5Y6O
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5XZE
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![BU of 5xze by Molmil](/molmil-images/mine/5xze) | Mouse cGAS bound to the inhibitor RU332 | 分子名称: | (3R)-3-[1-(3H-1lambda~4~,3-benzothiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-2-benzofuran-1(3H)-one, Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*G)-3'), ... | 著者 | Vincent, J, Adura, C, Gao, P, Luz, A, Lama, L, Asano, Y, Okamoto, R, Imaeda, T, Aida, J, Rothamel, K, Gogakos, T, Steinberg, J, Reasoner, S, Aso, K, Tuschl, T, Patel, D.J, Glickman, J.F, Ascano, M. | 登録日 | 2017-07-12 | 公開日 | 2017-10-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.177 Å) | 主引用文献 | Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun, 8, 2017
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4W6T
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![BU of 4w6t by Molmil](/molmil-images/mine/4w6t) | Crystal Structure of Full-Length Split GFP Mutant E115H/T118H With Copper Mediated Crystal Contacts, P 43 21 2 Space Group | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, COPPER (II) ION, ... | 著者 | Leibly, D.J, Waldo, G.S, Yeates, T.O. | 登録日 | 2014-08-20 | 公開日 | 2015-02-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.604 Å) | 主引用文献 | A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure, 23, 2015
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4W76
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![BU of 4w76 by Molmil](/molmil-images/mine/4w76) | Crystal Structure of Full-Length Split GFP Mutant D21H/K26C Disulfide and Metal-Mediated Dimer, P 21 21 21 Space Group, Form 2 | 分子名称: | COPPER (II) ION, fluorescent protein D21H/K26C | 著者 | Leibly, D.J, Waldo, G.S, Yeates, T.O. | 登録日 | 2014-08-21 | 公開日 | 2015-02-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure, 23, 2015
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4W7E
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![BU of 4w7e by Molmil](/molmil-images/mine/4w7e) | Crystal Structure of Full-Length Split GFP Mutant E124H/K126H With Copper Mediated Crystal Contacts, P 41 21 2 Space Group | 分子名称: | COPPER (II) ION, IMIDAZOLE, fluorescent protein D21H/K26H | 著者 | Leibly, D.J, Waldo, G.S, Yeates, T.O. | 登録日 | 2014-08-21 | 公開日 | 2015-02-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.592 Å) | 主引用文献 | A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure, 23, 2015
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4W7R
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![BU of 4w7r by Molmil](/molmil-images/mine/4w7r) | Crystal Structure of Full-Length Split GFP Mutant E124H/K126H Copper Mediated Dimer, P 21 Space Group | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, fluorescent protein E124H/K126C | 著者 | Leibly, D.J, Waldo, G.S, Yeates, T.O. | 登録日 | 2014-08-22 | 公開日 | 2015-03-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure, 23, 2015
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4W6N
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4W6B
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![BU of 4w6b by Molmil](/molmil-images/mine/4w6b) | Crystal Structure of a Superfolder GFP Mutant K26C Disulfide Dimer, P 21 21 21 Space Group | 分子名称: | CHLORIDE ION, MAGNESIUM ION, fluorescent protein K26C | 著者 | Pashkov, I, Sawaya, M.R, Leibly, D.J, Waldo, G.S, Yeates, T.O. | 登録日 | 2014-08-20 | 公開日 | 2015-02-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure, 23, 2015
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4W6G
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4W6J
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![BU of 4w6j by Molmil](/molmil-images/mine/4w6j) | Crystal Structure of Full-Length Split GFP Mutant D117C Disulfide Dimer, P 31 2 1 Space Group | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, fluorescent protein D117C | 著者 | Leibly, D.J, Waldo, G.S, Yeates, T.O. | 登録日 | 2014-08-20 | 公開日 | 2015-02-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure, 23, 2015
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4W72
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![BU of 4w72 by Molmil](/molmil-images/mine/4w72) | Crystal Structure of Full-Length Split GFP Mutant E115C/T118H Disulfide Dimer With Copper Mediated Crystal Contacts, P 21 21 21, Form 1 | 分子名称: | COPPER (II) ION, fluorescent protein E115C/T118H | 著者 | Leibly, D.J, Waldo, G.S, Yeates, T.O. | 登録日 | 2014-08-21 | 公開日 | 2015-02-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure, 23, 2015
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4W6O
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4W7C
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4W6R
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4W7X
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7TZJ
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![BU of 7tzj by Molmil](/molmil-images/mine/7tzj) | SARS CoV-2 PLpro in complex with inhibitor 3k | 分子名称: | DIMETHYL SULFOXIDE, N-[(3-fluorophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Papain-like protease, ... | 著者 | Calleja, D.J, Klemm, T, Lechtenberg, B.C, Kuchel, N.W, Lessene, G, Komander, D. | 登録日 | 2022-02-15 | 公開日 | 2022-03-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors. Front Chem, 10, 2022
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4WQ2
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![BU of 4wq2 by Molmil](/molmil-images/mine/4wq2) | Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound | 分子名称: | (2Z)-3-(6-bromo-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... | 著者 | Adams, S.E, Rizkallah, P.J, Miller, D.J, Hallett, M.B, Allemann, R.K. | 登録日 | 2014-10-21 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Conformationally restricted calpain inhibitors. Chem Sci, 6, 2015
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7U7H
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![BU of 7u7h by Molmil](/molmil-images/mine/7u7h) | Cysteate acyl-ACP transferase from Alistipes finegoldii | 分子名称: | 7-keto-8-aminopelargonate synthetase-like enzyme, PYRIDOXAL-5'-PHOSPHATE | 著者 | Radka, C.D, Miller, D.J, Frank, M.W, Rock, C.O. | 登録日 | 2022-03-07 | 公開日 | 2023-01-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii. J.Biol.Chem., 298, 2022
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4WNN
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![BU of 4wnn by Molmil](/molmil-images/mine/4wnn) | SPT16-H2A-H2B FACT HISTONE Complex | 分子名称: | Histone H2A.1, Histone H2B.1, PHOSPHATE ION, ... | 著者 | Kemble, D.J, Hill, C.P, Whitby, F.G, Formosa, T, McCullough, L.L. | 登録日 | 2014-10-13 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs. Mol.Cell, 60, 2015
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7UO0
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![BU of 7uo0 by Molmil](/molmil-images/mine/7uo0) | E.coli RNaseP Holoenzyme with Mg2+ | 分子名称: | CALCIUM ION, Precursor tRNA substrate G(-1) G(-2), RNase P RNA, ... | 著者 | Huang, W, Taylor, D.J. | 登録日 | 2022-04-12 | 公開日 | 2022-09-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. Nat Commun, 13, 2022
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7UO1
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![BU of 7uo1 by Molmil](/molmil-images/mine/7uo1) | E.coli RNaseP Holoenzyme with Mg2+ | 分子名称: | CALCIUM ION, E.coli RNase P RNA, Precursor tRNA substrate U(-1) and A(-2), ... | 著者 | Huang, W, Taylor, D.J. | 登録日 | 2022-04-12 | 公開日 | 2022-09-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. Nat Commun, 13, 2022
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7UO2
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![BU of 7uo2 by Molmil](/molmil-images/mine/7uo2) | E.coli RNaseP Holoenzyme with Mg2+ | 分子名称: | MAGNESIUM ION, RNase P RNA, Ribonuclease P protein component | 著者 | Huang, W, Taylor, D.J. | 登録日 | 2022-04-12 | 公開日 | 2022-09-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. Nat Commun, 13, 2022
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7UO5
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![BU of 7uo5 by Molmil](/molmil-images/mine/7uo5) | E.coli RNaseP Holoenzyme with Mg2+ | 分子名称: | CALCIUM ION, RNase P RNA, Ribonuclease P protein component | 著者 | Huang, W, Taylor, D.J. | 登録日 | 2022-04-12 | 公開日 | 2022-09-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. Nat Commun, 13, 2022
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4WQ3
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![BU of 4wq3 by Molmil](/molmil-images/mine/4wq3) | Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-bromoindol-3-yl)acrylic acid) bound | 分子名称: | (2Z)-3-(6-bromo-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid, CALCIUM ION, Calpain small subunit 1 | 著者 | Adams, S.E, Robinson, E.J, Rizkallah, P.J, Miller, D.J, Hallett, M.B, Allemann, R.K. | 登録日 | 2014-10-21 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Conformationally restricted calpain inhibitors. Chem Sci, 6, 2015
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7UDQ
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![BU of 7udq by Molmil](/molmil-images/mine/7udq) | Crystal structure of COQ8A-CA157 inhibitor complex in space group P1 | 分子名称: | 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial, ... | 著者 | Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. | 登録日 | 2022-03-20 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Small-molecule inhibition of the archetypal UbiB protein COQ8. Nat.Chem.Biol., 19, 2023
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