2OYY
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![BU of 2oyy by Molmil](/molmil-images/mine/2oyy) | HTHP: a hexameric tyrosine-coordinated heme protein | Descriptor: | Hexameric cytochrome, IODIDE ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Dobbek, H. | Deposit date: | 2007-02-23 | Release date: | 2007-04-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | HTHP: A Novel Class of Hexameric, Tyrosine-coordinated Heme Proteins J.Mol.Biol., 368, 2007
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6T7J
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![BU of 6t7j by Molmil](/molmil-images/mine/6t7j) | As-isolated Ni-free crystal structure of carbon monoxide dehydrogenase from Thermococcus sp. AM4 produced without CooC maturase | Descriptor: | (R,R)-2,3-BUTANEDIOL, Broken Fe4S4 cluster, CITRIC ACID, ... | Authors: | Dobbek, H, Jeoung, J.-H. | Deposit date: | 2019-10-22 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | The two CO-dehydrogenases of Thermococcus sp. AM4. Biochim Biophys Acta Bioenerg, 1861, 2020
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1N5W
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![BU of 1n5w by Molmil](/molmil-images/mine/1n5w) | Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Oxidized form | Descriptor: | CU(I)-S-MO(VI)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-07 | Release date: | 2002-12-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N63
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![BU of 1n63 by Molmil](/molmil-images/mine/1n63) | Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Carbon monoxide reduced state | Descriptor: | CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-08 | Release date: | 2002-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N61
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![BU of 1n61 by Molmil](/molmil-images/mine/1n61) | Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Dithionite reduced state | Descriptor: | CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-08 | Release date: | 2002-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N62
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![BU of 1n62 by Molmil](/molmil-images/mine/1n62) | Crystal Structure of the Mo,Cu-CO Dehydrogenase (CODH), n-butylisocyanide-bound state | Descriptor: | CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-08 | Release date: | 2002-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N60
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![BU of 1n60 by Molmil](/molmil-images/mine/1n60) | Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Cyanide-inactivated Form | Descriptor: | Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, Carbon monoxide dehydrogenase small chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-08 | Release date: | 2002-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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3N14
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![BU of 3n14 by Molmil](/molmil-images/mine/3n14) | XenA - W358A | Descriptor: | (R,R)-2,3-BUTANEDIOL, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... | Authors: | Dobbek, H, Spiegelhauer, O. | Deposit date: | 2010-05-15 | Release date: | 2010-09-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Determinants of substrate binding and protonation in the flavoenzyme xenobiotic reductase A J.Mol.Biol., 403, 2010
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2H90
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![BU of 2h90 by Molmil](/molmil-images/mine/2h90) | Xenobiotic reductase A in complex with coumarin | Descriptor: | (R,R)-2,3-BUTANEDIOL, COUMARIN, FLAVIN MONONUCLEOTIDE, ... | Authors: | Dobbek, H. | Deposit date: | 2006-06-08 | Release date: | 2006-08-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Xenobiotic reductase A in the degradation of quinoline by Pseudomonas putida 86: physiological function, structure and mechanism of 8-hydroxycoumarin reduction. J.Mol.Biol., 361, 2006
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2H8X
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![BU of 2h8x by Molmil](/molmil-images/mine/2h8x) | Xenobiotic Reductase A-oxidized | Descriptor: | FLAVIN MONONUCLEOTIDE, SULFATE ION, Xenobiotic reductase A | Authors: | Dobbek, H. | Deposit date: | 2006-06-08 | Release date: | 2006-08-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Xenobiotic reductase A in the degradation of quinoline by Pseudomonas putida 86: physiological function, structure and mechanism of 8-hydroxycoumarin reduction. J.Mol.Biol., 361, 2006
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2H8Z
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![BU of 2h8z by Molmil](/molmil-images/mine/2h8z) | Xenobiotic Reductase A in complex with 8-Hydroxycoumarin | Descriptor: | 8-HYDROXYCOUMARIN, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... | Authors: | Dobbek, H. | Deposit date: | 2006-06-08 | Release date: | 2006-08-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Xenobiotic reductase A in the degradation of quinoline by Pseudomonas putida 86: physiological function, structure and mechanism of 8-hydroxycoumarin reduction. J.Mol.Biol., 361, 2006
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2H9A
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![BU of 2h9a by Molmil](/molmil-images/mine/2h9a) | Corrinoid Iron-Sulfur Protein | Descriptor: | CO dehydrogenase/acetyl-CoA synthase, iron-sulfur protein, COBALAMIN, ... | Authors: | Dobbek, H. | Deposit date: | 2006-06-09 | Release date: | 2006-09-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into methyltransfer reactions of a corrinoid iron-sulfur protein involved in acetyl-CoA synthesis. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2IHR
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![BU of 2ihr by Molmil](/molmil-images/mine/2ihr) | RF2 of Thermus thermophilus | Descriptor: | Peptide chain release factor 2 | Authors: | Dobbek, H, Voertler, C.S, Sprinzl, M. | Deposit date: | 2006-09-27 | Release date: | 2007-02-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Release factors 2 from Escherichia coli and Thermus thermophilus: structural, spectroscopic and microcalorimetric studies. Nucleic Acids Res., 35, 2007
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1SU8
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![BU of 1su8 by Molmil](/molmil-images/mine/1su8) | Carbon Monoxide Induced Decomposition of the Active Site [Ni-4Fe-5S] Cluster of CO Dehydrogenase | Descriptor: | Carbon monoxide dehydrogenase 2, FE(4)-NI(1)-S(5) CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Dobbek, H, Svetlitchnyi, V, Liss, J, Meyer, O. | Deposit date: | 2004-03-26 | Release date: | 2004-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Carbon Monoxide Induced Decomposition of the Active Site [Ni-4Fe-5S] Cluster of CO Dehydrogenase J.Am.Chem.Soc., 126, 2004
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1SU7
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![BU of 1su7 by Molmil](/molmil-images/mine/1su7) | Carbon Monoxide Dehydrogenase from Carboxydothermus hydrogenoformans- DTT reduced state | Descriptor: | Carbon monoxide dehydrogenase 2, FE(4)-NI(1)-S(5) CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Dobbek, H, Svetlitchnyi, V, Liss, J, Meyer, O. | Deposit date: | 2004-03-26 | Release date: | 2004-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Carbon Monoxide Induced Decomposition of the Active Site [Ni-4Fe-5S] Cluster of CO Dehydrogenase J.Am.Chem.Soc., 126, 2004
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1SUF
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![BU of 1suf by Molmil](/molmil-images/mine/1suf) | Carbon Monoxide Dehydrogenase from Carboxydothermus hydrogenoformans-Inactive state | Descriptor: | Carbon Monoxide Dehydrogenase 2, FE(4)-NI(1)-S(5) CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Dobbek, H, Svetlitchnyi, V, Liss, J, Meyer, O. | Deposit date: | 2004-03-26 | Release date: | 2004-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Carbon Monoxide Induced Decomposition of the Active Site [Ni-4Fe-5S] Cluster of CO Dehydrogenase J.Am.Chem.Soc., 126, 2004
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1SU6
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![BU of 1su6 by Molmil](/molmil-images/mine/1su6) | Carbon monoxide dehydrogenase from Carboxydothermus hydrogenoformans: CO reduced state | Descriptor: | Carbon monoxide dehydrogenase 2, FE(4)-NI(1)-S(5) CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Dobbek, H, Svetlitchnyi, V, Liss, J, Meyer, O. | Deposit date: | 2004-03-26 | Release date: | 2004-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Carbon Monoxide Induced Decomposition of the Active Site [Ni-4Fe-5S] Cluster of CO Dehydrogenase J.Am.Chem.Soc., 126, 2004
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4UTK
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![BU of 4utk by Molmil](/molmil-images/mine/4utk) | XenA - reduced - Y183F variant | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, SULFATE ION, XENOBIOTIC REDUCTASE | Authors: | Werther, T, Dobbek, H. | Deposit date: | 2014-07-21 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Redox-dependent substrate-cofactor interactions in the Michaelis-complex of a flavin-dependent oxidoreductase Nat Commun, 8, 2017
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5AA5
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![BU of 5aa5 by Molmil](/molmil-images/mine/5aa5) | Actinobacterial-type NiFe-hydrogenase from Ralstonia eutropha H16 at 2.85 Angstrom resolution | Descriptor: | IRON/SULFUR CLUSTER, MALONIC ACID, NIFE-HYDROGENASE LARGE SUBUNIT, ... | Authors: | Schaefer, C, Bommer, M, Hennig, S, Jeoung, J.H, Dobbek, H, Lenz, O. | Deposit date: | 2015-07-23 | Release date: | 2016-01-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Structure of an Actinobacterial-Type [Nife]-Hydrogenase Reveals Insight Into O2-Tolerant H2 Oxidation. Structure, 24, 2016
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4PJ0
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![BU of 4pj0 by Molmil](/molmil-images/mine/4pj0) | Structure of T.elongatus Photosystem II, rows of dimers crystal packing | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Hellmich, J, Bommer, M, Burkhardt, A, Ibrahim, M, Kern, J, Meents, A, Mueh, F, Dobbek, H, Zouni, A. | Deposit date: | 2014-05-10 | Release date: | 2014-10-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.437 Å) | Cite: | Native-like Photosystem II Superstructure at 2.44 angstrom Resolution through Detergent Extraction from the Protein Crystal. Structure, 22, 2014
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7YYL
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![BU of 7yyl by Molmil](/molmil-images/mine/7yyl) | nucleotide-free DCCP:DCCP-R complex | Descriptor: | Dehydratase family protein, Double cubane cluster, IRON/SULFUR CLUSTER, ... | Authors: | Jeoung, J.-H, Dobbek, H. | Deposit date: | 2022-02-18 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structural basis for coupled ATP-driven electron transfer in the double-cubane cluster protein. Proc.Natl.Acad.Sci.USA, 119, 2022
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7YZQ
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![BU of 7yzq by Molmil](/molmil-images/mine/7yzq) | MgADP-AlF4-bound DCCP:DCCP-R complex | Descriptor: | (R,R)-2,3-BUTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, AMMONIUM ION, ... | Authors: | Jeoung, J.-H, Dobbek, H. | Deposit date: | 2022-02-21 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural basis for coupled ATP-driven electron transfer in the double-cubane cluster protein. Proc.Natl.Acad.Sci.USA, 119, 2022
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7YZM
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![BU of 7yzm by Molmil](/molmil-images/mine/7yzm) | MgADPNP-bound DCCP:DCCP-R complex | Descriptor: | (R,R)-2,3-BUTANEDIOL, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Jeoung, J.-H, Dobbek, H. | Deposit date: | 2022-02-21 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structural basis for coupled ATP-driven electron transfer in the double-cubane cluster protein. Proc.Natl.Acad.Sci.USA, 119, 2022
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8CJA
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![BU of 8cja by Molmil](/molmil-images/mine/8cja) | A225L/F231A variant of the CODH/ACS complex of C. hydrogenoformans | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CO-methylating acetyl-CoA synthase, ... | Authors: | Ruickoldt, J, Jeoung, J, Lennartz, F, Dobbek, H. | Deposit date: | 2023-02-13 | Release date: | 2024-02-21 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Coupling CO2 Reduction and Acetyl-CoA Formation: The Role of a CO Capturing Tunnel in Enzymatic Catalysis. Angew.Chem.Int.Ed.Engl., 2024
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8CJC
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![BU of 8cjc by Molmil](/molmil-images/mine/8cjc) | F515A variant of the CODH/ACS complex of C. hydrogenoformans | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CO-methylating acetyl-CoA synthase, ... | Authors: | Ruickoldt, J, Jeoung, J, Lennartz, F, Dobbek, H. | Deposit date: | 2023-02-13 | Release date: | 2024-02-21 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Coupling CO2 Reduction and Acetyl-CoA Formation: The Role of a CO Capturing Tunnel in Enzymatic Catalysis. Angew.Chem.Int.Ed.Engl., 2024
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