5DFA
 
 | | 3D structure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus | | Descriptor: | Beta-galactosidase, GLYCEROL, ZINC ION | | Authors: | Solomon, H.V, Tabachnikov, O, Lansky, S, Feinberg, H, Govada, L, Chayen, N.E, Shoham, Y, Shoham, G. | | Deposit date: | 2015-08-26 | | Release date: | 2015-12-09 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure-function relationships in Gan42B, an intracellular GH42 beta-galactosidase from Geobacillus stearothermophilus.
Acta Crystallogr.,Sect.D, 71, 2015
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3IFN
 | | X-ray structure of amyloid beta peptide:antibody (Abeta1-40:12A11) complex | | Descriptor: | 12A11 FAB antibody heavy chain, 12A11 FAB antibody light chain, Amyloid beta A4 protein | | Authors: | Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. | | Deposit date: | 2009-07-24 | | Release date: | 2009-11-17 | | Last modified: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
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2IT6
 | | Crystal Structure of DCSIGN-CRD with man2 | | Descriptor: | CALCIUM ION, CD209 antigen, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | | Authors: | Weis, W.I, Feinberg, H, Castelli, R, Drickamer, K, Seeberger, P.H. | | Deposit date: | 2006-10-19 | | Release date: | 2006-12-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins.
J.Biol.Chem., 282, 2007
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2IT5
 | | Crystal Structure of DCSIGN-CRD with man6 | | Descriptor: | CALCIUM ION, CD209 antigen, DCSIGN-CRD, ... | | Authors: | Weis, W.I, Feinberg, H, Castelli, R, Drickamer, K, Seeberger, P.H. | | Deposit date: | 2006-10-19 | | Release date: | 2006-12-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins.
J.Biol.Chem., 282, 2007
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4OIF
 | | 3D structure of Gan42B, a GH42 beta-galactosidase from G. | | Descriptor: | Beta-galactosidase, GLYCEROL, ZINC ION | | Authors: | Solomon, H.V, Tabachnikov, O, Feinberg, H, Shoham, Y, Shoham, G. | | Deposit date: | 2014-01-19 | | Release date: | 2015-02-04 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.448 Å) | | Cite: | Crystallization and preliminary crystallographic analysis of GanB, a GH42 intracellular beta-galactosidase from Geobacillus stearothermophilus.
Acta Crystallogr.,Sect.F, 69, 2013
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3IFL
 | | X-ray structure of amyloid beta peptide:antibody (Abeta1-7:12A11) complex | | Descriptor: | 12A11 FAB antibody heavy chain, 12A11 FAB antibody light chain, Amyloid beta A4 protein | | Authors: | Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. | | Deposit date: | 2009-07-24 | | Release date: | 2009-11-17 | | Last modified: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
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6HC7
 | | The crystal structure of BSAP, a zinc aminopeptidase from Bacillus subtilis (medium resolution) | | Descriptor: | ACETATE ION, Aminopeptidase Y (Arg Lys Leu preference), CHLORIDE ION, ... | | Authors: | Alhadeff, R, Lansky, S, Feinberg, H, Shoham, Y, Shoham, G. | | Deposit date: | 2018-08-14 | | Release date: | 2019-08-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structure of BSAP, a zinc aminopeptidase from Bacillus subtilis (medium resolution)
To Be Published
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4ZET
 | | Blood dendritic cell antigen 2 (BDCA-2) complexed with GalGlcNAcMan | | Descriptor: | C-type lectin domain family 4 member C, CALCIUM ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose | | Authors: | Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E. | | Deposit date: | 2015-04-20 | | Release date: | 2015-05-27 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2.
J.Biol.Chem., 290, 2015
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1Q3C
 | | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The E2A mutant at 2.3 resolution. | | Descriptor: | Endonuclease VIII, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Golan, G, Zharkov, D.O, Feinberg, H, Fernandes, A.S, Zaika, E.I, Kycia, J.H, Grollman, A.P, Shoham, G. | | Deposit date: | 2003-07-29 | | Release date: | 2004-08-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.
Nucleic Acids Res., 33, 2005
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6PWS
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6PWT
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6PWR
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3MMD
 | | Crystal structure of the W241A mutant of xylanase from Geobacillus stearothermophilus T-6 (XT6) complexed with hydrolyzed xylopentaose | | Descriptor: | CHLORIDE ION, Endo-1,4-beta-xylanase, SODIUM ION, ... | | Authors: | Solomon, V, Zolotnitsky, G, Feinberg, H, Tabachnikov, O, Shoham, Y, Shoham, G. | | Deposit date: | 2010-04-19 | | Release date: | 2011-04-27 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural-based rational mutagenesis of xylanases from G.stearothermophilus
TO BE PUBLISHED
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1ARM
 | | CARBOXYPEPTIDASE A WITH ZN REPLACED BY HG | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, HG-CARBOXYPEPTIDASE A=ALPHA= (COX), ... | | Authors: | Greenblatt, H.M, Feinberg, H, Tucker, P.A, Shoham, G. | | Deposit date: | 1994-11-22 | | Release date: | 1996-08-17 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Carboxypeptidase A: native, zinc-removed and mercury-replaced forms.
Acta Crystallogr.,Sect.D, 54, 1998
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1Q39
 | | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The WT enzyme at 2.8 resolution. | | Descriptor: | CALCIUM ION, Endonuclease VIII, ZINC ION | | Authors: | Golan, G, Zharkov, D.O, Feinberg, H, Fernandes, A.S, Zaika, E.I, Kycia, J.H, Grollman, A.P, Shoham, G. | | Deposit date: | 2003-07-29 | | Release date: | 2004-08-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.
Nucleic Acids Res., 33, 2005
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7JUD
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1Q3B
 | | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The R252A mutant at 2.05 resolution. | | Descriptor: | Endonuclease VIII, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Golan, G, Zharkov, D.O, Feinberg, H, Fernandes, A.S, Zaika, E.I, Kycia, J.H, Grollman, A.P, Shoham, G. | | Deposit date: | 2003-07-29 | | Release date: | 2004-08-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.
Nucleic Acids Res., 33, 2005
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7JUF
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1KWX
 | | Rat mannose protein A complexed with b-Me-Fuc. | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ... | | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-01-30 | | Release date: | 2002-07-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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1KWU
 | | Rat mannose binding protein A complexed with a-Me-Man | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ... | | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-01-30 | | Release date: | 2002-07-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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1KWW
 | | Rat mannose protein A complexed with a-Me-Fuc. | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ... | | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-01-30 | | Release date: | 2002-07-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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1KX1
 | | Rat mannose protein A complexed with Man6-GlcNAc2-Asn | | Descriptor: | CALCIUM ION, MANNOSE-BINDING PROTEIN A, alpha-D-mannopyranose, ... | | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-01-30 | | Release date: | 2002-07-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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1KWY
 | | Rat mannose protein A complexed with man-a13-man. | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ... | | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-01-30 | | Release date: | 2002-07-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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1KWT
 | | Rat mannose binding protein A (native, MPD) | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A | | Authors: | Ng, K.K.S, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-01-30 | | Release date: | 2002-07-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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1KZA
 | | Complex of MBP-C and Man-a13-Man | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN C, ... | | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-02-06 | | Release date: | 2002-07-05 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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