3PG8
 
 | | Truncated form of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Thermotoga maritima | | Descriptor: | AZIDE ION, GLYCEROL, Phospho-2-dehydro-3-deoxyheptonate aldolase | | Authors: | Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J. | | Deposit date: | 2010-10-31 | | Release date: | 2011-01-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis
J.Biol.Chem., 286, 2011
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3PG9
 | | Thermotoga maritima DAH7P synthase in complex with inhibitor | | Descriptor: | AZIDE ION, CHLORIDE ION, NITRATE ION, ... | | Authors: | Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J. | | Deposit date: | 2010-10-31 | | Release date: | 2011-01-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis
J.Biol.Chem., 286, 2011
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6N2A
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6N2F
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3HIJ
 | | Crystal structure of dihydrodipicolinate synthase from Bacillus anthracis in complex with its substrate, pyruvate | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION | | Authors: | Voss, J.E, Scally, S.W, Dobson, R.C.J, Perugini, M.A. | | Deposit date: | 2009-05-20 | | Release date: | 2009-11-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax.
J.Biol.Chem., 285, 2010
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5DPT
 | | Crystal structure of PLEKHM1 LIR-fused human GABARAPL1_2-117 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Pleckstrin homology domain-containing family M member 1, Gamma-aminobutyric acid receptor-associated protein-like 1,Gamma-aminobutyric acid receptor-associated protein-like 1 | | Authors: | Ravichandran, A.C, Suzuki, H, Dobson, R.C.J. | | Deposit date: | 2015-09-14 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural and functional analysis of the GABARAP interaction motif (GIM).
EMBO Rep., 18, 2017
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5DPS
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5DPW
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4I7V
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4I7W
 | | Agrobacterium tumefaciens DHDPS with lysine and pyruvate | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, LYSINE | | Authors: | Atkinson, S.C, Dogovski, C, Dobson, R.C.J, Perugini, M.A. | | Deposit date: | 2012-12-01 | | Release date: | 2013-12-04 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structure, function and allostery of the bona fide DHDPS from the plant pathogen Agrobacterium tumefaciens
To be Published
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4IK0
 | | Crystal structure of diaminopimelate epimerase Y268A mutant from Escherichia coli | | Descriptor: | Diaminopimelate epimerase, IODIDE ION | | Authors: | Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A. | | Deposit date: | 2012-12-24 | | Release date: | 2013-02-20 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
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4I7U
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4IJZ
 | | Crystal structure of diaminopimelate epimerase from Escherichia coli | | Descriptor: | Diaminopimelate epimerase, NITRATE ION | | Authors: | Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A. | | Deposit date: | 2012-12-24 | | Release date: | 2013-02-20 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
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7LOY
 | | Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum | | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase | | Authors: | Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J. | | Deposit date: | 2021-02-11 | | Release date: | 2021-03-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum
To Be Published
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7JZB
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7JZC
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7JZD
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7JZG
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7JZF
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7JZ9
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7JZE
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7JZA
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7JZ7
 | | Dihydrodipicolinate synthase mutant S48F | | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, POTASSIUM ION | | Authors: | Board, A.J, Dobson, R.C.J. | | Deposit date: | 2020-09-01 | | Release date: | 2021-10-06 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Mapping the unchartered waters of dihydrodipicolinate synthase: a novel mechanism of allosteric inhibition.
To Be Published
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7JZ8
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7LVL
 | | Dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine from Candidatus Liberibacter solanacearum | | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase, LYSINE | | Authors: | Gilkes, J.M, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J.D. | | Deposit date: | 2021-02-25 | | Release date: | 2021-03-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine from Candidatus Liberibacter solanacearum
To Be Published
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