7UJY
 
 | | Estrogen receptor alpha ligand binding domain Y537S mutant in complex with a methylated lasofoxifene derivative that enhances estrogen receptor alpha nuclear resonance time | | 分子名称: | (5R,6S)-5-(4-{2-[(2R)-2-methylpyrrolidin-1-yl]ethoxy}phenyl)-6-phenyl-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor | | 著者 | Hosfield, D.J, Greene, G.L, Fanning, S.W. | | 登録日 | 2022-03-31 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022
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7UNX
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7SVN
 | | DPP9 IN COMPLEX WITH LIGAND ICeD-1 | | 分子名称: | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile, Dipeptidyl peptidase 9 | | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | | 登録日 | 2021-11-19 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Acs Chem.Biol., 17, 2022
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1TZN
 | | Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore bound to the VWA domain of CMG2, an anthrax toxin receptor | | 分子名称: | Anthrax toxin receptor 2, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Lacy, D.B, Wigelsworth, D.J, Melnyk, R.A, Collier, R.J. | | 登録日 | 2004-07-10 | | 公開日 | 2004-08-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation
Proc.Natl.Acad.Sci.USA, 101, 2004
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1TZO
 | | Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore | | 分子名称: | CALCIUM ION, Protective antigen | | 著者 | Lacy, D.B, Wigelsworth, D.J, Melnyk, R.A, Collier, R.J. | | 登録日 | 2004-07-10 | | 公開日 | 2004-08-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation
Proc.Natl.Acad.Sci.USA, 101, 2004
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2PAC
 | | SOLUTION STRUCTURE OF FE(II) CYTOCHROME C551 FROM PSEUDOMONAS AERUGINOSA AS DETERMINED BY TWO-DIMENSIONAL 1H NMR | | 分子名称: | CYTOCHROME C551, HEME C | | 著者 | Detlefsen, D.J, Thanabal, V, Pecoraro, V.L, Wagner, G. | | 登録日 | 1993-05-05 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-10-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Fe(II) cytochrome c551 from Pseudomonas aeruginosa as determined by two-dimensional 1H NMR.
Biochemistry, 30, 1991
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1TSF
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2PIK
 | | CALICHEAMICIN GAMMA1I-DNA COMPLEX, NMR, 6 STRUCTURES | | 分子名称: | 2,4-dideoxy-4-(ethylamino)-3-O-methyl-alpha-L-threo-pentopyranose-(1-2)-4-amino-4,6-dideoxy-beta-D-glucopyranose, 2,6-dideoxy-4-thio-beta-D-allopyranose, 3-O-methyl-alpha-L-rhamnopyranose, ... | | 著者 | Kumar, R.A, Ikemoto, N, Patel, D.J. | | 登録日 | 1996-12-31 | | 公開日 | 1997-05-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the calicheamicin gamma 1I-DNA complex.
J.Mol.Biol., 265, 1997
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2PTW
 | | Crystal Structure of the T. brucei enolase complexed with sulphate, identification of a metal binding site IV | | 分子名称: | 1,2-ETHANEDIOL, Enolase, SULFATE ION, ... | | 著者 | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | | 登録日 | 2007-05-08 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
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1TTL
 | | Omega-conotoxin GVIA, a N-type calcium channel blocker | | 分子名称: | Omega-conotoxin GVIA | | 著者 | Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J. | | 登録日 | 2004-06-23 | | 公開日 | 2004-07-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels
J.Biol.Chem., 279, 2004
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1U2R
 | | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Jorgensen, R, Yates, S.P, Nilsson, J, Prentice, G.A, Teal, D.J, Merrill, A.R, Andersen, G.R. | | 登録日 | 2004-07-20 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
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2PZL
 | | Crystal structure of the Bordetella bronchiseptica enzyme WbmG in complex with NAD and UDP | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase, URIDINE-5'-DIPHOSPHATE | | 著者 | King, J.D, Harmer, N.J, Maskell, D.J, Blundell, T.L. | | 登録日 | 2007-05-18 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis.
J.Mol.Biol., 374, 2007
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1TT4
 | | Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium | | 分子名称: | MAGNESIUM ION, SULFATE ION, putative cytoplasmic protein | | 著者 | Miller, D.J, Shuvalova, L, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-06-21 | | 公開日 | 2004-08-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium
To be Published
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2PTY
 | | Crystal Structure of the T. brucei enolase complexed with PEP | | 分子名称: | 1,2-ETHANEDIOL, Enolase, PHOSPHOENOLPYRUVATE, ... | | 著者 | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | | 登録日 | 2007-05-08 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
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1TR6
 | | NMR solution structure of omega-conotoxin [K10]GVIA, a cyclic cysteine knot peptide | | 分子名称: | Omega-conotoxin GVIA | | 著者 | Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J. | | 登録日 | 2004-06-21 | | 公開日 | 2004-07-13 | | 最終更新日 | 2011-10-05 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels
J.Biol.Chem., 279, 2004
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2PHK
 | | THE CRYSTAL STRUCTURE OF A PHOSPHORYLASE KINASE PEPTIDE SUBSTRATE COMPLEX: KINASE SUBSTRATE RECOGNITION | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Lowe, E.D, Noble, M.E.M, Skamnaki, V.T, Oikonomakos, N.G, Owen, D.J, Johnson, L.N. | | 登録日 | 1998-06-18 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition.
EMBO J., 16, 1997
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2Q1W
 | | Crystal structure of the Bordetella bronchiseptica enzyme WbmH in complex with NAD+ | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase | | 著者 | King, J.D, Harmer, N.J, Maskell, D.J, Blundell, T.L. | | 登録日 | 2007-05-25 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis.
J.Mol.Biol., 374, 2007
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2PTX
 | | Crystal Structure of the T. brucei enolase complexed with sulphate in closed conformation | | 分子名称: | 1,2-ETHANEDIOL, Enolase, SULFATE ION, ... | | 著者 | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | | 登録日 | 2007-05-08 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
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2PTA
 | | PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES | | 分子名称: | PANDINUS TOXIN K-ALPHA | | 著者 | Tenenholz, T.C, Rogowski, R.S, Collins, J.H, Blaustein, M.P, Weber, D.J. | | 登録日 | 1996-11-26 | | 公開日 | 1997-12-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels.
Biochemistry, 36, 1997
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2PTZ
 | | Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-out conformation | | 分子名称: | 1,2-ETHANEDIOL, Enolase, PHOSPHONOACETOHYDROXAMIC ACID, ... | | 著者 | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | | 登録日 | 2007-05-08 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
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2PU0
 | | Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-in conformation | | 分子名称: | 1,2-ETHANEDIOL, Enolase, PHOSPHONOACETOHYDROXAMIC ACID, ... | | 著者 | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | | 登録日 | 2007-05-08 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
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2PU1
 | | Crystal Structure of the T. brucei enolase complexed with Fluoro-phosphonoacetohydroxamate (FPAH) | | 分子名称: | 1,2-ETHANEDIOL, Enolase, ZINC ION, ... | | 著者 | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | | 登録日 | 2007-05-08 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
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2PZK
 | | Crystal structure of the Bordetella bronchiseptica enzyme WbmG in complex with NAD | | 分子名称: | MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase | | 著者 | King, J.D, Harmer, N.J, Maskell, D.J, Blundell, T.L. | | 登録日 | 2007-05-18 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis.
J.Mol.Biol., 374, 2007
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1K8L
 | | XBY6: An analog of CK14 containing 6 dithiophosphate groups | | 分子名称: | FIRST STRAND OF CK14 DNA DUPLEX, SECOND STRAND OF CK14 DNA DUPLEX | | 著者 | Volk, D.E, Yang, X, Fennewald, S.M, King, D.J, Bassett, S.E, Venkitachalam, S, Herzog, N, Luxon, B.A, Gorenstein, D.G. | | 登録日 | 2001-10-24 | | 公開日 | 2003-04-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and design of dithiophosphate backbone aptamers targeting transcription factor NF-kappaB
Bioorg.Chem., 30, 2002
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1K8J
 | | NMR STRUCTURE OF THE CK14 DNA DUPLEX: A PORTION OF THE KNOWN NF-kB SEQUENCE CK1 | | 分子名称: | FIRST STRAND OF CK14 DNA DUPLEX, SECOND STRAND OF CK14 DNA DUPLEX | | 著者 | Volk, D.E, Yang, X, Fennewald, S.M, King, D.J, Bassett, S.E, Venkitachalam, S, Herzog, N, Luxon, B.A, Gorenstein, D.G. | | 登録日 | 2001-10-24 | | 公開日 | 2003-04-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and design of dithiophosphate backbone aptamers targeting transcription factor NF-kappaB
Bioorg.Chem., 30, 2002
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