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PDB: 359 件
2TPT
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STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE
分子名称: SULFATE ION, THYMIDINE PHOSPHORYLASE
著者Pugmire, M.J, Cook, W.J, Jasanoff, A, Walter, M.R, Ealick, S.E.
登録日1997-11-24
公開日1999-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
J.Mol.Biol., 281, 1998
2ISS
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BU of 2iss by Molmil
Structure of the PLP synthase Holoenzyme from Thermotoga maritima
分子名称: Glutamine amidotransferase subunit pdxT, PHOSPHATE ION, Pyridoxal biosynthesis lyase pdxS, ...
著者Zein, F, Zhang, Y, Kang, Y.N, Burns, K, Begley, T.P, Ealick, S.E.
登録日2006-10-18
公開日2007-01-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Insights into the Mechanism of the PLP Synthase Holoenzyme from Thermotoga maritima
Biochemistry, 45, 2006
5JE2
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Crystal structure of Burkholderia glumae ToxA Y7F mutant with bound S-adenosylhomocysteine (SAH)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, Methyl transferase, ...
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2016-04-17
公開日2016-05-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.519 Å)
主引用文献Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry, 55, 2016
2INT
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BU of 2int by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-4
分子名称: INTERLEUKIN-4
著者Walter, M.R, Cook, W.J, Zhao, B.G, Cameron Junior, R, Ealick, S.E, Walter Junior, R.L, Reichert, P, Nagabhushan, T.L, Trotta, P.P, Bugg, C.E.
登録日1993-07-22
公開日1994-01-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of recombinant human interleukin-4.
J.Biol.Chem., 267, 1992
1MSV
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BU of 1msv by Molmil
The S68A S-adenosylmethionine decarboxylase proenzyme processing mutant.
分子名称: 1,4-DIAMINOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-adenosylmethionine decarboxylase proenzyme
著者Tolbert, W.D, Zhang, Y, Bennett, E.M, Cottet, S.E, Ekstrom, J.L, Pegg, A.E, Ealick, S.E.
登録日2002-09-19
公開日2003-03-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanism of Human S-Adenosylmethionine Decarboxylase Proenzyme Processing as Revealed by the Structure of the S68A Mutant.
Biochemistry, 42, 2003
5HMB
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BU of 5hmb by Molmil
Crystal structure of S. sahachiroi AziG
分子名称: Azi13, SULFATE ION
著者Erb, M.S, Zhang, Y, Ealick, S.E.
登録日2016-01-15
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG.
Biochemistry, 55, 2016
4PNP
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BU of 4pnp by Molmil
THE HIGH RESOLUTION CRYSTAL STRUCTURE OF BOVINE SPLEEN PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX FORMS WITH PHOSPHATE AND 9-DEAZAINOSINE
分子名称: PHOSPHATE ION, PURINE NUCLEOSIDE PHOSPHORYLASE
著者Pugmire, M.J, Mao, C, Ealick, S.E.
登録日1998-03-30
公開日1999-03-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The High Resolution Crystal Structure of Bovine Spleen Purine Nucleoside Phosphorylase in Complex Forms with Phosphate and 9-Deazainosine
To be Published
1ESJ
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BU of 1esj by Molmil
CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S)
分子名称: HYDROXYETHYLTHIAZOLE KINASE, SULFATE ION
著者Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E.
登録日2000-04-10
公開日2000-08-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
4HHE
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Quinolinate synthase from Pyrococcus furiosus
分子名称: CHLORIDE ION, Quinolinate synthase A
著者Soriano, E.V, Zhang, Y, Settembre, E.C, Colabroy, K, Sanders, J.M, Dorrestein, P.C, Begley, T.P, Ealick, S.E.
登録日2012-10-09
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献Active-site models for complexes of quinolinate synthase with substrates and intermediates.
Acta Crystallogr.,Sect.D, 69, 2013
2THI
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BU of 2thi by Molmil
THIAMINASE I FROM BACILLUS THIAMINOLYTICUS
分子名称: SULFATE ION, THIAMINASE I
著者Campobasso, N, Begley, T.P, Ealick, S.E.
登録日1998-09-17
公開日1999-10-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of thiaminase-I from Bacillus thiaminolyticus at 2.0 A resolution.
Biochemistry, 37, 1998
5JE1
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BU of 5je1 by Molmil
Crystal structure of Burkholderia glumae ToxA with bound S-adenosylhomocysteine (SAH) and toxoflavin
分子名称: 1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione, Methyl transferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2016-04-17
公開日2016-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry, 55, 2016
5JDZ
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BU of 5jdz by Molmil
Crystal structure of Burkholderia glumae ToxA with bound S-adenosylhomocysteine (SAH)
分子名称: Methyl transferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2016-04-17
公開日2016-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry, 55, 2016
5JE5
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BU of 5je5 by Molmil
Crystal structure of Burkholderia glumae ToxA with bound S-adenosylhomocysteine (SAH) and 1-demethyltoxoflavin
分子名称: 6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione, Methyl transferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2016-04-17
公開日2016-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.564 Å)
主引用文献Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry, 55, 2016
5JE3
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BU of 5je3 by Molmil
Crystal structure of Burkholderia glumae ToxA Y7A mutant with bound S-adenosylhomocysteine (SAH)
分子名称: Methyl transferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2016-04-17
公開日2016-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.792 Å)
主引用文献Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry, 55, 2016
5JE0
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BU of 5je0 by Molmil
Crystal structure of Burkholderia glumae ToxA with bound S-adenosylhomocysteine (SAH) and 1,6-didemethyltoxoflavin
分子名称: Methyl transferase, S-ADENOSYL-L-HOMOCYSTEINE, pyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2016-04-17
公開日2016-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry, 55, 2016
5JDY
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BU of 5jdy by Molmil
Crystal structure of Burkholderia glumae ToxA Y7F mutant with bound S-adenosylhomocysteine (SAH) and toxoflavin
分子名称: 1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Methyl transferase, ...
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2016-04-17
公開日2016-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry, 55, 2016
5JE4
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BU of 5je4 by Molmil
Crystal structure of Burkholderia glumae ToxA Y7A mutant with bound S-adenosylhomocysteine (SAH)
分子名称: Methyl transferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2016-04-17
公開日2016-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.932 Å)
主引用文献Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry, 55, 2016
1ESQ
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BU of 1esq by Molmil
CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S) WITH ATP AND THIAZOLE PHOSPHATE.
分子名称: 4-METHYL-5-HYDROXYETHYLTHIAZOLE PHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, HYDROXYETHYLTHIAZOLE KINASE, ...
著者Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E.
登録日2000-04-10
公開日2000-08-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
3H0V
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Human AdoMetDC with 5'-Deoxy-5'-(dimethylsulfonio) adenosine
分子名称: 1,4-DIAMINOBUTANE, 5'-deoxy-5'-(dimethyl-lambda~4~-sulfanyl)adenosine, PYRUVIC ACID, ...
著者Bale, S, Brooks, W.H, Hanes, J.W, Mahesan, A.M, Guida, W.C, Ealick, S.E.
登録日2009-04-10
公開日2009-06-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase.
Biochemistry, 48, 2009
4JEN
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Structure of Clostridium botulinum CMP N-glycosidase, BcmB
分子名称: CMP N-GLYCOSIDASE, PHOSPHATE ION
著者Sikowitz, M.D, Cooper, L.E, Begley, T.P, Kaminski, P.A, Ealick, S.E.
登録日2013-02-27
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Reversal of the substrate specificity of CMP N-glycosidase to dCMP.
Biochemistry, 52, 2013
3IWC
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BU of 3iwc by Molmil
T. maritima AdoMetDC complex with S-Adenosylmethionine methyl ester
分子名称: S-ADENOSYLMETHIONINE METHYL ESTER, S-adenosylmethionine decarboxylase
著者Bale, S, Kavita, B, Ealick, S.E.
登録日2009-09-02
公開日2010-02-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Complexes of Thermotoga maritimaS-adenosylmethionine decarboxylase provide insights into substrate specificity.
Acta Crystallogr.,Sect.D, 66, 2010
2TPS
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BU of 2tps by Molmil
THIAMIN PHOSPHATE SYNTHASE
分子名称: MAGNESIUM ION, PROTEIN (THIAMIN PHOSPHATE SYNTHASE), PYROPHOSPHATE 2-, ...
著者Chiu, H.-J, Reddick, J.J, Begley, T.P, Ealick, S.E.
登録日1999-03-09
公開日1999-03-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structure of thiamin phosphate synthase from Bacillus subtilis at 1.25 A resolution.
Biochemistry, 38, 1999
3IWB
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BU of 3iwb by Molmil
T. maritima AdoMetDC in processed form
分子名称: S-adenosylmethionine decarboxylase
著者Bale, S, Kavita, B, Ealick, S.E.
登録日2009-09-02
公開日2010-02-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Complexes of Thermotoga maritimaS-adenosylmethionine decarboxylase provide insights into substrate specificity.
Acta Crystallogr.,Sect.D, 66, 2010
1JDV
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CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH ADENOSINE AND SULFATE ION
分子名称: 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, ADENOSINE, SULFATE ION
著者Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E.
登録日2001-06-15
公開日2001-10-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus.
J.Biol.Chem., 276, 2001
1JE1
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5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEX WITH GUANOSINE AND SULFATE
分子名称: 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, GUANOSINE, SULFATE ION
著者Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E.
登録日2001-06-15
公開日2001-10-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus.
J.Biol.Chem., 276, 2001

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