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PDB: 97 件

2A6N
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Dihydrodipicolinate synthase (E. coli)- mutant R138A
分子名称: Dihydrodipicolinate synthase, POTASSIUM ION
著者Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A.
登録日2005-07-03
公開日2005-10-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
2A6L
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Dihydrodipicolinate synthase (E. coli)- mutant R138H
分子名称: Dihydrodipicolinate synthase, POTASSIUM ION
著者Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A.
登録日2005-07-03
公開日2005-10-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
3C0J
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Structure of E. coli dihydrodipicolinate synthase complexed with hydroxypyruvate
分子名称: Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ...
著者Dobson, R.C.J.
登録日2008-01-21
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase
Protein Sci., 17, 2008
2PUR
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Structure of dihydrodipicolinate synthase mutant Thr44Ser at 1.7 A.
分子名称: Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ...
著者Dobson, R.C.J, Jameson, G.B, Gerrard, J.A.
登録日2007-05-09
公開日2008-05-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis.
Biochimie, 91, 2009
1YXC
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Structure of E. coli dihydrodipicolinate synthase to 1.9 A
分子名称: CHLORIDE ION, POTASSIUM ION, dihydrodipicolinate synthase
著者Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A.
登録日2005-02-20
公開日2005-08-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
1YXD
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Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A
分子名称: CHLORIDE ION, LYSINE, POTASSIUM ION, ...
著者Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A.
登録日2005-02-20
公開日2005-08-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
3QGU
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L,L-Diaminopimelate aminotransferase from Chlamydomonas reinhardtii
分子名称: AZIDE ION, GLYCEROL, LL-diaminopimelate aminotransferase, ...
著者Dobson, R.C.J, Giron, I, Hudson, A.O.
登録日2011-01-25
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献L,L-Diaminopimelate Aminotransferase from Chlamydomonas reinhardtii: A Target for Algaecide Development
Plos One, 6, 2011
3DU0
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E. coli dihydrodipicolinate synthase with first substrate, pyruvate, bound in active site
分子名称: CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ...
著者Dobson, R.C.J, Devenish, S.R.A, Gerrard, J.A, Jameson, G.B.
登録日2008-07-16
公開日2008-11-18
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate.
Acta Crystallogr.,Sect.F, 64, 2008
3DAQ
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Crystal structure of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus
分子名称: CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL
著者Dobson, R.C.J, Burgess, B.R, Jameson, G.B, Gerrard, J.A, Parker, M.W, Perugini, M.A.
登録日2008-05-29
公開日2008-08-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure and evolution of a novel dimeric enzyme from a clinically-important bacterial pathogen.
J.Biol.Chem., 2008
3I7Q
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Dihydrodipicolinate synthase mutant - K161A
分子名称: Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ...
著者Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P.
登録日2009-07-08
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
Biochimie, 92, 2010
3I7R
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Dihydrodipicolinate synthase - K161R
分子名称: CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ...
著者Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P.
登録日2009-07-08
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
Biochimie, 92, 2010
3I7S
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Dihydrodipicolinate synthase mutant - K161A - with the substrate pyruvate bound in the active site.
分子名称: Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ...
著者Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P.
登録日2009-07-08
公開日2010-04-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
Biochimie, 92, 2010
1S5T
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Crystal Structure Analysis of a mutant of DIHYDRODIPICOLINATE SYNTHASE--residue thr44 to val44
分子名称: Dihydrodipicolinate synthase
著者Dobson, R.C.J, Valegard, K, Gerrard, J.A.
登録日2004-01-21
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
J.MOL.BIOL., 338, 2004
1S5V
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Crystal Structure Analysis of a mutant of DIHYDRODIPICOLINATE SYNTHASE--residue Tyr107 to Phe107
分子名称: Dihydrodipicolinate synthase
著者Dobson, R.C.J, Valegard, K, Gerrard, J.A.
登録日2004-01-21
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
J.MOL.BIOL., 338, 2004
1S5W
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Crystal Structure Analysis of a mutant of DIHYDRODIPICOLINATE SYNTHASE--residue Tyr133 to Phe133
分子名称: Dihydrodipicolinate synthase
著者Dobson, R.C.J, Valegard, K, Gerrard, J.A.
登録日2004-01-21
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
J.MOL.BIOL., 338, 2004
3IRD
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Structure of dihydrodipicolinate synthase from Clostridium botulinum
分子名称: CHLORIDE ION, D-MALATE, Dihydrodipicolinate synthase, ...
著者Dobson, R.C.J, Atkinson, S, Perugini, M.A.
登録日2009-08-22
公開日2009-09-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structure of Cbot-DHDPS
To be Published
6O15
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Crystal structure of a putative oxidoreductase YjhC from Escherichia coli in complex with NAD(H)
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, Uncharacterized oxidoreductase YjhC
著者Horne, C.R, Kind, L, Davies, J.S, Dobson, R.C.
登録日2019-02-17
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism.
Proteins, 88, 2020
3TUU
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Structure of dihydrodipicolinate synthase from the common grapevine
分子名称: BROMIDE ION, CHLORIDE ION, dihydrodipicolinate synthase
著者Perugini, M.A, Dobson, R.C, Atkinson, S.C.
登録日2011-09-19
公開日2012-07-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine.
Plos One, 7, 2012
7T3E
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Structure of the sialic acid bound Tripartite ATP-independent Periplasmic (TRAP) periplasmic component SiaP from Photobacterium profundum
分子名称: N-acetyl-beta-neuraminic acid, SULFATE ION, TRAP-type C4-dicarboxylate transport system, ...
著者Davies, J.S, Currie, M.J, North, R.A, Dobson, R.C.J.
登録日2021-12-07
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
8B01
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Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in a nanodisc
分子名称: DECANE, DOCOSANE, HEXANE, ...
著者Davies, J.S, North, R.A, Dobson, R.C.J.
登録日2022-09-06
公開日2023-03-15
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
7QHA
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Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in amphipol
分子名称: Megabody c7HopQ, Putative TRAP-type C4-dicarboxylate transport system, large permease component, ...
著者North, R.A, Davies, J.S, Morado, D, Dobson, R.C.J.
登録日2021-12-11
公開日2022-12-21
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
8GEK
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Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum
分子名称: 4-hydroxy-tetrahydrodipicolinate synthase
著者Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J.
登録日2023-03-06
公開日2024-03-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum
To Be Published
8UUB
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Structure of hypothiocyanous acid reductase (Har) from Streptococcus pneumoniae
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Oxidoreductase, ...
著者Shearer, H.L, Currie, M.J, Dickerhof, N, Dobson, R.C.J.
登録日2023-10-31
公開日2024-04-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae.
J.Biol.Chem., 300, 2024
7RUM
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Endolysin from Escherichia coli O157:H7 phage FTEbC1, LysT84
分子名称: Endolysin, GLYCEROL
著者Love, M.J, Billington, C, Dobson, R.C.J.
登録日2021-08-17
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The structure and function of modular Escherichia coli O157:H7 bacteriophage FTBEc1 endolysin, LysT84: defining a new endolysin catalytic subfamily.
Biochem.J., 479, 2022
5KZE
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N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus
分子名称: GLYCEROL, N-acetylneuraminate lyase, SULFATE ION
著者North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J.
登録日2016-07-25
公開日2017-01-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.
FEBS Lett., 590, 2016

 

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