6PVI
| Crystal structure of PhqK in complex with paraherquamide L | 分子名称: | (8aS,13S,13aR,14aS)-4,4,13,15,15-pentamethyl-12,13,14,14a,15,16-hexahydro-4H,8H,9H,11H-8a,13a-(epiminomethano)[1,4]dioxepino[2,3-a]indolizino[6,7-h]carbazol-17-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Fraley, A.E, Smith, J.L, Sherman, D.H. | 登録日 | 2019-07-20 | 公開日 | 2020-01-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | 主引用文献 | Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway. J.Am.Chem.Soc., 142, 2020
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6SU7
| Complex between a UDP-glucosyltransferase from Polygonum tinctorium capable of glucosylating indoxyl and 3,4-Dichloroaniline | 分子名称: | 3,4-Dichloroaniline, Glycosyltransferase | 著者 | Fredslund, F, Teze, D, Svensson, B, Adams, P.D, Welner, D.H. | 登録日 | 2019-09-13 | 公開日 | 2020-09-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | O-/N-/S-Specificity in Glycosyltransferase Catalysis: From Mechanistic Understanding to Engineering Acs Catalysis, 11, 2021
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6PVJ
| Crystal structure of PhqK in complex with malbrancheamide C | 分子名称: | (5aS,12aS,13aS)-9-bromo-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Fraley, A.E, Smith, J.L, Sherman, D.H. | 登録日 | 2019-07-20 | 公開日 | 2020-01-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway. J.Am.Chem.Soc., 142, 2020
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7ZF0
| Crystal structure of UGT85B1 from Sorghum bicolor in complex with UDP and p-hydroxymandelonitrile | 分子名称: | (2S)-HYDROXY(4-HYDROXYPHENYL)ETHANENITRILE, 1,2-ETHANEDIOL, Cyanohydrin beta-glucosyltransferase, ... | 著者 | Putkaradze, N, Fredslund, F, Welner, D.H. | 登録日 | 2022-03-31 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis. Plant J., 111, 2022
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6T2B
| Glycoside hydrolase family 109 from Akkermansia muciniphila in complex with GalNAc and NAD+. | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Glycosyl hydrolase family 109 protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Chaberski, E.K, Fredslund, F, Teze, D, Shuoker, B, Kunstmann, S, Karlsson, E.N, Hachem, M.A, Welner, D.H. | 登録日 | 2019-10-08 | 公開日 | 2020-02-26 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | The Catalytic Acid-Base in GH109 Resides in a Conserved GGHGG Loop and Allows for Comparable alpha-Retaining and beta-Inverting Activity in an N-Acetylgalactosaminidase from Akkermansia muciniphila Acs Catalysis, 2020
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3JS1
| Crystal structure of adipocyte fatty acid binding protein covalently modified with 4-hydroxy-2-nonenal | 分子名称: | Adipocyte fatty acid-binding protein, PHOSPHATE ION | 著者 | Hellberg, K, Grimsrud, P.A, Kruse, A.C, Banaszak, L.J, Ohlendorf, D.H, Bernlohr, D.A. | 登録日 | 2009-09-09 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | X-ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified with 4-hydroxy-2-nonenal. Protein Sci., 19, 2010
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3JSQ
| Crystal structure of adipocyte fatty acid binding protein non-covalently modified with 4-hydroxy-2-nonenal | 分子名称: | (2E,4R)-4-HYDROXYNON-2-ENAL, Adipocyte fatty acid-binding protein, CHLORIDE ION, ... | 著者 | Hellberg, K, Grimsrud, P.A, Kruse, A.C, Banaszak, L.J, Ohlendorf, D.H, Bernlohr, D.A. | 登録日 | 2009-09-10 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | X-ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified with 4-hydroxy-2-nonenal. Protein Sci., 19, 2010
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7ZNP
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7ZYC
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7ZYB
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3K55
| Structure of beta hairpin deletion mutant of beta toxin from Staphylococcus aureus | 分子名称: | Beta-hemolysin, CHLORIDE ION, SODIUM ION | 著者 | Kruse, A.C, Huseby, M, Shi, K, Digre, J, Ohlendorf, D.H, Earhart, C.A. | 登録日 | 2009-10-06 | 公開日 | 2011-01-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Structure of a mutant beta toxin from Staphylococcus aureus reveals domain swapping and conformational flexibility Acta Crystallogr.,Sect.F, 67, 2011
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6SU6
| Complex between a UDP-glucosyltransferase from Polygonum tinctorium capable of glucosylating indoxyl and UDP-glucose | 分子名称: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | 著者 | Fredslund, F, Teze, D, Svensson, B, Adams, P.D, Welner, D.H. | 登録日 | 2019-09-13 | 公開日 | 2020-09-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | O-/N-/S-Specificity in Glycosyltransferase Catalysis: From Mechanistic Understanding to Engineering Acs Catalysis, 11, 2021
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3M5R
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7ZER
| Crystal structure of UGT85B1 from Sorghum bicolor in complex with UDP | 分子名称: | 1,2-ETHANEDIOL, Cyanohydrin beta-glucosyltransferase, URIDINE-5'-DIPHOSPHATE | 著者 | Putkaradze, N, Fredslund, F, Welner, D.H. | 登録日 | 2022-03-31 | 公開日 | 2022-07-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis. Plant J., 111, 2022
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3MIA
| Crystal structure of HIV-1 Tat complexed with ATP-bound human P-TEFb | 分子名称: | Cell division protein kinase 9, Cyclin-T1, MAGNESIUM ION, ... | 著者 | Tahirov, T.H, Babayeva, N.D, Varzavand, K, Cooper, J.J, Sedore, S.C, Price, D.H. | 登録日 | 2010-04-09 | 公開日 | 2010-06-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of HIV-1 Tat complexed with human P-TEFb. Nature, 465, 2010
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8OHZ
| Yeast 20S proteasome in complex with a photoswitchable cepafungin derivative (transCep1) | 分子名称: | (2~{S},3~{R})-2-[2-[4-[2-(4-ethylphenyl)hydrazinyl]phenyl]ethanoylamino]-~{N}-[(5~{S},8~{S},10~{S})-5-methyl-10-oxidanyl-2,7-bis(oxidanylidene)-1,6-diazacyclododec-8-yl]-3-oxidanyl-butanamide, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Morstein, J, Amatuni, A, Schuster, A, Kuttenlochner, W, Ko, T, Groll, M, Adibekian, A, Renata, H, Trauner, D.H. | 登録日 | 2023-03-21 | 公開日 | 2023-12-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide. Angew.Chem.Int.Ed.Engl., 63, 2024
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8OI1
| Yeast 20S proteasome in complex with a photoswitchable cepafungin derivative (transCep4) | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | 著者 | Morstein, J, Amatuni, A, Schuster, A, Kuttenlochner, W, Ko, T, Groll, M, Adibekian, A, Renata, H, Trauner, D.H. | 登録日 | 2023-03-21 | 公開日 | 2023-12-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide. Angew.Chem.Int.Ed.Engl., 63, 2024
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6QPS
| Structural characterization of a mannuronic acid specific polysaccharide family 6 lyase enzyme from human gut microbiota | 分子名称: | ACETATE ION, CALCIUM ION, Polysaccharide Lyase Family 6 | 著者 | Fredslund, F, Stender, E.G.P, Svensson, B, Welner, D.H. | 登録日 | 2019-02-14 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.287 Å) | 主引用文献 | Structural and functional aspects of mannuronic acid-specific PL6 alginate lyase from the human gut microbeBacteroides cellulosilyticus. J.Biol.Chem., 294, 2019
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3LCR
| Thioesterase from Tautomycetin Biosynthhetic Pathway | 分子名称: | DIMETHYL SULFOXIDE, FORMIC ACID, Tautomycetin biosynthetic PKS | 著者 | Akey, D.L, Scaglione, J.B, Smith, J.L, Sherman, D.H. | 登録日 | 2010-01-11 | 公開日 | 2010-08-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase. Angew.Chem.Int.Ed.Engl., 49, 2010
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3NJE
| Structure of the Minor Pseudopilin XcpW from the Pseudomonas aeruginosa Type II Secretion System | 分子名称: | General secretion pathway protein J | 著者 | Franz, L.P, Dyer, D.H, Voulhoux, R, Forest, K.T. | 登録日 | 2010-06-17 | 公開日 | 2011-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of the minor pseudopilin XcpW from the Pseudomonas aeruginosa type II secretion system. Acta Crystallogr.,Sect.D, 67, 2011
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3MI9
| Crystal structure of HIV-1 Tat complexed with human P-TEFb | 分子名称: | Cell division protein kinase 9, Cyclin-T1, Protein Tat, ... | 著者 | Tahirov, T.H, Babayeva, N.D, Varzavand, K, Cooper, J.J, Sedore, S.C, Price, D.H. | 登録日 | 2010-04-09 | 公開日 | 2010-06-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of HIV-1 Tat complexed with human P-TEFb. Nature, 465, 2010
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3MAT
| E.COLI METHIONINE AMINOPEPTIDASE TRANSITION-STATE INHIBITOR COMPLEX | 分子名称: | COBALT (II) ION, METHIONINE AMINOPEPTIDASE, SODIUM ION, ... | 著者 | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | 登録日 | 1999-03-29 | 公開日 | 1999-06-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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1BMX
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1Q6K
| Cathepsin K complexed with t-butyl(1S)-1-cyclohexyl-2-oxoethylcarbamate | 分子名称: | Cathepsin K, SULFATE ION, TERT-BUTYL(1S)-1-CYCLOHEXYL-2-OXOETHYLCARBAMATE | 著者 | Catalano, J.G, Deaton, D.N, Furfine, E.S, Hassell, A.M, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M, Willard, D.H, Wright, L.L. | 登録日 | 2003-08-13 | 公開日 | 2004-03-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Exploration of the P1 SAR of aldehyde cathepsin K inhibitors Bioorg.Med.Chem.Lett., 14, 2004
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5CWW
| Crystal structure of the Chaetomium thermophilum heterotrimeric Nup82 NTD-Nup159 TAIL-Nup145N APD complex | 分子名称: | Nucleoporin NUP145N, Nucleoporin NUP159, Nucleoporin NUP82 | 著者 | Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A. | 登録日 | 2015-07-28 | 公開日 | 2015-09-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
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