5VI5
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![BU of 5vi5 by Molmil](/molmil-images/mine/5vi5) | Structure of Mycobacterium smegmatis transcription initiation complex with a full transcription bubble | 分子名称: | 1,2-ETHANEDIOL, DNA (44-MER), DNA (49-MER), ... | 著者 | Darst, S.A, Campbell, E.A, Lilic, M. | 登録日 | 2017-04-14 | 公開日 | 2017-07-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.196 Å) | 主引用文献 | Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures. Nat Commun, 8, 2017
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6M7J
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![BU of 6m7j by Molmil](/molmil-images/mine/6m7j) | Mycobacterium tuberculosis RNAP with RbpA/us fork and Corallopyronin | 分子名称: | DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | 登録日 | 2018-08-20 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
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2Z2S
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![BU of 2z2s by Molmil](/molmil-images/mine/2z2s) | |
3BMB
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![BU of 3bmb by Molmil](/molmil-images/mine/3bmb) | |
8TOE
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![BU of 8toe by Molmil](/molmil-images/mine/8toe) | |
8TO6
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![BU of 8to6 by Molmil](/molmil-images/mine/8to6) | Escherichia coli RNA polymerase unwinding intermediate (I1d) at the lambda PR promoter | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Darst, S.A, Saecker, R.M, Mueller, A.U. | 登録日 | 2023-08-02 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
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8TOM
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8TO8
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![BU of 8to8 by Molmil](/molmil-images/mine/8to8) | Escherichia coli RNA polymerase unwinding intermediate (I1b) at the lambda PR promoter | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Darst, S.A, Saecker, R.M, Mueller, A.U. | 登録日 | 2023-08-03 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
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8TO1
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![BU of 8to1 by Molmil](/molmil-images/mine/8to1) | Escherichia coli RNA polymerase unwinding intermediate (I1a) at the lambda PR promoter | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Darst, S.A, Saecker, R.M, Mueller, A.U. | 登録日 | 2023-08-02 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
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1GRJ
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![BU of 1grj by Molmil](/molmil-images/mine/1grj) | |
4G8X
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![BU of 4g8x by Molmil](/molmil-images/mine/4g8x) | G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex | 分子名称: | ORF067, RNA polymerase sigma factor rpoD | 著者 | Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A. | 登録日 | 2012-07-23 | 公開日 | 2013-08-07 | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | 主引用文献 | Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein. Cell(Cambridge,Mass.), 151, 2012
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4G6D
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4G94
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![BU of 4g94 by Molmil](/molmil-images/mine/4g94) | G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex | 分子名称: | ORF067, RNA polymerase sigma factor rpoD | 著者 | Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A. | 登録日 | 2012-07-23 | 公開日 | 2013-01-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9971 Å) | 主引用文献 | Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein. Cell(Cambridge,Mass.), 151, 2012
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3LTI
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3LU0
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![BU of 3lu0 by Molmil](/molmil-images/mine/3lu0) | Molecular model of Escherichia coli core RNA polymerase | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Darst, S.A. | 登録日 | 2010-02-16 | 公開日 | 2010-09-29 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (11.2 Å) | 主引用文献 | Complete structural model of Escherichia coli RNA polymerase from a hybrid approach. Plos Biol., 8, 2010
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3MLQ
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6EEC
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![BU of 6eec by Molmil](/molmil-images/mine/6eec) | Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter captured by Corallopyronin | 分子名称: | DNA (63-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | 登録日 | 2018-08-13 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
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6EE8
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![BU of 6ee8 by Molmil](/molmil-images/mine/6ee8) | Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter | 分子名称: | DNA (60-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | 登録日 | 2018-08-13 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
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6EDT
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![BU of 6edt by Molmil](/molmil-images/mine/6edt) | Mycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoter | 分子名称: | DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | 登録日 | 2018-08-10 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
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5TJG
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5UI5
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![BU of 5ui5 by Molmil](/molmil-images/mine/5ui5) | |
5UI8
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![BU of 5ui8 by Molmil](/molmil-images/mine/5ui8) | structure of sigmaN-holoenzyme | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Darst, S.A, Campbell, E.A. | 登録日 | 2017-01-13 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.76 Å) | 主引用文献 | Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6C06
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![BU of 6c06 by Molmil](/molmil-images/mine/6c06) | Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. | 登録日 | 2017-12-27 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.15 Å) | 主引用文献 | Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
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6C04
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![BU of 6c04 by Molmil](/molmil-images/mine/6c04) | Mtb RNAP Holo/RbpA/double fork DNA -closed clamp | 分子名称: | DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. | 登録日 | 2017-12-27 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
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6C05
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![BU of 6c05 by Molmil](/molmil-images/mine/6c05) | Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. | 登録日 | 2017-12-27 | 公開日 | 2018-03-28 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (5.15 Å) | 主引用文献 | Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
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