6UTA
 
 | | Crystal structure of Z004 iGL Fab in complex with ZIKV EDIII | | 分子名称: | Env, Z004 iGL Fab heavy chain, Z004 iGL Fab light chain | | 著者 | Esswein, S.R, Gristick, H.B, Keeffe, J.R, Bjorkman, P.J. | | 登録日 | 2019-10-29 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6UTE
 | | Crystal structure of Z032 Fab in complex with WNV EDIII | | 分子名称: | Envelope domain III, GLYCEROL, Z032 Fab heavy chain, ... | | 著者 | Esswein, S.R, Gristick, H.B, Keeffe, J.R, Bjorkman, P.J. | | 登録日 | 2019-10-29 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
5ACM
 | | Mcg immunoglobulin variable domain with methylene blue | | 分子名称: | 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, GLYCEROL, MCG, ... | | 著者 | Brumshtein, B, Esswein, S.R, Salwinski, L, Phillips, M.L, Ly, A.T, Cascio, D, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2015-08-17 | | 公開日 | 2015-12-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain.
Elife, 4, 2015
|
|
5ACL
 | | Mcg immunoglobulin variable domain with sulfasalazine | | 分子名称: | 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, MCG, SULFATE ION | | 著者 | Brumshtein, B, Esswein, S.R, Salwinski, L, Phillips, M.L, Ly, A.T, Cascio, D, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2015-08-17 | | 公開日 | 2015-12-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain.
Elife, 4, 2015
|
|
4UNU
 | | MCG - a dimer of lambda variable domains | | 分子名称: | IG LAMBDA CHAIN V-II REGION MGC, POLYETHYLENE GLYCOL (N=34), SULFATE ION | | 著者 | Brumshtein, B, Esswein, S.R, Landau, M, Ryan, C, Whitelegge, J, Casio, D, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2014-05-30 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
|
|
4UNT
 | | Induced monomer of the Mcg variable domain | | 分子名称: | IG LAMBDA CHAIN V-II REGION MGC, SULFATE ION | | 著者 | Brumshtein, B, Esswein, S.R, Landau, M, Ryan, C.M, Whitelegge, J.P, Phillips, M.L, Cascio, D, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2014-05-30 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
|
|
6DIX
 | | NFVFGT segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 98-103, assembled as an amyloid fibril | | 分子名称: | NFVFGT Immunoglobulin Light-Chain Variable Domain | | 著者 | Brumshtein, B, Esswein, S.R, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2018-05-23 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
J. Biol. Chem., 293, 2018
|
|
6DJ0
 | | ASLTVS segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 73-78, assembled as an amyloid fibril | | 分子名称: | ASLTVS segment from Light-Chain Variable Domain, Lambda Mcg | | 著者 | Brumshtein, B, Esswein, S.R, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2018-05-24 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
J. Biol. Chem., 293, 2018
|
|
6DIY
 | | YTFGQ segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 96-100, assembled as an amyloid fibril | | 分子名称: | YTFGQ segment Light-Chain Variable Domain Kappa AL09 | | 著者 | Brumshtein, B, Esswein, S.R, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2018-05-24 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | | 主引用文献 | Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
J. Biol. Chem., 293, 2018
|
|
7K90
 | | Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C144 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C144 Fab Heavy Chain, C144 Fab Light Chain, ... | | 著者 | Barnes, C.O, Esswein, S.R, Bjorkman, P.J. | | 登録日 | 2020-09-27 | | 公開日 | 2020-10-21 | | 最終更新日 | 2021-01-13 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
|
|
