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PDB: 182 results

6HYA
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BU of 6hya by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193L
Descriptor: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel
Authors:Hu, H.D, Delarue, M.
Deposit date:2018-10-19
Release date:2018-12-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYZ
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BU of 6hyz by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT K248C
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2018-10-22
Release date:2018-12-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HY9
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BU of 6hy9 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193M
Descriptor: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel
Authors:Hu, H.D, Delarue, M.
Deposit date:2018-10-19
Release date:2018-12-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6I08
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BU of 6i08 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243C-I201W
Descriptor: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2018-10-25
Release date:2018-12-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6GO4
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BU of 6go4 by Molmil
TdT chimera (Loop1 of pol mu) - binary complex with ddCTP
Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA nucleotidylexotransferase,DNA-directed DNA/RNA polymerase mu,DNA nucleotidylexotransferase, MAGNESIUM ION, ...
Authors:Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M.
Deposit date:2018-06-01
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction.
J.Biol.Chem., 294, 2019
6GO3
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BU of 6go3 by Molmil
TdT chimera (Loop1 of pol mu) - apoenzyme
Descriptor: DNA nucleotidylexotransferase,DNA-directed DNA/RNA polymerase mu,DNA nucleotidylexotransferase
Authors:Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M.
Deposit date:2018-06-01
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction.
J.Biol.Chem., 294, 2019
6GO7
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BU of 6go7 by Molmil
TdT chimera (Loop1 of pol mu) - full DNA synapsis complex
Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*GP*C)-3'), ...
Authors:Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M.
Deposit date:2018-06-01
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction.
J.Biol.Chem., 294, 2019
6GO5
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BU of 6go5 by Molmil
TdT chimera (Loop1 of pol mu) - Ternary complex with 1-nt gapped DNA substrate
Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(*AP*CP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*GP*GP*CP*AP*AP*AP*CP*A)-3'), ...
Authors:Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M.
Deposit date:2018-06-01
Release date:2019-06-05
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction.
J.Biol.Chem., 294, 2019
6GO6
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BU of 6go6 by Molmil
TdT chimera (Loop1 of pol mu) - ternary complex with downstream dsDNA
Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*GP*GP*C)-3'), ...
Authors:Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M.
Deposit date:2018-06-01
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction.
J.Biol.Chem., 294, 2019
4HFI
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BU of 4hfi by Molmil
The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Sauguet, L, Corringer, P.J, Delarue, M.
Deposit date:2012-10-05
Release date:2013-02-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013
6F0N
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BU of 6f0n by Molmil
GLIC mutant E82A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F15
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BU of 6f15 by Molmil
GLIC mutant H127Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0M
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BU of 6f0m by Molmil
GLIC mutant E35Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F16
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BU of 6f16 by Molmil
GLIC mutant H277Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F10
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BU of 6f10 by Molmil
GLIC mutant D88N
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0R
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BU of 6f0r by Molmil
GLIC mutant E82Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F12
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BU of 6f12 by Molmil
GLIC mutant E181A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0U
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BU of 6f0u by Molmil
GLIC mutant E35A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0Z
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BU of 6f0z by Molmil
GLIC mutant D88N
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F11
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BU of 6f11 by Molmil
GLIC mutant D86A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0I
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BU of 6f0i by Molmil
GLIC mutant E26A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0V
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BU of 6f0v by Molmil
GLIC mutant E82Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0J
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BU of 6f0j by Molmil
GLIC mutant E26A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F13
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BU of 6f13 by Molmil
GLIC mutant E75A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6FL9
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BU of 6fl9 by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - Wild type 2.3 Angstrom resolution
Descriptor: Cys-loop ligand-gated ion channel, TETRAETHYLENE GLYCOL, nonyl beta-D-glucopyranoside
Authors:Hu, H, Delarue, M.
Deposit date:2018-01-25
Release date:2018-05-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

226707

數據於2024-10-30公開中

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