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PDB: 261 件

3RRH
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BU of 3rrh by Molmil
Ternary Structure of the large fragment of Taq DNA polymerase bound to an abasic site and a ddTTP
分子名称: (5'-D(*AP*AP*AP*(3DR)P*AP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DT))-3'), ACETATE ION, ...
著者Marx, A, Diederichs, K, Obeid, S.
登録日2011-04-29
公開日2012-02-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Amino Acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase.
J.Biol.Chem., 287, 2012
3RR7
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BU of 3rr7 by Molmil
Binary Structure of the large fragment of Taq DNA polymerase bound to an abasic site
分子名称: (5'-D(*AP*AP*AP*(3DR)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA polymerase I, ...
著者Marx, A, Diederichs, K, Obeid, S.
登録日2011-04-29
公開日2012-02-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Amino Acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase.
J.Biol.Chem., 287, 2012
4KWX
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BU of 4kwx by Molmil
Linear structure of the Holliday junction sequence (TCGGCGCCGA)
分子名称: 5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3', MAGNESIUM ION
著者Skamrova, G, Laponogov, I, Campbell, N, Neidle, S.
登録日2013-05-24
公開日2014-11-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Linear structure of the Holliday junction sequence (TCGGCGCCGA)
To be Published
3QSC
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BU of 3qsc by Molmil
The first crystal structure of a human telomeric G-quadruplex DNA bound to a metal-containing ligand (a copper complex)
分子名称: 5'-D(*AP*GP*GP*GP*TP*(BRU)P*AP*GP*GP*GP*TP*T)-3', POTASSIUM ION, [2,2'-{(4,5-difluorobenzene-1,2-diyl)bis[(nitrilo-kappaN)methylylidene]}bis{5-[2-(piperidin-1-yl)ethoxy]phenolato-kappaO}(2-)]copper (II)
著者Campbell, N.H, Abd Karim, N.H, Parkinson, G.N, Vilar, R, Neidle, S.
登録日2011-02-21
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes.
J.Med.Chem., 55, 2012
3QSF
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BU of 3qsf by Molmil
The first crystal structure of a human telomeric G-quadruplex DNA bound to a metal-containing ligand (a nickel complex)
分子名称: 5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*T)-3', POTASSIUM ION, [2,2'-{(4,5-difluorobenzene-1,2-diyl)bis[(nitrilo-kappaN)methylylidene]}bis{5-[2-(piperidin-1-yl)ethoxy]phenolato-kappa O}(2-)]nickel (II)
著者Campbell, N.H, Abd Karim, N.H, Parkinson, G.N, Vilar, R, Neidle, S.
登録日2011-02-21
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes.
J.Med.Chem., 55, 2012
3QXR
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BU of 3qxr by Molmil
Crystal structure of the brominated CKIT-1 proto-oncogene promoter quadruplex DNA
分子名称: 5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*(BRU)P*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3', MAGNESIUM ION, POTASSIUM ION
著者Wei, D, Parkinson, G.N, Neidle, S.
登録日2011-03-02
公開日2012-01-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation.
Nucleic Acids Res., 40, 2012
3U0U
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BU of 3u0u by Molmil
Crystal structure of the DB1883-D(CGCGAATTCGCG)2 complex at 1.24 A resolution
分子名称: 2-(4'-carbamimidoylbiphenyl-4-yl)-1H-indole-6-carboximidamide, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION
著者Wei, D.G, Neidle, S.
登録日2011-09-29
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3U2N
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BU of 3u2n by Molmil
Crystal structure of DNA(CGCGAATTCGCG)2 at 1.25 angstroms
分子名称: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION
著者Wei, D.G, Neidle, S.
登録日2011-10-04
公開日2013-04-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3U08
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BU of 3u08 by Molmil
Crystal structure of DB1963-D(CGCGAATTCGCG)2 complex at 1.25 A resolution
分子名称: 4'-(5-carbamimidoyl-1H-benzimidazol-2-yl)biphenyl-4-carboxamide, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION
著者Wei, D.G, Neidle, S.
登録日2011-09-28
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3U05
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BU of 3u05 by Molmil
Crystal structure of DB1804-D(CGCGAATTCGCG)2 complex
分子名称: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 6-(1,4,5,6-tetrahydropyrimidin-2-yl)-2-[4'-(1,4,5,6-tetrahydropyrimidin-2-yl)biphenyl-4-yl]-1H-indole, MAGNESIUM ION
著者Wei, D.G, Neidle, S.
登録日2011-09-28
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
4H29
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BU of 4h29 by Molmil
B-raf dimer DNA quadruplex
分子名称: DNA (5'-D(*GP*GP*GP*CP*GP*GP*GP*GP*AP*GP*GP*GP*GP*GP*AP*AP*GP*GP*GP*A)-3'), POTASSIUM ION
著者Wei, D, Parkinson, G, Neidle, S.
登録日2012-09-12
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献Crystal Structure of a Promoter Sequence in the B-raf Gene Reveals an Intertwined Dimer Quadruplex.
J.Am.Chem.Soc., 135, 2013

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件を2024-08-14に公開中

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