6MJ5
| Crystal structure of Tdp1 catalytic domain in complex with compound XZ519 | 分子名称: | 1,2-ETHANEDIOL, 4-hydroxy-8-nitroquinoline-3-carboxylic acid, Tyrosyl-DNA phosphodiesterase 1 | 著者 | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S. | 登録日 | 2018-09-20 | 公開日 | 2019-07-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.853 Å) | 主引用文献 | Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening. Nucleic Acids Res., 47, 2019
|
|
6MJP
| LptB(E163Q)FGC from Vibrio cholerae | 分子名称: | 2-(2-ETHOXYETHOXY)ETHANOL, 6-cyclohexylhexyl beta-D-glucopyranoside, ABC transporter ATP-binding protein, ... | 著者 | Owens, T.W, Kahne, D, Kruse, A.C. | 登録日 | 2018-09-21 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural basis of unidirectional export of lipopolysaccharide to the cell surface. Nature, 567, 2019
|
|
6YDH
| |
5A9G
| Manganese Superoxide Dismutase from Sphingobacterium sp. T2 | 分子名称: | MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | 著者 | Rashid, G.M.M, Taylor, C.R, Liu, Y, Zhang, X, Rea, D, Fulop, V, Bugg, T.D.H. | 登録日 | 2015-07-21 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Identification of Manganese Superoxide Dismutase from Sphingobacterium Sp. T2 as a Novel Bacterial Enzyme for Lignin Oxidation. Acs Chem.Biol., 10, 2015
|
|
6YZ0
| Full length Open-form Sodium Channel NavMs F208L in complex with Cannabidiol (CBD) | 分子名称: | 2-[(1R,2R,5S)-5-methyl-2-(prop-1-en-2-yl)cyclohexyl]-5-pentylbenzene-1,3-diol, DODECAETHYLENE GLYCOL, HEGA-10, ... | 著者 | Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A. | 登録日 | 2020-05-06 | 公開日 | 2020-11-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cannabidiol interactions with voltage-gated sodium channels. Elife, 9, 2020
|
|
6V9V
| Structure of TRPA1 modified by Bodipy-iodoacetamide with bound calcium, LMNG | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily A member 1, ~{N}-[[2,2-bis(fluoranyl)-10,12-dimethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9,11-tetraen-4-yl]methyl]ethanamide | 著者 | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | 登録日 | 2019-12-16 | 公開日 | 2020-05-06 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Nature, 585, 2020
|
|
5A2G
| An esterase from anaerobic Clostridium hathewayi can hydrolyze aliphatic aromatic polyesters | 分子名称: | CARBOXYLIC ESTER HYDROLASE, PHOSPHATE ION | 著者 | Hromic, A, Pavkov Keller, T, Steinkellner, G, Gruber, K, Perz, V, Baumschlager, A, Bleymaier, K, Zitzenbacher, S, Zankel, A, Mayrhofer, C, Sinkel, C, Kueper, U, Schlegel, K.A, Ribitsch, D, Guebitz, G.M. | 登録日 | 2015-05-19 | 公開日 | 2016-02-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | An Esterase from Anaerobic Clostridium Hathewayi Can Hydrolyze Aliphatic-Aromatic Polyesters. Environ.Sci.Tech., 50, 2016
|
|
6V9A
| Agrobacterium tumefaciens ADP-Glucose pyrophosphorylase-S72D | 分子名称: | CITRIC ACID, GLYCEROL, Glucose-1-phosphate adenylyltransferase | 著者 | Zheng, Y, Alghamdi, M.A, Ballicora, M.A, Liu, D. | 登録日 | 2019-12-13 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Site-directed mutagenesis of Serine-72 reveals the location of the fructose 6-phosphate regulatory site of the Agrobacterium tumefaciens ADP-glucose pyrophosphorylase. Protein Sci., 31, 2022
|
|
6VB4
| HLA-B*15:02 complexed with a synthetic peptide | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ... | 著者 | Schutte, R.J, Li, D, Andring, J, McKenna, R, Ostrov, D.A. | 登録日 | 2019-12-18 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.334 Å) | 主引用文献 | HLA-B*15:02 complexed with a synthetic peptide To Be Published
|
|
6YU6
| Crystal structure of MhsT in complex with L-leucine | 分子名称: | DODECYL-BETA-D-MALTOSIDE, LEUCINE, SODIUM ION, ... | 著者 | Focht, D, Neumann, C, Lyons, J, Eguskiza Bilbao, A, Blunck, R, Malinauskaite, L, Schwarz, I.O, Javitch, J.A, Quick, M, Nissen, P. | 登録日 | 2020-04-25 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition. Embo J., 40, 2021
|
|
6Z3P
| Structure of EV71 in complex with a protective antibody 38-3-11A Fab | 分子名称: | SPHINGOSINE, VP1, VP2, ... | 著者 | Zhou, D, Fry, E.E, Ren, J, Stuart, D.I. | 登録日 | 2020-05-21 | 公開日 | 2020-09-02 | 最終更新日 | 2020-10-28 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71. Nat Commun, 11, 2020
|
|
6YYI
| Crystal structure of beta-D-xylosidase from Dictyoglomus thermophilum bound to beta-D-xylopyranose | 分子名称: | 1,2-ETHANEDIOL, Beta-xylosidase, CITRIC ACID, ... | 著者 | Lafite, P, Daniellou, R, Bretagne, D. | 登録日 | 2020-05-05 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Crystal structure of Dictyoglomus thermophilum beta-d-xylosidase DtXyl unravels the structural determinants for efficient notoginsenoside R1 hydrolysis. Biochimie, 181, 2020
|
|
6Z4B
| Crystal Structure of EGFR-T790M/V948R in Complex with Osimertinib and EAI045 | 分子名称: | (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, SULFATE ION, ... | 著者 | Niggenaber, J, Mueller, M.P, Rauh, D. | 登録日 | 2020-05-25 | 公開日 | 2020-11-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Complex Crystal Structures of EGFR with Third-Generation Kinase Inhibitors and Simultaneously Bound Allosteric Ligands. Acs Med.Chem.Lett., 11, 2020
|
|
5DAJ
| Crystal structure of NalD, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa | 分子名称: | NalD | 著者 | Chen, W.Z, Wang, D, Huang, S.Q, Hu, Q.Y, Liu, X.C, Gan, J.H, Chen, H. | 登録日 | 2015-08-20 | 公開日 | 2016-04-20 | 最終更新日 | 2023-04-12 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosa Mol.Microbiol., 100, 2016
|
|
6UZQ
| |
1MDT
| |
6ZKP
| Native complex I, open1 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE MONOPHOSPHATE, ... | 著者 | Kampjut, D, Sazanov, L.A. | 登録日 | 2020-06-30 | 公開日 | 2020-10-07 | 最終更新日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The coupling mechanism of mammalian respiratory complex I. Science, 370, 2020
|
|
6ZLC
| Non-specific dsRNA recognition by wildtype H7N1 RNA-binding domain | 分子名称: | NITRATE ION, Non-structural protein 1, RNA (5'-R(*AP*GP*AP*CP*AP*GP*CP*AP*UP*UP*AP*UP*GP*CP*UP*GP*UP*CP*U)-3'), ... | 著者 | Coste, F, Wacquiez, A, Marc, D, Castaing, B. | 登録日 | 2020-06-30 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 12, 2020
|
|
5CR1
| Crystal structure of TTR/resveratrol/T4 complex | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, RESVERATROL, Transthyretin | 著者 | Zanotti, G, Florio, P, Folli, C, Cianci, M, Del Rio, D, Berni, R. | 登録日 | 2015-07-22 | 公開日 | 2015-10-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.545 Å) | 主引用文献 | Transthyretin Binding Heterogeneity and Anti-amyloidogenic Activity of Natural Polyphenols and Their Metabolites. J.Biol.Chem., 290, 2015
|
|
6YWP
| Structure of apo-CutA | 分子名称: | CutA, MAGNESIUM ION | 著者 | Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M. | 登録日 | 2020-04-29 | 公開日 | 2020-08-05 | 最終更新日 | 2020-09-30 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine. Nucleic Acids Res., 48, 2020
|
|
1MZN
| CRYSTAL STRUCTURE at 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO THE SYNTHETIC AGONIST COMPOUND BMS 649 AND A COACTIVATOR PEPTIDE | 分子名称: | 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID, Nuclear receptor coactivator 2, RXR retinoid X receptor | 著者 | Egea, P.F, Mitschler, A, Moras, D. | 登録日 | 2002-10-09 | 公開日 | 2002-10-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular Recognition of Agonist Ligands by RXRs MOL.ENDOCRINOL., 16, 2002
|
|
6YUP
| Heterotetrameric structure of the rBAT-b(0,+)AT1 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neutral and basic amino acid transport protein rBAT, ... | 著者 | Wu, D, Safarian, S, Michel, H. | 登録日 | 2020-04-27 | 公開日 | 2021-01-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6MTO
| Crystal structure of VRC42.01 Fab in complex with T117-F MPER scaffold | 分子名称: | Antibody VRC42.01 Fab heavy chain, Antibody VRC42.01 Fab light chain, VRC42 epitope T117-F scaffold | 著者 | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D. | 登録日 | 2018-10-21 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.634 Å) | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity, 50, 2019
|
|
6YXY
| State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate | 分子名称: | 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N. | 登録日 | 2020-05-04 | 公開日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis. Mol.Cell, 79, 2020
|
|
6MTR
| Crystal structure of VRC43.01 Fab | 分子名称: | Antibody VRC43.01 Fab heavy chain, Antibody VRC43.01 Fab light chain | 著者 | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D. | 登録日 | 2018-10-21 | 公開日 | 2019-03-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity, 50, 2019
|
|