1JSH
 
 | | CRYSTAL STRUCTURE OF H9 HAEMAGGLUTININ COMPLEXED WITH LSTA RECEPTOR ANALOG | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Ha, Y, Stevens, D.J, Skehel, J.J, Wiley, D.C. | | Deposit date: | 2001-08-17 | | Release date: | 2001-09-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1JSM
 | | STRUCTURE OF H5 AVIAN HAEMAGGLUTININ | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ (HA1 CHAIN), ... | | Authors: | Ha, Y, Stevens, D.J, Skehel, J.J, Wiley, D.C. | | Deposit date: | 2001-08-17 | | Release date: | 2001-09-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes.
EMBO J., 21, 2002
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2KRA
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1JVC
 | | Dimeric DNA Quadruplex Containing Major Groove-Aligned A.T.A.T and G.C.G.C Tetrads Stabilized by Inter-Subunit Watson-Crick A:T and G:C Pairs | | Descriptor: | 5'-D(*GP*AP*GP*CP*AP*GP*GP*T)-3' | | Authors: | Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J. | | Deposit date: | 2001-08-29 | | Release date: | 2001-10-24 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs.
J.Mol.Biol., 312, 2001
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1JTW
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2KF8
 | | Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution | | Descriptor: | HUMAN TELOMERE DNA | | Authors: | Lim, K.W, Amrane, S, Bouaziz, S, Xu, W, Mu, Y, Patel, D.J, Luu, K.N, Phan, A.T. | | Deposit date: | 2009-02-12 | | Release date: | 2009-03-24 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
J.Am.Chem.Soc., 131, 2009
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2OE6
 | | 2.4A X-ray crystal structure of unliganded RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang | | Descriptor: | RNA (5'-R(*CP*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*C)-3') | | Authors: | Hermann, T, Tereshko, V, Skripkin, E, Patel, D.J. | | Deposit date: | 2006-12-28 | | Release date: | 2007-02-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Apramycin recognition by the human ribosomal decoding site.
Blood Cells Mol.Dis., 38, 2007
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1EXV
 | | HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH GLCNAC AND CP-403,700 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, LIVER GLYCOGEN PHOSPHORYLASE, N-acetyl-beta-D-glucopyranosylamine, ... | | Authors: | Rath, V.L, Ammirati, M, Danley, D.E, Ekstrom, J.L, Hynes, T.R, Olson, T.V, Hoover, D.J. | | Deposit date: | 2000-05-04 | | Release date: | 2000-11-01 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.
Chem.Biol., 7, 2000
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1EXY
 | | SOLUTION STRUCTURE OF HTLV-1 PEPTIDE BOUND TO ITS RNA APTAMER TARGET | | Descriptor: | HTLV-1 REX PEPTIDE, RNA APTAMER, 33-MER | | Authors: | Jiang, F, Gorin, A, Hu, W, Majumdar, A, Baskerville, S, Xu, W, Ellington, A, Patel, D.J. | | Deposit date: | 2000-05-05 | | Release date: | 2000-05-15 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples.
Structure Fold.Des., 7, 1999
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2OGB
 | | Crystal structure of the C-terminal domain of mouse Nrdp1 | | Descriptor: | GLYCEROL, RING finger protein 41, THIOCYANATE ION | | Authors: | Bouyain, S, Leahy, D.J. | | Deposit date: | 2007-01-05 | | Release date: | 2007-01-16 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3.
Protein Sci., 16, 2007
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2O0I
 | | crystal structure of the R185A mutant of the N-terminal domain of the Group B Streptococcus Alpha C protein | | Descriptor: | C protein alpha-antigen | | Authors: | Hogle, J.M, Filman, D.J, Baron, M.J, Madoff, L.C, Iglesias, A. | | Deposit date: | 2006-11-27 | | Release date: | 2007-02-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B streptococci into host cells.
J.Biol.Chem., 282, 2007
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2KHB
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2K7O
 | | Ca2+-S100B, refined with RDCs | | Descriptor: | CALCIUM ION, Protein S100-B | | Authors: | Wright, N.T, Inman, K.G, Levine, J.A, Weber, D.J. | | Deposit date: | 2008-08-17 | | Release date: | 2008-11-18 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Refinement of the solution structure and dynamic properties of Ca(2+)-bound rat S100B.
J.Biomol.Nmr, 42, 2008
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2KF3
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2KF5
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7BNO
 | | Open conformation of D614G SARS-CoV-2 spike with 2 Erect RBDs | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Benton, D.J, Wrobel, A.G, Rosenthal, P.B, Gamblin, S.J. | | Deposit date: | 2021-01-22 | | Release date: | 2021-02-03 | | Last modified: | 2021-03-10 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7BNM
 | | Closed conformation of D614G SARS-CoV-2 spike protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Benton, D.J, Wrobel, A.G, Rosenthal, P.B, Gamblin, S.J. | | Deposit date: | 2021-01-22 | | Release date: | 2021-02-03 | | Last modified: | 2021-03-10 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7BLR
 | | Vps35/Vps29 arch of fungal membrane-assembled retromer:Vps5 (SNX-BAR) complex. | | Descriptor: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | Authors: | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | | Deposit date: | 2021-01-18 | | Release date: | 2021-02-10 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
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7BLP
 | | Vps35/Vps29 arch of fungal membrane-assembled retromer:Grd19 complex | | Descriptor: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | Authors: | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | | Deposit date: | 2021-01-18 | | Release date: | 2021-02-10 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
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7BLN
 | | VPS35/VPS29 arch of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins | | Descriptor: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | Authors: | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | | Deposit date: | 2021-01-18 | | Release date: | 2021-02-10 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (8.9 Å) | | Cite: | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
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7DH7
 | | Crystal structure of apo XcZur | | Descriptor: | PHOSPHATE ION, Transcriptional regulator fur family, ZINC ION | | Authors: | Liu, F.M, Su, Z.H, Chen, P, Tian, X.L, Wu, L.J, Tang, D.J, Li, P.F, Deng, H.T, Tang, J.L, Ming, Z.H. | | Deposit date: | 2020-11-13 | | Release date: | 2021-06-09 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for zinc-induced activation of a zinc uptake transcriptional regulator.
Nucleic Acids Res., 49, 2021
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7DH8
 | | Crystal structure of holo XcZur | | Descriptor: | Transcriptional regulator fur family, ZINC ION | | Authors: | Liu, F.M, Su, Z.H, Chen, P, Tian, X.L, Wu, L.J, Tang, D.J, Li, P.F, Deng, H.T, Tang, J.L, Ming, Z.H. | | Deposit date: | 2020-11-13 | | Release date: | 2021-06-09 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural basis for zinc-induced activation of a zinc uptake transcriptional regulator.
Nucleic Acids Res., 49, 2021
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7BHS
 | | Crystal structure of MAT2a with quinazoline fragment 2 bound in the allosteric site | | Descriptor: | 6-chloranyl-2-methoxy-4-phenyl-quinazoline, S-ADENOSYLMETHIONINE, S-adenosylmethionine synthase isoform type-2 | | Authors: | Schimpl, M, De Fusco, C, Borjesson, U, Cheung, T, Collie, I, Evans, L, Narasimhan, P, Stubbs, C, Vazquez-Chantada, M, Wagner, D.J, Grondine, M, Tentarelli, S, Underwood, E, Argyrou, A, Bagal, S, Chiarparin, E, Robb, G, Scott, J.S. | | Deposit date: | 2021-01-11 | | Release date: | 2021-04-21 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Fragment-Based Design of a Potent MAT2a Inhibitor and in Vivo Evaluation in an MTAP Null Xenograft Model.
J.Med.Chem., 64, 2021
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7BHU
 | | Crystal structure of MAT2a with elaborated fragment 26 bound in the allosteric site | | Descriptor: | 1,2-ETHANEDIOL, 7-chloranyl-4-(dimethylamino)-1-(2-hydroxyethyl)quinazolin-2-one, S-ADENOSYLMETHIONINE, ... | | Authors: | Schimpl, M, De Fusco, C, Borjesson, U, Cheung, T, Collie, I, Evans, L, Narasimhan, P, Stubbs, C, Vazquez-Chantada, M, Wagner, D.J, Grondine, M, Tentarelli, S, Underwood, E, Argyrou, A, Bagal, S, Chiarparin, E, Robb, G, Scott, J.S. | | Deposit date: | 2021-01-11 | | Release date: | 2021-04-21 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Fragment-Based Design of a Potent MAT2a Inhibitor and in Vivo Evaluation in an MTAP Null Xenograft Model.
J.Med.Chem., 64, 2021
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7BHW
 | | Crystal structure of MAT2a bound to allosteric inhibitor (compound 29) | | Descriptor: | 7-chloranyl-4-(dimethylamino)-1-(3-methylphenyl)quinazolin-2-one, S-ADENOSYLMETHIONINE, S-adenosylmethionine synthase isoform type-2 | | Authors: | Schimpl, M, De Fusco, C, Borjesson, U, Cheung, T, Collie, I, Evans, L, Narasimhan, P, Stubbs, C, Vazquez-Chantada, M, Wagner, D.J, Grondine, M, Tentarelli, S, Underwood, E, Argyrou, A, Bagal, S, Chiarparin, E, Robb, G, Scott, J.S. | | Deposit date: | 2021-01-11 | | Release date: | 2021-04-21 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Fragment-Based Design of a Potent MAT2a Inhibitor and in Vivo Evaluation in an MTAP Null Xenograft Model.
J.Med.Chem., 64, 2021
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