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PDB: 1 results

8V9M
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BU of 8v9m by Molmil
Human Ornithine Aminotransferase cocrystallized with its inhibitor, (R)-3-amino-5,5-difluorocyclohex-1-ene-1-carboxylic acid.
Descriptor: 3-fluoro-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]benzoic acid, GLYCEROL, Ornithine aminotransferase, ...
Authors:Vargas, A.L, Devitt, A, Kaley, N, Silverman, R, Liu, D.
Deposit date:2023-12-08
Release date:2024-05-08
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase.
Acs Chem.Biol., 19, 2024

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PDB entries from 2024-06-12

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