6PYE
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![BU of 6pye by Molmil](/molmil-images/mine/6pye) | Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with NR160 | Descriptor: | 1,2-ETHANEDIOL, Hdac6 protein, N-[(1-benzyl-1H-tetrazol-5-yl)methyl]-N-{[4-(hydroxycarbamoyl)phenyl]methyl}-2-(trifluoromethyl)benzamide, ... | Authors: | Osko, J.D, Christianson, D.W. | Deposit date: | 2019-07-29 | Release date: | 2020-07-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.480003 Å) | Cite: | Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups. J.Med.Chem., 63, 2020
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6PZR
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![BU of 6pzr by Molmil](/molmil-images/mine/6pzr) | |
6Q0Z
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1QGF
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![BU of 1qgf by Molmil](/molmil-images/mine/1qgf) | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3R, 4S)N-PARA-TOLUENESULPHONYL-3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE | Descriptor: | (2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID, CALCIUM ION, ELASTASE, ... | Authors: | Wilmouth, R.C, Kassamally, S, Westwood, N.J, Sheppard, R.J, Claridge, T.D.W, Wright, P.A, Pritchard, G.J, Schofield, C.J. | Deposit date: | 1999-04-27 | Release date: | 1999-12-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanistic insights into the inhibition of serine proteases by monocyclic lactams. Biochemistry, 38, 1999
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6PZO
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6PZU
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5FPX
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![BU of 5fpx by Molmil](/molmil-images/mine/5fpx) | The structure of KdgF from Yersinia enterocolitica. | Descriptor: | NICKEL (II) ION, PECTIN DEGRADATION PROTEIN, PEPTIDE | Authors: | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | Deposit date: | 2015-12-03 | Release date: | 2016-05-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate. Proc.Natl.Acad.Sci.USA, 113, 2016
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5HJA
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![BU of 5hja by Molmil](/molmil-images/mine/5hja) | Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHDP | Descriptor: | (R)-2-amino-6-borono-2-(1-(3,4-dichlorobenzyl)piperidin-4-yl)hexanoic acid, Arginase, GLYCEROL, ... | Authors: | Hai, Y, Christianson, D.W. | Deposit date: | 2016-01-13 | Release date: | 2016-04-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors. Acta Crystallogr F Struct Biol Commun, 72, 2016
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5HJ9
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![BU of 5hj9 by Molmil](/molmil-images/mine/5hj9) | Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHPE | Descriptor: | 1,2-ETHANEDIOL, Arginase, GLYCEROL, ... | Authors: | Hai, Y, Christianson, D.W. | Deposit date: | 2016-01-13 | Release date: | 2016-04-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors. Acta Crystallogr F Struct Biol Commun, 72, 2016
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6PTD
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![BU of 6ptd by Molmil](/molmil-images/mine/6ptd) | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT H32L | Descriptor: | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | Authors: | Heinz, D.W. | Deposit date: | 1997-07-18 | Release date: | 1998-01-21 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis. Biochemistry, 36, 1997
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5H6H
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![BU of 5h6h by Molmil](/molmil-images/mine/5h6h) | Crystal Structure of Hyperthermophilic Thermotoga maritima L-Ribulose 3-Epimerase with Mn2+ | Descriptor: | MANGANESE (II) ION, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | Authors: | Cao, T.-P, Choi, J.M, Shin, S.M, Le, D.W, Lee, S.H. | Deposit date: | 2016-11-13 | Release date: | 2017-03-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.446 Å) | Cite: | TM0416, a Hyperthermophilic Promiscuous Nonphosphorylated Sugar Isomerase, Catalyzes Various C5and C6Epimerization Reactions Appl. Environ. Microbiol., 83, 2017
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5G2S
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![BU of 5g2s by Molmil](/molmil-images/mine/5g2s) | Crystal structure of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with molybdate | Descriptor: | GLYCEROL, MAGNESIUM ION, MOLYBDATE ION, ... | Authors: | Krausze, J, Probst, C, Kruse, T, Heinz, D.W, Mendel, R.R. | Deposit date: | 2016-04-13 | Release date: | 2017-02-15 | Method: | X-RAY DIFFRACTION (2.838 Å) | Cite: | Dimerization of the Plant Molybdenum Insertase Cnx1E is Required for Synthesis of the Molybdenum Cofactor. Biochem.J., 474, 2017
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5HDR
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![BU of 5hdr by Molmil](/molmil-images/mine/5hdr) | Crystal structure of a bacterial fucosidase with iminocyclitol (2S,3S,4R,5S)-3,4-dihydroxy-2-ethynyl-5-methylpyrrolidine | Descriptor: | Alpha-L-fucosidase, IMIDAZOLE, SULFATE ION, ... | Authors: | Wright, D.W, Davies, G.J. | Deposit date: | 2016-01-05 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a bacterial fucosidase with iminocyclitol (2S,3S,4R,5S)-3,4-dihydroxy-2-ethynyl-5-methylpyrrolidine To Be Published
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6PX9
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5FPZ
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![BU of 5fpz by Molmil](/molmil-images/mine/5fpz) | The structure of KdgF from Yersinia enterocolitica with malonate bound in the active site. | Descriptor: | MALONIC ACID, NICKEL (II) ION, PECTIN DEGRADATION PROTEIN | Authors: | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | Deposit date: | 2015-12-03 | Release date: | 2016-05-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate. Proc.Natl.Acad.Sci.USA, 113, 2016
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6RCV
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![BU of 6rcv by Molmil](/molmil-images/mine/6rcv) | PfRH5 bound to monoclonal antibodies R5.011 and R5.016 | Descriptor: | R5.011 heavy chain, R5.011 light chain, R5.016 heavy chain, ... | Authors: | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | Deposit date: | 2019-04-11 | Release date: | 2019-06-26 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (3.582 Å) | Cite: | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
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6RCU
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![BU of 6rcu by Molmil](/molmil-images/mine/6rcu) | PfRH5 bound to monoclonal antibodies R5.004 and R5.016 | Descriptor: | R5.004 heavy chain, R5.004 light chain, R5.016 heavy chain, ... | Authors: | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | Deposit date: | 2019-04-11 | Release date: | 2019-06-26 | Last modified: | 2019-08-21 | Method: | X-RAY DIFFRACTION (4.005 Å) | Cite: | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
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5GZ0
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![BU of 5gz0 by Molmil](/molmil-images/mine/5gz0) | Crystal structure of FM329, a recombinant Fab adopted from cetuximab | Descriptor: | FM329 heavy chain, FM329 light chain | Authors: | Sim, D.W, Kim, J.H, Kim, Y.P, Won, H.S. | Deposit date: | 2016-09-26 | Release date: | 2017-10-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of FM329, a recombinant Fab adopted from cetuximab To Be Published
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6RCQ
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![BU of 6rcq by Molmil](/molmil-images/mine/6rcq) | PfRH5-binding monoclonal antibody R5.011 | Descriptor: | ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ... | Authors: | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | Deposit date: | 2019-04-11 | Release date: | 2019-06-26 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
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6RCS
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![BU of 6rcs by Molmil](/molmil-images/mine/6rcs) | PfRH5-binding monoclonal antibody R5.016 | Descriptor: | ACETATE ION, R5.016 heavy chain, R5.016 light chain, ... | Authors: | Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K. | Deposit date: | 2019-04-11 | Release date: | 2019-06-26 | Last modified: | 2019-08-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
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3O2G
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![BU of 3o2g by Molmil](/molmil-images/mine/3o2g) | Crystal Structure of Human gamma-butyrobetaine,2-oxoglutarate dioxygenase 1 (BBOX1) | Descriptor: | 1,2-ETHANEDIOL, 3-CARBOXY-N,N,N-TRIMETHYLPROPAN-1-AMINIUM, Gamma-butyrobetaine dioxygenase, ... | Authors: | Krojer, T, Kochan, G, McDonough, M.A, von Delft, F, Leung, I.K.H, Henry, L, Claridge, T.D.W, Pilka, E, Ugochukwu, E, Muniz, J, Filippakopoulos, P, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K.L, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2010-07-22 | Release date: | 2010-09-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural and mechanistic studies on gamma-butyrobetaine hydroxylase. Chem. Biol., 17, 2010
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5FQ0
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![BU of 5fq0 by Molmil](/molmil-images/mine/5fq0) | The structure of KdgF from Halomonas sp. | Descriptor: | CITRATE ANION, KDGF, NICKEL (II) ION, ... | Authors: | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | Deposit date: | 2015-12-03 | Release date: | 2016-05-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate. Proc.Natl.Acad.Sci.USA, 113, 2016
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5I76
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![BU of 5i76 by Molmil](/molmil-images/mine/5i76) | Crystal structure of FM318, a recombinant Fab adopted from cetuximab | Descriptor: | FM318_heavy_cahin, FM318_light_chain | Authors: | Sim, D.W, Kim, J.H, Seok, S.H, Seo, M.D, Kim, Y.P, Won, H.S. | Deposit date: | 2016-02-16 | Release date: | 2016-12-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.922 Å) | Cite: | Bacterial production and structure-functional validation of a recombinant antigen-binding fragment (Fab) of an anti-cancer therapeutic antibody targeting epidermal growth factor receptor. Appl.Microbiol.Biotechnol., 100, 2016
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5G2R
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![BU of 5g2r by Molmil](/molmil-images/mine/5g2r) | Crystal structure of the Mo-insertase domain Cnx1E from Arabidopsis thaliana | Descriptor: | GLYCEROL, MAGNESIUM ION, MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1, ... | Authors: | Krausze, J, Saha, S, Probst, C, Kruse, T, Heinz, D.W, Mendel, R.R. | Deposit date: | 2016-04-13 | Release date: | 2017-02-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Dimerization of the Plant Molybdenum Insertase Cnx1E is Required for Synthesis of the Molybdenum Cofactor. Biochem.J., 474, 2017
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5IMP
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![BU of 5imp by Molmil](/molmil-images/mine/5imp) | Crystal structure of N299A Aspergillus terreus aristolochene synthase complexed with (1S,8S,9aR)-1,9a-dimethyl-8-(prop-1-en-2-yl)decahydroquinolizin-5-ium | Descriptor: | (1S,5S,8S,9aR)-1,9a-dimethyl-8-(prop-1-en-2-yl)octahydro-2H-quinolizinium, Aristolochene synthase, GLYCEROL, ... | Authors: | Chen, M, Christianson, D.W. | Deposit date: | 2016-03-06 | Release date: | 2016-05-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.038 Å) | Cite: | Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase. Biochemistry, 55, 2016
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