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PDB: 66 件

3K16
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BU of 3k16 by Molmil
Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus
分子名称: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.
登録日2009-09-25
公開日2010-03-02
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K0H
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BU of 3k0h by Molmil
The crystal structure of BRCA1 BRCT in complex with a minimal recognition tetrapeptide with an amidated C-terminus
分子名称: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.
登録日2009-09-24
公開日2010-03-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K15
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BU of 3k15 by Molmil
Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with an amidated C-terminus
分子名称: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.
登録日2009-09-25
公開日2010-03-02
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K0K
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BU of 3k0k by Molmil
Crystal Structure of BRCA1 BRCT in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus.
分子名称: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.
登録日2009-09-24
公開日2010-03-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
4OFB
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BU of 4ofb by Molmil
Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
分子名称: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor
著者Sun, L, Edwards, R.A, Glover, J.N.M.
登録日2014-01-14
公開日2015-04-15
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Acs Chem.Biol., 10, 2015
4ORH
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BU of 4orh by Molmil
Crystal structure of RNF8 bound to the UBC13/MMS2 heterodimer
分子名称: E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.M.
登録日2014-02-11
公開日2014-02-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.802 Å)
主引用文献Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
7T3O
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BU of 7t3o by Molmil
Rat vesicular glutamate transporter 2 (VGLUT2) in low Cl condition
分子名称: Vesicular glutamate transporter 2
著者Li, F, Stroud, R.M, Edwards, R.H.
登録日2021-12-08
公開日2022-12-14
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Substrate Recognition, Directional Flux, and Allostery in a Synaptic Vesicle Glutamate Transporter
To Be Published
7T3N
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BU of 7t3n by Molmil
R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2)
分子名称: (1S,3R)-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID, (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Vesicular glutamate transporter 2
著者Li, F, Stroud, R.M, Edwards, R.H.
登録日2021-12-08
公開日2022-12-14
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Substrate Recognition, Directional Flux, and Allostery in a Synaptic Vesicle Glutamate Transporter
To Be Published
4ONM
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BU of 4onm by Molmil
Crystal structure of human Mms2/Ubc13 - NSC697923
分子名称: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-01-28
公開日2015-05-06
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ONN
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BU of 4onn by Molmil
Crystal structure of human Mms2/Ubc13 - BAY 11-7082
分子名称: 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-01-28
公開日2015-05-06
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ONL
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BU of 4onl by Molmil
Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P
分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-01-28
公開日2015-05-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4QPQ
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BU of 4qpq by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
分子名称: Relaxosome protein TraM, sbmA DNA1, sbmA DNA2
著者Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
登録日2014-06-24
公開日2014-09-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
4QPO
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BU of 4qpo by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
分子名称: PHOSPHATE ION, Relaxosome protein TraM
著者Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
登録日2014-06-24
公開日2014-09-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
5U6K
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BU of 5u6k by Molmil
Crystal structure of TopBP1 BRCT4/5 in complex with a BLM phosphopeptide
分子名称: Bloom Sydrome recQ helicase like protein (BLM), DNA topoisomerase 2-binding protein 1
著者Glover, J.N.M, Sun, L, Edwards, R.A.
登録日2016-12-08
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Insight into BLM Recognition by TopBP1.
Structure, 25, 2017
3QZC
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BU of 3qzc by Molmil
Structure of the periplasmic stress response protein CpxP
分子名称: Periplasmic protein CpxP, ZINC ION
著者Thede, G.L, Edwards, R.A, Glover, J.N.M.
登録日2011-03-04
公開日2011-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of the Periplasmic Stress Response Protein CpxP.
J.Bacteriol., 193, 2011
4NRG
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BU of 4nrg by Molmil
Crystal Structure of a human Mms2/Ubc13 D118G mutant
分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2013-11-26
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
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