1TZO
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![BU of 1tzo by Molmil](/molmil-images/mine/1tzo) | Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore | Descriptor: | CALCIUM ION, Protective antigen | Authors: | Lacy, D.B, Wigelsworth, D.J, Melnyk, R.A, Collier, R.J. | Deposit date: | 2004-07-10 | Release date: | 2004-08-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation Proc.Natl.Acad.Sci.USA, 101, 2004
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1TZN
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![BU of 1tzn by Molmil](/molmil-images/mine/1tzn) | Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore bound to the VWA domain of CMG2, an anthrax toxin receptor | Descriptor: | Anthrax toxin receptor 2, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Lacy, D.B, Wigelsworth, D.J, Melnyk, R.A, Collier, R.J. | Deposit date: | 2004-07-10 | Release date: | 2004-08-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation Proc.Natl.Acad.Sci.USA, 101, 2004
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1TSF
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![BU of 1tsf by Molmil](/molmil-images/mine/1tsf) | |
1XOK
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![BU of 1xok by Molmil](/molmil-images/mine/1xok) | crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide | Descriptor: | BROMIDE ION, Coat protein, alfalfa mosaic virus RNA 3' UTR | Authors: | Guogas, L.M, Filman, D.J, Hogle, J.M, Gehrke, L. | Deposit date: | 2004-10-06 | Release date: | 2005-01-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Cofolding organizes alfalfa mosaic virus RNA and coat protein for replication. Science, 306, 2004
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1XYD
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![BU of 1xyd by Molmil](/molmil-images/mine/1xyd) | NMR Solution Structure of Rat Zinc-Calcium-S100B, 20 Structures | Descriptor: | CALCIUM ION, S-100 protein, beta chain, ... | Authors: | Wilder, P.T, Varney, K.M, Weber, D.J. | Deposit date: | 2004-11-09 | Release date: | 2005-06-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of Zinc- and Calcium-Bound Rat S100B as Determined by Nuclear Magnetic Resonance Spectroscopy Biochemistry, 44, 2005
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1XOG
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![BU of 1xog by Molmil](/molmil-images/mine/1xog) | N9 Tern Influenza neuraminidase complexed with a 2,5-Disubstituted tetrahydrofuran-5-carboxylic acid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-2,5-ANHYDRO-3,4-DIDEOXY-4-(METHOXYCARBONYL)PENTONIC ACID, Neuraminidase, ... | Authors: | Wang, G.T, Wang, S, Gentles, R, Sowin, T, Maring, C.J, Kempf, D.J, Kati, W.M, Stoll, V, Stewart, K.D, Laver, G. | Deposit date: | 2004-10-06 | Release date: | 2005-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core. Bioorg.Med.Chem.Lett., 15, 2005
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1T4E
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![BU of 1t4e by Molmil](/molmil-images/mine/1t4e) | Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor | Descriptor: | (4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID, Ubiquitin-protein ligase E3 Mdm2 | Authors: | Grasberger, B.L, Schubert, C, Koblish, H.K, Carver, T.E, Franks, C.F, Zhao, S.Y, Lu, T, LaFrance, L.V, Parks, D.J. | Deposit date: | 2004-04-29 | Release date: | 2005-02-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells J.Med.Chem., 48, 2005
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1TJM
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![BU of 1tjm by Molmil](/molmil-images/mine/1tjm) | Crystallographic Identification of Sr2+ Coordination Site in Synaptotagmin I C2B Domain | Descriptor: | GLYCEROL, STRONTIUM ION, Synaptotagmin I | Authors: | Cheng, Y, Sequeira, S.M, Malinina, L, Tereshko, V, Sollner, T.H, Patel, D.J. | Deposit date: | 2004-06-06 | Release date: | 2004-09-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain Protein Sci., 13, 2004
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1TG5
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![BU of 1tg5 by Molmil](/molmil-images/mine/1tg5) | Crystal structures of plant 4-hydroxyphenylpyruvate dioxygenases complexed with DAS645 | Descriptor: | 4-hydroxyphenylpyruvate dioxygenase, FE (II) ION, [1-TERT-BUTYL-3-(2,4-DICHLOROPHENYL)-5-HYDROXY-1H-PYRAZOL-4-YL][2-CHLORO-4-(METHYLSULFONYL)PHENYL]METHANONE | Authors: | Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A. | Deposit date: | 2004-05-28 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases Biochemistry, 43, 2004
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1SUT
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![BU of 1sut by Molmil](/molmil-images/mine/1sut) | |
1TEN
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![BU of 1ten by Molmil](/molmil-images/mine/1ten) | |
1XO2
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![BU of 1xo2 by Molmil](/molmil-images/mine/1xo2) | Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin | Descriptor: | 3,7,3',4'-TETRAHYDROXYFLAVONE, Cell division protein kinase 6, Cyclin | Authors: | Lu, H.S, Chang, D.J, Baratte, B, Meijer, L, Schulze-Gahmen, U. | Deposit date: | 2004-10-05 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of a Human Cyclin-Dependent Kinase 6 Complex with a Flavonol Inhibitor, Fisetin. J.Med.Chem., 48, 2005
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1XU7
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![BU of 1xu7 by Molmil](/molmil-images/mine/1xu7) | Crystal Structure of the Interface Open Conformation of Tetrameric 11b-HSD1 | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Corticosteroid 11-beta-dehydrogenase, isozyme 1, ... | Authors: | Hosfield, D.J, Wu, Y, Skene, R.J, Hilger, M, Jennings, A, Snell, G.P, Aertgeerts, K. | Deposit date: | 2004-10-25 | Release date: | 2004-11-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Conformational Flexibility in Crystal Structures of Human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation. J.Biol.Chem., 280, 2005
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1XOE
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![BU of 1xoe by Molmil](/molmil-images/mine/1xoe) | N9 Tern influenza neuraminidase complexed with (2R,4R,5R)-5-(1-Acetylamino-3-methyl-butyl-pyrrolidine-2, 4-dicarobyxylic acid 4-methyl esterdase complexed with | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-4-(METHOXYCARBONYL)PROLINE, Neuraminidase, ... | Authors: | Wang, G.T, Wang, S, Gentles, R, Sowin, T, Maring, C.J, Kempf, D.J, Kati, W.M, Stoll, V, Stewart, K.D, Laver, G. | Deposit date: | 2004-10-06 | Release date: | 2005-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase
containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core. Bioorg.Med.Chem.Lett., 15, 2005
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1XYR
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![BU of 1xyr by Molmil](/molmil-images/mine/1xyr) | Poliovirus 135S cell entry intermediate | Descriptor: | Genome polyprotein, Coat protein VP1, Coat protein VP2, ... | Authors: | Bubeck, D, Filman, D.J, Cheng, N, Steven, A.C, Hogle, J.M, Belnap, D.M. | Deposit date: | 2004-11-10 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes. J.Virol., 79, 2005
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1B4C
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![BU of 1b4c by Molmil](/molmil-images/mine/1b4c) | SOLUTION STRUCTURE OF RAT APO-S100B USING DIPOLAR COUPLINGS | Descriptor: | PROTEIN (S-100 PROTEIN, BETA CHAIN) | Authors: | Weber, D.J, Drohat, A.C, Tjandra, N, Baldisseri, D.M. | Deposit date: | 1998-12-17 | Release date: | 1998-12-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The use of dipolar couplings for determining the solution structure of rat apo-S100B(betabeta). Protein Sci., 8, 1999
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1AR9
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![BU of 1ar9 by Molmil](/molmil-images/mine/1ar9) | P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT H2142Y | Descriptor: | MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE | Authors: | Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M. | Deposit date: | 1997-08-11 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural studies of poliovirus mutants that overcome receptor defects. Nat.Struct.Biol., 4, 1997
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1AL2
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![BU of 1al2 by Molmil](/molmil-images/mine/1al2) | P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT V1160I | Descriptor: | MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE | Authors: | Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M. | Deposit date: | 1997-06-09 | Release date: | 1997-11-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural studies of poliovirus mutants that overcome receptor defects. Nat.Struct.Biol., 4, 1997
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1DDV
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![BU of 1ddv by Molmil](/molmil-images/mine/1ddv) | CRYSTAL STRUCTURE OF THE HOMER EVH1 DOMAIN WITH BOUND MGLUR PEPTIDE | Descriptor: | GLGF-DOMAIN PROTEIN HOMER, METABOTROPIC GLUTAMATE RECEPTOR MGLUR5 | Authors: | Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J. | Deposit date: | 1999-11-11 | Release date: | 2000-05-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition. Neuron, 26, 2000
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1AR7
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![BU of 1ar7 by Molmil](/molmil-images/mine/1ar7) | P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT P1095S + H2142Y | Descriptor: | MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE | Authors: | Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M. | Deposit date: | 1997-08-11 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural studies of poliovirus mutants that overcome receptor defects. Nat.Struct.Biol., 4, 1997
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1ASJ
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![BU of 1asj by Molmil](/molmil-images/mine/1asj) | P1/MAHONEY POLIOVIRUS, AT CRYOGENIC TEMPERATURE | Descriptor: | MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE | Authors: | Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M. | Deposit date: | 1997-08-11 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural studies of poliovirus mutants that overcome receptor defects. Nat.Struct.Biol., 4, 1997
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1AR8
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![BU of 1ar8 by Molmil](/molmil-images/mine/1ar8) | P1/MAHONEY POLIOVIRUS, MUTANT P1095S | Descriptor: | MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE | Authors: | Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M. | Deposit date: | 1997-08-11 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural studies of poliovirus mutants that overcome receptor defects. Nat.Struct.Biol., 4, 1997
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1DDW
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![BU of 1ddw by Molmil](/molmil-images/mine/1ddw) | HOMER EVH1 DOMAIN UNLIGANDED | Descriptor: | GLGF-DOMAIN PROTEIN HOMER | Authors: | Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J. | Deposit date: | 1999-11-11 | Release date: | 2000-05-10 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition. Neuron, 26, 2000
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1AR6
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![BU of 1ar6 by Molmil](/molmil-images/mine/1ar6) | P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT V1160I +P1095S | Descriptor: | MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE | Authors: | Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M. | Deposit date: | 1997-08-11 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural studies of poliovirus mutants that overcome receptor defects. Nat.Struct.Biol., 4, 1997
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1EYO
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![BU of 1eyo by Molmil](/molmil-images/mine/1eyo) | |