICULOCYTE 15-LIPOXYGENASE | | Descriptor: | (2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID, 15-LIPOXYGENASE, FE (II) ION | | Authors: | Gillmor, S.A, Villasenor, A, Fletterick, R.J, Sigal, E, Browner, M.F. | | Deposit date: | 1997-10-06 | | Release date: | 1998-11-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity.
Nat.Struct.Biol., 4, 1997
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1L5Q
 | | Human liver glycogen phosphorylase a complexed with caffeine, N-Acetyl-beta-D-glucopyranosylamine, and CP-403700 | | Descriptor: | CAFFEINE, Glycogen phosphorylase, liver form, ... | | Authors: | Ekstrom, J.L, Pauly, T.A, Carty, M.D, Soeller, W.C, Culp, J, Danley, D.E, Hoover, D.J, Treadway, J.L, Gibbs, E.M, Fletterick, R.J, Day, Y.S.N, Myszka, D.G, Rath, V.L. | | Deposit date: | 2002-03-07 | | Release date: | 2002-12-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure-activity analysis of the purine binding
site of human liver glycogen phosphorylase.
Chem.Biol., 9, 2002
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1EAP
 | | CRYSTAL STRUCTURE OF A CATALYTIC ANTIBODY WITH A SERINE PROTEASE ACTIVE SITE | | Descriptor: | IGG2B-KAPPA 17E8 FAB (HEAVY CHAIN), IGG2B-KAPPA 17E8 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE | | Authors: | Zhou, G.W, Guo, J, Huang, W, Scanlan, T.S, Fletterick, R.J. | | Deposit date: | 1994-08-10 | | Release date: | 1994-12-20 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of a catalytic antibody with a serine protease active site.
Science, 265, 1994
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1CU4
 | | CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE | | Descriptor: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, RECOGNITION PEPTIDE | | Authors: | Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E. | | Deposit date: | 1999-08-20 | | Release date: | 2000-04-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
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1CR9
 | | CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 | | Descriptor: | FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN | | Authors: | Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E. | | Deposit date: | 1999-08-14 | | Release date: | 2000-04-17 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
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1EZU
 | | ECOTIN Y69F, D70P BOUND TO D102N TRYPSIN | | Descriptor: | CALCIUM ION, ECOTIN, TRYPSIN II, ... | | Authors: | Gillmor, S.A, Takeuchi, T, Yang, S.Q, Craik, C.S, Fletterick, R.J. | | Deposit date: | 2000-05-11 | | Release date: | 2000-06-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases.
J.Mol.Biol., 299, 2000
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1EZS
 | | CRYSTAL STRUCTURE OF ECOTIN MUTANT M84R, W67A, G68A, Y69A, D70A BOUND TO RAT ANIONIC TRYPSIN II | | Descriptor: | CALCIUM ION, ECOTIN, TRYPSIN II, ... | | Authors: | Gillmor, S.A, Takeuchi, T, Yang, S.Q, Craik, C.S, Fletterick, R.J. | | Deposit date: | 2000-05-11 | | Release date: | 2000-06-23 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases.
J.Mol.Biol., 299, 2000
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1HGX
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1B89
 | | CLATHRIN HEAVY CHAIN PROXIMAL LEG SEGMENT (BOVINE) | | Descriptor: | PROTEIN (CLATHRIN HEAVY CHAIN) | | Authors: | Ybe, J.A, Brodsky, F.M, Hofmann, K, Lin, K, Liu, S.-H, Chen, L, Earnest, T.N, Fletterick, R.J, Hwang, P.K. | | Deposit date: | 1999-05-27 | | Release date: | 1999-06-04 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Clathrin self-assembly is mediated by a tandemly repeated superhelix.
Nature, 399, 1999
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1BG2
 | | HUMAN UBIQUITOUS KINESIN MOTOR DOMAIN | | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, KINESIN, ... | | Authors: | Kull, F.J, Sablin, E.P, Lau, R, Fletterick, R.J, Vale, R.D. | | Deposit date: | 1998-06-04 | | Release date: | 1998-10-14 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the kinesin motor domain reveals a structural similarity to myosin.
Nature, 380, 1996
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1BSX
 | | STRUCTURE AND SPECIFICITY OF NUCLEAR RECEPTOR-COACTIVATOR INTERACTIONS | | Descriptor: | 3,5,3'TRIIODOTHYRONINE, PROTEIN (GRIP1), PROTEIN (THYROID HORMONE RECEPTOR BETA) | | Authors: | Wagner, R.L, Darimont, B.D, Apriletti, J.W, Stallcup, M.R, Kushner, P.J, Baxter, J.D, Fletterick, R.J, Yamamoto, K.R. | | Deposit date: | 1998-08-31 | | Release date: | 1999-08-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structure and specificity of nuclear receptor-coactivator interactions.
Genes Dev., 12, 1998
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1FI8
 | | RAT GRANZYME B [N66Q] COMPLEXED TO ECOTIN [81-84 IEPD] | | Descriptor: | ECOTIN, NATURAL KILLER CELL PROTEASE 1 | | Authors: | Waugh, S.M, Harris, J.L, Fletterick, R.J, Craik, C.S. | | Deposit date: | 2000-08-03 | | Release date: | 2000-09-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity
Nat.Struct.Biol., 7, 2000
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