6PYE
 
 | | Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with NR160 | | 分子名称: | 1,2-ETHANEDIOL, Hdac6 protein, N-[(1-benzyl-1H-tetrazol-5-yl)methyl]-N-{[4-(hydroxycarbamoyl)phenyl]methyl}-2-(trifluoromethyl)benzamide, ... | | 著者 | Osko, J.D, Christianson, D.W. | | 登録日 | 2019-07-29 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.480003 Å) | | 主引用文献 | Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups.
J.Med.Chem., 63, 2020
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6PZR
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6Q0Z
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1QGF
 | | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3R, 4S)N-PARA-TOLUENESULPHONYL-3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE | | 分子名称: | (2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID, CALCIUM ION, ELASTASE, ... | | 著者 | Wilmouth, R.C, Kassamally, S, Westwood, N.J, Sheppard, R.J, Claridge, T.D.W, Wright, P.A, Pritchard, G.J, Schofield, C.J. | | 登録日 | 1999-04-27 | | 公開日 | 1999-12-29 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.
Biochemistry, 38, 1999
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6PZO
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6PZU
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5FPX
 | | The structure of KdgF from Yersinia enterocolitica. | | 分子名称: | NICKEL (II) ION, PECTIN DEGRADATION PROTEIN, PEPTIDE | | 著者 | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | | 登録日 | 2015-12-03 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5HJA
 | | Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHDP | | 分子名称: | (R)-2-amino-6-borono-2-(1-(3,4-dichlorobenzyl)piperidin-4-yl)hexanoic acid, Arginase, GLYCEROL, ... | | 著者 | Hai, Y, Christianson, D.W. | | 登録日 | 2016-01-13 | | 公開日 | 2016-04-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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5HJ9
 | | Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHPE | | 分子名称: | 1,2-ETHANEDIOL, Arginase, GLYCEROL, ... | | 著者 | Hai, Y, Christianson, D.W. | | 登録日 | 2016-01-13 | | 公開日 | 2016-04-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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6PTD
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT H32L | | 分子名称: | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W. | | 登録日 | 1997-07-18 | | 公開日 | 1998-01-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.
Biochemistry, 36, 1997
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5H6H
 | | Crystal Structure of Hyperthermophilic Thermotoga maritima L-Ribulose 3-Epimerase with Mn2+ | | 分子名称: | MANGANESE (II) ION, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | | 著者 | Cao, T.-P, Choi, J.M, Shin, S.M, Le, D.W, Lee, S.H. | | 登録日 | 2016-11-13 | | 公開日 | 2017-03-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.446 Å) | | 主引用文献 | TM0416, a Hyperthermophilic Promiscuous Nonphosphorylated Sugar Isomerase, Catalyzes Various C5and C6Epimerization Reactions
Appl. Environ. Microbiol., 83, 2017
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5G2S
 | | Crystal structure of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with molybdate | | 分子名称: | GLYCEROL, MAGNESIUM ION, MOLYBDATE ION, ... | | 著者 | Krausze, J, Probst, C, Kruse, T, Heinz, D.W, Mendel, R.R. | | 登録日 | 2016-04-13 | | 公開日 | 2017-02-15 | | 実験手法 | X-RAY DIFFRACTION (2.838 Å) | | 主引用文献 | Dimerization of the Plant Molybdenum Insertase Cnx1E is Required for Synthesis of the Molybdenum Cofactor.
Biochem.J., 474, 2017
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5HDR
 | | Crystal structure of a bacterial fucosidase with iminocyclitol (2S,3S,4R,5S)-3,4-dihydroxy-2-ethynyl-5-methylpyrrolidine | | 分子名称: | Alpha-L-fucosidase, IMIDAZOLE, SULFATE ION, ... | | 著者 | Wright, D.W, Davies, G.J. | | 登録日 | 2016-01-05 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of a bacterial fucosidase with iminocyclitol (2S,3S,4R,5S)-3,4-dihydroxy-2-ethynyl-5-methylpyrrolidine
To Be Published
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6PX9
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5FPZ
 | | The structure of KdgF from Yersinia enterocolitica with malonate bound in the active site. | | 分子名称: | MALONIC ACID, NICKEL (II) ION, PECTIN DEGRADATION PROTEIN | | 著者 | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | | 登録日 | 2015-12-03 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6RCV
 | | PfRH5 bound to monoclonal antibodies R5.011 and R5.016 | | 分子名称: | R5.011 heavy chain, R5.011 light chain, R5.016 heavy chain, ... | | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.582 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCU
 | | PfRH5 bound to monoclonal antibodies R5.004 and R5.016 | | 分子名称: | R5.004 heavy chain, R5.004 light chain, R5.016 heavy chain, ... | | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (4.005 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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5GZ0
 | | Crystal structure of FM329, a recombinant Fab adopted from cetuximab | | 分子名称: | FM329 heavy chain, FM329 light chain | | 著者 | Sim, D.W, Kim, J.H, Kim, Y.P, Won, H.S. | | 登録日 | 2016-09-26 | | 公開日 | 2017-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of FM329, a recombinant Fab adopted from cetuximab
To Be Published
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6RCQ
 | | PfRH5-binding monoclonal antibody R5.011 | | 分子名称: | ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ... | | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCS
 | | PfRH5-binding monoclonal antibody R5.016 | | 分子名称: | ACETATE ION, R5.016 heavy chain, R5.016 light chain, ... | | 著者 | Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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3O2G
 | | Crystal Structure of Human gamma-butyrobetaine,2-oxoglutarate dioxygenase 1 (BBOX1) | | 分子名称: | 1,2-ETHANEDIOL, 3-CARBOXY-N,N,N-TRIMETHYLPROPAN-1-AMINIUM, Gamma-butyrobetaine dioxygenase, ... | | 著者 | Krojer, T, Kochan, G, McDonough, M.A, von Delft, F, Leung, I.K.H, Henry, L, Claridge, T.D.W, Pilka, E, Ugochukwu, E, Muniz, J, Filippakopoulos, P, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K.L, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2010-07-22 | | 公開日 | 2010-09-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural and mechanistic studies on gamma-butyrobetaine hydroxylase.
Chem. Biol., 17, 2010
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5FQ0
 | | The structure of KdgF from Halomonas sp. | | 分子名称: | CITRATE ANION, KDGF, NICKEL (II) ION, ... | | 著者 | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | | 登録日 | 2015-12-03 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5I76
 | | Crystal structure of FM318, a recombinant Fab adopted from cetuximab | | 分子名称: | FM318_heavy_cahin, FM318_light_chain | | 著者 | Sim, D.W, Kim, J.H, Seok, S.H, Seo, M.D, Kim, Y.P, Won, H.S. | | 登録日 | 2016-02-16 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.922 Å) | | 主引用文献 | Bacterial production and structure-functional validation of a recombinant antigen-binding fragment (Fab) of an anti-cancer therapeutic antibody targeting epidermal growth factor receptor.
Appl.Microbiol.Biotechnol., 100, 2016
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5G2R
 | | Crystal structure of the Mo-insertase domain Cnx1E from Arabidopsis thaliana | | 分子名称: | GLYCEROL, MAGNESIUM ION, MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1, ... | | 著者 | Krausze, J, Saha, S, Probst, C, Kruse, T, Heinz, D.W, Mendel, R.R. | | 登録日 | 2016-04-13 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Dimerization of the Plant Molybdenum Insertase Cnx1E is Required for Synthesis of the Molybdenum Cofactor.
Biochem.J., 474, 2017
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5IMP
 | | Crystal structure of N299A Aspergillus terreus aristolochene synthase complexed with (1S,8S,9aR)-1,9a-dimethyl-8-(prop-1-en-2-yl)decahydroquinolizin-5-ium | | 分子名称: | (1S,5S,8S,9aR)-1,9a-dimethyl-8-(prop-1-en-2-yl)octahydro-2H-quinolizinium, Aristolochene synthase, GLYCEROL, ... | | 著者 | Chen, M, Christianson, D.W. | | 登録日 | 2016-03-06 | | 公開日 | 2016-05-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.038 Å) | | 主引用文献 | Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase.
Biochemistry, 55, 2016
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