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PDB: 29 results
4MKY
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BU of 4mky by Molmil
Polymerase Domain from Mycobacterium tuberculosis Ligase D in complex with an annealed double-strand DNA break.
Descriptor: 5'-D(*DGP*DCP*DCP*DGP*DCP*DAP*DGP*DTP*DAP*DC)-3', 5'-D(P*DGP*DCP*DGP*DGP*DC)-3', DNA ligase-like protein Rv0938/MT0965
Authors:Brissett, N.C, Doherty, A.J.
Deposit date:2013-09-05
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase.
Cell Rep, 5, 2013
5OP0
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BU of 5op0 by Molmil
Structure of Prim-PolC from Mycobacterium smegmatis
Descriptor: DNA polymerase LigD, polymerase domain
Authors:Brissett, N.C, Doherty, A.J.
Deposit date:2017-08-09
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria.
Nat Commun, 8, 2017
7QAZ
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BU of 7qaz by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 - Primer Initiation Complex
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, COBALT (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-11-17
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
2R9L
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BU of 2r9l by Molmil
Polymerase Domain from Mycobacterium tuberculosis Ligase D in complex with DNA
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*DGP*DCP*DCP*DGP*DCP*DAP*DAP*DCP*DGP*DCP*DA)-3'), ...
Authors:Brissett, N.C, Fox, G.C, Pitcher, R.S, Doherty, A.J.
Deposit date:2007-09-13
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a NHEJ polymerase-mediated DNA synaptic complex
Science, 318, 2007
1CKN
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BU of 1ckn by Molmil
STRUCTURE OF GUANYLYLATED MRNA CAPPING ENZYME COMPLEXED WITH GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, MRNA CAPPING ENZYME, ...
Authors:Hakansson, K, Doherty, A.J, Wigley, D.B.
Deposit date:1997-04-20
Release date:1997-07-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes.
Cell(Cambridge,Mass.), 89, 1997
1CKM
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BU of 1ckm by Molmil
STRUCTURE OF TWO DIFFERENT CONFORMATIONS OF MRNA CAPPING ENZYME IN COMPLEX WITH GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MRNA CAPPING ENZYME
Authors:Hakansson, K, Doherty, A.J, Wigley, D.B.
Deposit date:1997-04-20
Release date:1997-07-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes.
Cell(Cambridge,Mass.), 89, 1997
7P9J
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BU of 7p9j by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 - Primer Initiation Complex
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, COBALT (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-07-27
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
8BAO
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BU of 8bao by Molmil
Dysgonamonadaceae bacterium CRISPR ancillary nuclease 2
Descriptor: BROMIDE ION, Cyclic tetra-adenylate (cA4), DUF1887 family protein, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2022-10-11
Release date:2022-11-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
8BGJ
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BU of 8bgj by Molmil
Crystal structure of Reverse Transcriptase domain from Caloramator australicus CART-CAPP
Descriptor: L(+)-TARTARIC ACID, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2022-10-27
Release date:2023-06-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
5N85
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BU of 5n85 by Molmil
Structure of RPA70N in complex with PrimPol (fragment 514-525)
Descriptor: DNA-directed primase/polymerase protein, Replication protein A 70 kDa DNA-binding subunit
Authors:Brissett, N.C, Doherty, A.J.
Deposit date:2017-02-23
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for PrimPol recruitment to replication forks by RPA.
Nat Commun, 8, 2017
5N8A
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BU of 5n8a by Molmil
Structure of RPA70N in complex with PrimPol (fragment 480-560)
Descriptor: DNA-directed primase/polymerase protein, Replication protein A 70 kDa DNA-binding subunit
Authors:Brissett, N.C, Doherty, A.J.
Deposit date:2017-02-23
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Molecular basis for PrimPol recruitment to replication forks by RPA.
Nat Commun, 8, 2017
1A0I
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BU of 1a0i by Molmil
ATP-DEPENDENT DNA LIGASE FROM BACTERIOPHAGE T7 COMPLEX WITH ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA LIGASE
Authors:Subramanya, H.S, Doherty, A.J, Ashford, S.R, Wigley, D.B.
Deposit date:1997-12-01
Release date:1998-03-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7.
Cell(Cambridge,Mass.), 85, 1996
6SA1
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BU of 6sa1 by Molmil
Post catalytic complex of Prim-PolC from Mycobacterium smegmatis with gapped DNA and 3'-dUTP
Descriptor: 1,2-ETHANEDIOL, 3'-DEOXY-URIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*CP*TP*CP*GP*CP*AP*AP*CP*GP*CP*A)-3'), ...
Authors:Brissett, N.C, Doherty, A.J.
Deposit date:2019-07-15
Release date:2020-11-18
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Molecular basis for DNA repair synthesis on short gaps by mycobacterial Primase-Polymerase C.
Nat Commun, 11, 2020
6SA0
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BU of 6sa0 by Molmil
Ternary complex of Prim-PolC from Mycobacterium smegmatis with 2nt gapped DNA and UpNHpp
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, CACODYLATE ION, ...
Authors:Brissett, N.C, Doherty, A.J.
Deposit date:2019-07-15
Release date:2020-11-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:Molecular basis for DNA repair synthesis on short gaps by mycobacterial Primase-Polymerase C.
Nat Commun, 11, 2020
5DMU
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BU of 5dmu by Molmil
Structure of the NHEJ polymerase from Methanocella paludicola
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, NHEJ Polymerase, ...
Authors:Brissett, N.C, Bartlett, E.J, Doherty, A.J.
Deposit date:2015-09-09
Release date:2015-10-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Molecular basis for DNA strand displacement by NHEJ repair polymerases.
Nucleic Acids Res., 44, 2016
5DMP
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BU of 5dmp by Molmil
Structure of the Archaeal NHEJ Phosphoesterase from Methanocella paludicola.
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Uncharacterized protein, ...
Authors:Brissett, N.C, Bartlett, E.J, Doherty, A.J.
Deposit date:2015-09-09
Release date:2015-10-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:Molecular basis for DNA strand displacement by NHEJ repair polymerases.
Nucleic Acids Res., 44, 2016
1GZH
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BU of 1gzh by Molmil
Crystal structure of the BRCT domains of human 53BP1 bound to the p53 tumor supressor
Descriptor: CELLULAR TUMOR ANTIGEN P53, SULFATE ION, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1, ...
Authors:Derbyshire, D.J, Doherty, A.J.
Deposit date:2002-05-22
Release date:2002-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Human 53BP1 Brct Domains Bound to P53 Tumour Suppressor
Embo J., 21, 2002
3PKY
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BU of 3pky by Molmil
Polymerase Domain from Mycobacterium tuberculosis Ligase D in complex with DNA, UTP and Manganese.
Descriptor: DNA 5'-D(*G*CP*CP*GP*CP*AP*AP*CP*GP*CP*AP*CP*G)-3', DNA 5'-D(P*GP*CP*GP*GP*C)-3', MANGANESE (II) ION, ...
Authors:Brissett, N.C, Fox, G.C, Pitcher, R.S, Doherty, A.J.
Deposit date:2010-11-12
Release date:2011-02-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a Preternary Complex Involving a Prokaryotic NHEJ DNA Polymerase.
Mol.Cell, 41, 2011
1UTU
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BU of 1utu by Molmil
Crystal structure of novel protein EMSY truncate
Descriptor: EMSY
Authors:Chavali, G.B, Basu, B.P, Doherty, A.J.
Deposit date:2003-12-10
Release date:2005-10-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of Emsy to Hp1Beta: Implications for Recruitment of Hp1Beta and Bs69.
Embo Rep., 6, 2005
1UZ3
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BU of 1uz3 by Molmil
Crystal structure of novel protein EMSY
Descriptor: EMSY PROTEIN
Authors:Chavali, G.B, Basu, B.P, Doherty, A.J.
Deposit date:2004-03-03
Release date:2005-10-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal Structure of the Ent Domain of Human Emsy.
J.Mol.Biol., 350, 2005
7NQD
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BU of 7nqd by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137
Descriptor: TPR_REGION domain-containing protein
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-03-01
Release date:2022-05-04
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
7NQE
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BU of 7nqe by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 with dGTP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-03-01
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
7NQF
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BU of 7nqf by Molmil
Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 with dsDNA
Descriptor: COBALT (II) ION, DNA(CGTGDG), TPR_REGION domain-containing protein
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2021-03-01
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Molecular basis for the initiation of DNA primer synthesis.
Nature, 605, 2022
2IRX
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BU of 2irx by Molmil
Crystal Structure of the Polymerase Domain from Mycobacterium tuberculosis Ligase D with GTP and Manganese.
Descriptor: DNA ligase-like protein Rv0938/MT0965, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION
Authors:Brissett, N.C, Pitcher, R.S, Doherty, A.J.
Deposit date:2006-10-16
Release date:2007-01-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and function of a mycobacterial NHEJ DNA repair polymerase.
J.Mol.Biol., 366, 2007
2IRU
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BU of 2iru by Molmil
Crystal Structure of the Polymerase Domain from Mycobacterium tuberculosis Ligase D
Descriptor: Putative DNA ligase-like protein Rv0938/MT0965
Authors:Brissett, N.C, Pitcher, R.S, Doherty, A.J.
Deposit date:2006-10-16
Release date:2007-01-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and function of a mycobacterial NHEJ DNA repair polymerase.
J.Mol.Biol., 366, 2007

 

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