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PDB: 40 件

7RY6
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Solution NMR structural bundle of the first cyclization domain from yersiniabactin synthetase (Cy1) impacted by dynamics
分子名称: HMWP2 nonribosomal peptide synthetase
著者Kancherla, A.K, Mishra, S.H, Marincin, K.A, Nerli, S, Sgourakis, N.G, Dowling, D.P, Bouvignies, G, Frueh, D.P.
登録日2021-08-24
公開日2022-07-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Global protein dynamics as communication sensors in peptide synthetase domains.
Sci Adv, 8, 2022
6NHL
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Crystal structure of QueE from Escherichia coli
分子名称: 7-carboxy-7-deazaguanine synthase, DI(HYDROXYETHYL)ETHER, FE (III) ION, ...
著者Grell, T.A.J, Bell, B.N, Nguyen, C, Dowling, D.P, Drennan, C.L.
登録日2018-12-23
公開日2019-01-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
Protein Sci., 28, 2019
3RQD
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Ideal Thiolate-Zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8
分子名称: Histone deacetylase 8, Largazole, POTASSIUM ION, ...
著者Cole, K.E, Dowling, D.P, Christianson, D.W.
登録日2011-04-28
公開日2011-08-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.143 Å)
主引用文献Structural basis of the antiproliferative activity of largazole, a depsipeptide inhibitor of the histone deacetylases.
J.Am.Chem.Soc., 133, 2011
5TGS
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Crystal Structure of QueE from Bacillus subtilis with methionine bound
分子名称: 7-carboxy-7-deazaguanine synthase, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ...
著者Grell, T.A.J, Dowling, D.P, Drennan, C.L.
登録日2016-09-28
公開日2017-01-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.548 Å)
主引用文献7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
J. Am. Chem. Soc., 139, 2017
5TH5
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Crystal Structure of QueE from Bacillus subtilis with 6-carboxypterin-5'-deoxyadenosyl ester bound
分子名称: 5'-O-(2-amino-4-oxo-1,4-dihydropteridine-6-carbonyl)adenosine, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ...
著者Grell, T.A.J, Dowling, D.P, Drennan, C.L.
登録日2016-09-29
公開日2017-01-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.407 Å)
主引用文献7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
J. Am. Chem. Soc., 139, 2017
7M5W
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Crystal structure of the HMG-C1 domain of human capicua bound to DNA
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*TP*TP*TP*TP*TP*CP*AP*TP*TP*CP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*TP*AP*TP*GP*AP*AP*TP*GP*AP*AP*AP*AP*AP*GP*C)-3'), ...
著者Webb, J.P, Liew, J.J.M, Gnann, A.D, Dowling, D.P.
登録日2021-03-25
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular basis of DNA recognition by the HMG-box-C1 module of Capicua
Biorxiv, 2022
7JUA
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Crystal structure of the second heterocyclization domain of yersiniabactin synthetase at 2.35 A resolution
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, Irp2 protein, SODIUM ION
著者Xia, Y, Soule, J, Dowling, D.P.
登録日2020-08-19
公開日2021-09-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.
J.Biol.Chem., 2022
7JTJ
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Crystal structure of the second heterocyclization domain of yersiniabactin synthetase
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, Irp2 protein, SODIUM ION
著者Xia, Y, Gnann, A.D, Dowling, D.P.
登録日2020-08-17
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.
J.Biol.Chem., 298, 2022
6U76
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Structure of methanesulfinate monooxygenase MsuC from Pseudomonas fluorescens.
分子名称: methanesulfinate monooxygenase
著者Soule, J, Gnann, A.D, Parker, M.J, McKenna, K.C, Nguyen, S.V, Phan, N.T, Wicht, D.K, Dowling, D.P.
登録日2019-08-31
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献To be published
To Be Published
6UUG
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Structure of methanesulfinate monooxygenase MsuC from Pseudomonas fluorescens at 1.69 angstrom resolution
分子名称: Putative dehydrogenase
著者Soule, J, Gnann, A.D, Gonzalez, R, Parker, M.J, McKenna, K.C, Nguyen, S.V, Phan, N.T, Wicht, D.K, Dowling, D.P.
登録日2019-10-30
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.685 Å)
主引用文献Structure and function of the two-component flavin-dependent methanesulfinate monooxygenase within bacterial sulfur assimilation.
Biochem.Biophys.Res.Commun., 522, 2020
7JW9
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Ternary cocrystal structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens
分子名称: Alkanesulfonate monooxygenase, FLAVIN MONONUCLEOTIDE, SODIUM ION, ...
著者Liew, J.J.M, Dowling, D.P.
登録日2020-08-25
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
7K14
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Ternary soak structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens with FMN and methanesulfonate
分子名称: Alkanesulfonate monooxygenase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Liew, J.J.M, Dowling, D.P, El Saudi, I.M.
登録日2020-09-07
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
7K64
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Binary titrated soak structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens with FMN
分子名称: Alkanesulfonate monooxygenase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Liew, J.J.M, Dowling, D.P.
登録日2020-09-18
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
7JYB
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BU of 7jyb by Molmil
Binary soak structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens with FMN
分子名称: Alkanesulfonate monooxygenase, FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, ...
著者Liew, J.J.M, Dowling, D.P, El Saudi, I.M.
登録日2020-08-30
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
7JV3
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BU of 7jv3 by Molmil
Crystal structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens
分子名称: Alkanesulfonate monooxygenase
著者Liew, J.J.M, Dowling, D.P.
登録日2020-08-20
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
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