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PDB: 1200 件

7N1I
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CryoEM structure of Venezuelan equine encephalitis virus VLP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid, E1 envelope glycoprotein, ...
著者Basore, K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-05-27
公開日2021-10-13
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor.
Nature, 598, 2021
7N1H
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CryoEM structure of Venezuelan equine encephalitis virus VLP in complex with the LDLRAD3 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid, ...
著者Basore, K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-05-27
公開日2021-10-13
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor.
Nature, 598, 2021
4OII
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West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab
分子名称: Heavy Chain of Fab fragment of 22NS1 Antibody, Light Chain of Fab fragment of 22NS1 Antibody, NON-STRUCTURAL PROTEIN NS1
著者Edeling, M.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-01-19
公開日2014-03-05
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of Flavivirus NS1 assembly and antibody recognition.
Proc.Natl.Acad.Sci.USA, 111, 2014
6C74
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Crystal Structure of Murine CD300lf in complex with phosphocholine
分子名称: CALCIUM ION, CMRF35-like molecule-1, PHOSPHOCHOLINE
著者Nelson, C.A, Fremont, D.H.
登録日2018-01-19
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.358 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4A8S
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Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
6CMJ
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Human CAMKK2 with GSK650393
分子名称: 1,2-ETHANEDIOL, 2-(2-methylpropyl)-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid, Calcium/calmodulin-dependent protein kinase kinase 2, ...
著者Williams, S.P, Reid, R.A, Price, D.J, Drewry, D.H.
登録日2018-03-05
公開日2018-04-04
最終更新日2018-05-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model.
Bioorg. Med. Chem. Lett., 28, 2018
7NCZ
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Crystal structure of Paradendryphiella salina PL7A alginate lyase mutant Y223F in complex with hexa-mannuronic acid
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alginate lyase (PL7), beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid
著者Fredslund, F, Welner, D.H, Wilkens, C.
登録日2021-01-29
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structure of Paradendryphiella salina PL7A alginate lyase mutant Y223F in complex with hexa-mannuronic acid
To Be Published
7NL3
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Crystal structure of Paradendryphiella salina PL7A alginate lyase mutant Y223F
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alginate lyase (PL7)
著者Fredslund, F, Welner, D.H, Wilkens, C.
登録日2021-02-22
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Paradendryphiella salina PL7A alginate lyase mutant Y223F
To Be Published
7NDE
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Trichoderma parareesei PL7A beta-glucuronan lyase
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glucuronan lyase
著者Fredslund, F, Welner, D.H, Wilkens, C.
登録日2021-02-01
公開日2022-03-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Glucuronan lyases from family PL7 use a Tyr/Tyr syn beta-elimination catalytic mechanism for glucuronan breakdown.
Chem.Commun.(Camb.), 60, 2024
7NM6
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Crystal structure of Paradendryphiella salina PL7A alginate lyase mutant Y223F in complex with di-mannuronic acid
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alginate lyase (PL7), beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid
著者Fredslund, F, Welner, D.H, Wilkens, C.
登録日2021-02-23
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structure of Paradendryphiella salina PL7A alginate lyase mutant Y223F in complex with di-mannuronic acid
To Be Published
4PDC
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BU of 4pdc by Molmil
Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D
分子名称: CPXV018 protein, NKG2-D type II integral membrane protein
著者Lazear, E, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-04-17
公開日2014-05-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献Structural basis of cowpox evasion of NKG2D immunosurveillance
Biorxiv, 2019
4NTC
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Crystal structure of GliT
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GliT
著者Scharf, D.H, Groll, M, Habel, A, Heinekamp, T, Hertweck, C, Brakhage, A.A, Huber, E.M.
登録日2013-12-02
公開日2014-03-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Flavoenzyme-Catalyzed Formation of Disulfide Bonds in Natural Products
Angew.Chem.Int.Ed.Engl., 53, 2014
4NTE
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Crystal structure of DepH
分子名称: CHLORIDE ION, DepH, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Scharf, D.H, Groll, M, Habel, A, Heinekamp, T, Hertweck, C, Brakhage, A.A, Huber, E.M.
登録日2013-12-02
公開日2014-03-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Flavoenzyme-Catalyzed Formation of Disulfide Bonds in Natural Products
Angew.Chem.Int.Ed.Engl., 53, 2014
4A8W
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BU of 4a8w by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4NNY
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Crystal structure of non-phosphorylated form of PKD2 phosphopeptide bound to HLA-A2
分子名称: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ...
著者Mohammed, F, Stones, D.H, Willcox, B.E.
登録日2013-11-19
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
5W7P
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BU of 5w7p by Molmil
Crystal structure of OxaC
分子名称: OxaC, S-ADENOSYLMETHIONINE
著者Newmister, S.A, Romminger, S, Schmidt, J.J, Williams, R.M, Smith, J.L, Berlinck, R.G.S, Sherman, D.H.
登録日2017-06-20
公開日2018-06-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway.
Org. Biomol. Chem., 16, 2018
4BWY
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BU of 4bwy by Molmil
P4 PROTEIN FROM BACTERIOPHAGE PHI8 (R32)
分子名称: P4
著者El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J.
登録日2013-07-05
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
5W1U
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Culex quinquefasciatus carboxylesterase B2
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Carboxylic ester hydrolase, MALONATE ION
著者Hopkins, D.H, Jackson, C.J.
登録日2017-06-04
公開日2017-08-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of an Insecticide Sequestering Carboxylesterase from the Disease Vector Culex quinquefasciatus: What Makes an Enzyme a Good Insecticide Sponge?
Biochemistry, 56, 2017
4NO5
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Crystal structure of non-phosphorylated form of AMPD2 phosphopeptide bound to HLA-A2
分子名称: 1,2-ETHANEDIOL, AMP deaminase 2, Beta-2-microglobulin, ...
著者Mohammed, F, Stones, D.H, Willcox, B.E.
登録日2013-11-19
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
4NO2
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Crystal structure of RQA_V phosphopeptide bound to HLA-A2
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Mohammed, F, Stones, D.H, Willcox, B.E.
登録日2013-11-19
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
5W7K
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BU of 5w7k by Molmil
Crystal structure of OxaG
分子名称: CHLORIDE ION, OxaG, S-ADENOSYL-L-HOMOCYSTEINE
著者Newmister, S.A, Romminger, S, Schmidt, J.J, Williams, R.M, Smith, J.L, Berlinck, R.G.S, Sherman, D.H.
登録日2017-06-20
公開日2018-06-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway.
Org. Biomol. Chem., 16, 2018
5W7S
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Crystal structure of OxaC in complex with sinefungin and meleagrin
分子名称: (3E,7aR,12aS)-6-hydroxy-3-[(1H-imidazol-4-yl)methylidene]-12-methoxy-7a-(2-methylbut-3-en-2-yl)-7a,12-dihydro-1H,5H-imidazo[1',2':1,2]pyrido[2,3-b]indole-2,5(3H)-dione, OxaC, SINEFUNGIN
著者Newmister, S.A, Romminger, S, Schmidt, J.J, Williams, R.M, Smith, J.L, Berlinck, R.G.S, Sherman, D.H.
登録日2017-06-20
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.948 Å)
主引用文献Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway.
Org. Biomol. Chem., 16, 2018
4NO0
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Crystal structure of non-phosphorylated form of RQA_V phosphopeptide bound to HLA-A2 in complex with LILRB1
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Mohammed, F, Stones, D.H, Willcox, B.E.
登録日2013-11-19
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
6D6H
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Triclinic lysozyme cryocooled to 100 K with 47% MPD as cryoprotectant
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Lysozyme C, NITRATE ION
著者Juers, D.H.
登録日2018-04-20
公開日2018-09-19
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.000064 Å)
主引用文献The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Acta Crystallogr D Struct Biol, 74, 2018
6D85
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Structure of the Bovine p85a BH domain E217K mutant
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018

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件を2024-10-02に公開中

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