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PDB: 22172 件

7YL0
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Structure of hIAPP-TF-type2
分子名称: Islet amyloid polypeptide
著者Li, D, Zhang, X, Wang, Y, Zhu, P.
登録日2022-07-25
公開日2022-12-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
7YL7
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Structure of hIAPP-TF-type3
分子名称: Islet amyloid polypeptide
著者Li, D, Zhang, X.
登録日2022-07-25
公開日2022-12-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
7YM0
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Lysoplasmalogen-specific phospholipase D (LyPls-PLD) with Ca2+
分子名称: CALCIUM ION, Lysoplasmalogenase
著者Yasutake, Y, Sakasegawa, S, Sugimori, D, Murayama, K.
登録日2022-07-27
公開日2023-01-04
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D from Thermocrispum sp. RD004668.
Biosci.Biotechnol.Biochem., 87, 2022
6ZEZ
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Keap1 kelch domain bound to a small molecule inhibitor of the Keap1-Nrf2 protein-protein interaction
分子名称: 1-[3-[(1~{R},3~{S})-3-[(2~{S})-2-butylpyrrolidin-1-yl]carbonylcyclohexyl]phenyl]-5-cyclopropyl-pyrazole-4-carboxylic acid, Kelch-like ECH-associated protein 1
著者Narayanan, D, Bach, A, Gajhede, M.
登録日2020-06-16
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
J.Med.Chem., 64, 2021
6ZF8
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Keap1 kelch domain bound to a small molecule inhibitor of the Keap1-Nrf2 protein-protein interaction
分子名称: 1-[3-[2-hydroxy-2-oxoethyl-(3-methoxyphenyl)sulfonyl-amino]phenyl]-5-[(1~{S},2~{S})-2-phenylcyclopropyl]pyrazole-4-carboxylic acid, DIMETHYL SULFOXIDE, Kelch-like ECH-associated protein 1, ...
著者Narayanan, D, Bach, A, Gajhede, M.
登録日2020-06-16
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
J.Med.Chem., 64, 2021
7YKW
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Structure of hIAPP fibril at 3.6 Angstroms resolution
分子名称: Islet amyloid polypeptide
著者Li, D, Zhang, X, Wang, Y, Zhu, P.
登録日2022-07-25
公開日2023-01-18
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
4FC7
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Studies on DCR shed new light on peroxisomal beta-oxidation: Crystal structure of the ternary complex of pDCR
分子名称: COENZYME A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Peroxisomal 2,4-dienoyl-CoA reductase
著者Hua, T, Wu, D, Wang, J, Shaw, N, Liu, Z.-J.
登録日2012-05-24
公開日2012-07-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal beta-oxidation of unsaturated fatty acids
J.Biol.Chem., 287, 2012
4FF9
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Crystal Structure of cysteinylated WT SOD1.
分子名称: COPPER (II) ION, CYSTEINE, Superoxide dismutase [Cu-Zn], ...
著者Auclair, J.R, Brodkin, H.R, D'Aquino, J.A, Ringe, D, Petsko, G.A, Agar, J.N.
登録日2012-05-31
公開日2013-09-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5003 Å)
主引用文献Structural consequences of cysteinylation of cu/zn-superoxide dismutase.
Biochemistry, 52, 2013
7Y0D
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Cryo-EM structure of the Mycobacterium smegmatis DNA integrity scanning protein (MsDisA).
分子名称: DNA integrity scanning protein DisA
著者Gautam, S, Vinothkumar, K.R, Chatterji, D.
登録日2022-06-04
公開日2023-02-08
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Regulatory mechanisms of c-di-AMP synthase (MsDisA) protein from Mycobacterium smegmatis revealed by a structure - function analysis.
Protein Sci., 32, 2023
4FHB
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Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)
分子名称: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Oyen, D.
登録日2012-06-06
公開日2013-04-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli.
Biochim.Biophys.Acta, 1834, 2013
4FGQ
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Legionella pneumophila LapG
分子名称: Periplasmic protein
著者Chatterjee, D, Boyd, C.D, O'Toole, G.A, Sondermann, H.
登録日2012-06-04
公開日2012-06-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.645 Å)
主引用文献Structural characterization of a conserved, calcium-dependent periplasmic protease from Legionella pneumophila.
J.Bacteriol., 194, 2012
4FKA
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High resolution structure of the manganese derivative of insulin
分子名称: Insulin A chain, Insulin B chain, MANGANESE (II) ION, ...
著者Prugovecki, B, Pulic, I, Toth, M, Matkovic-Calogovic, D.
登録日2012-06-13
公開日2013-02-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献High Resolution Structure of the Manganese Derivative of Insulin
Croat.Chem.Acta, 85, 2012
7YCX
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The structure of INTAC-PEC complex
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ...
著者Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y.
登録日2022-07-02
公開日2023-03-15
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (4.18 Å)
主引用文献Structural basis of INTAC-regulated transcription.
Protein Cell, 14, 2023
4FC6
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Studies on DCR shed new light on peroxisomal beta-oxidation: Crystal structure of the ternary complex of pDCR
分子名称: HEXANOYL-COENZYME A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Peroxisomal 2,4-dienoyl-CoA reductase
著者Hua, T, Wu, D, Wang, J, Shaw, N, Liu, Z.-J.
登録日2012-05-24
公開日2012-07-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal beta-oxidation of unsaturated fatty acids
J.Biol.Chem., 287, 2012
7YDQ
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BU of 7ydq by Molmil
Structure of PfNT1(Y190A)-GFP in complex with GSK4
分子名称: 5-methyl-N-[2-(2-oxidanylideneazepan-1-yl)ethyl]-2-phenyl-1,3-oxazole-4-carboxamide, Nucleoside transporter 1,Green fluorescent protein
著者Wang, C, Yu, L.Y, Li, J.L, Ren, R.B, Deng, D.
登録日2022-07-04
公開日2023-04-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
7XX6
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Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
分子名称: CALCIUM ION, DNA (169-MER), Histone H1.0, ...
著者Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A.
登録日2022-05-28
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
To Be Published
7XVM
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Crystal Structure of Nucleosome-H5 Linker Histone Assembly (sticky-169a DNA fragment)
分子名称: CALCIUM ION, CHLORIDE ION, DNA (169-MER), ...
著者Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A.
登録日2022-05-24
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
To Be Published
7XVL
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Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment)
分子名称: DNA (169-MER), Histone H1.0, Histone H2A type 1-B/E, ...
著者Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A.
登録日2022-05-24
公開日2023-05-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.506 Å)
主引用文献Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment)
To Be Published
7XX5
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Crystal Structure of Nucleosome-H1.3 Linker Histone Assembly (sticky-169a DNA fragment)
分子名称: CALCIUM ION, DNA (169-MER), Histone H1.3, ...
著者Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A.
登録日2022-05-28
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
To Be Published
7QTR
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GB1 in mammalian cells, 50 uM
分子名称: Immunoglobulin G-binding protein G
著者Gerez, J.A, Prymaczok, N.C, Kadavath, H, Gosh, D, Butikofer, M, Guntert, P, Riek, R.
登録日2022-01-15
公開日2022-12-21
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Protein structure determination in human cells by in-cell NMR and a reporter system to optimize protein delivery or transexpression.
Commun Biol, 5, 2022
7QHA
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Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in amphipol
分子名称: Megabody c7HopQ, Putative TRAP-type C4-dicarboxylate transport system, large permease component, ...
著者North, R.A, Davies, J.S, Morado, D, Dobson, R.C.J.
登録日2021-12-11
公開日2022-12-21
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
7QTS
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GB1 in mammalian cells, 10 uM
分子名称: Immunoglobulin G-binding protein G
著者Gerez, J.A, Prymaczok, N.C, Kadavath, H, Gosh, D, Butikofer, M, Guntert, P, Riek, R.
登録日2022-01-15
公開日2022-12-21
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Protein structure determination in human cells by in-cell NMR and a reporter system to optimize protein delivery or transexpression.
Commun Biol, 5, 2022
7QFJ
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Crystal structure of S-layer protein SlpX from Lactobacillus acidophilus, domain II (aa 194-362)
分子名称: SlpX
著者Sagmeister, T, Pavkov-Keller, T, Buhlheller, C, Baek, M, Read, R, Baker, D.
登録日2021-12-06
公開日2022-12-21
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The molecular architecture of Lactobacillus S-layer: Assembly and attachment to teichoic acids.
Proc.Natl.Acad.Sci.USA, 121, 2024
7QOQ
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Crystal structure of Mycobacterium hassiacum glucosyl-3-phosphoglycerate synthase at pH 8.5 in complex with UMP and Magnesium
分子名称: CHLORIDE ION, Glucosyl-3-phosphoglycerate synthase, MAGNESIUM ION, ...
著者Silva, A, Barbosa Pereira, P.J, Macedo-Ribeiro, S, Costa, D.
登録日2021-12-27
公開日2023-01-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure of Mycobacterium hassiacum glucosyl-3-phosphoglycerate synthase at pH 8.5 in complex with UMP and Magnesium
To Be Published
7RB1
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Isocitrate Lyase-1 from Mycobacterium tuberculosis covalently modified by 5-descarboxy-5-nitro-D-isocitric acid
分子名称: (3E)-3-(hydroxyimino)propanoic acid, GLYCEROL, GLYOXYLIC ACID, ...
著者Krieger, I.V, Mellott, D, Meek, T, Sacchettini, J.C.
登録日2021-07-05
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2 R ,3 S )-2-Hydroxy-3-(nitromethyl)succinic acid.
J.Am.Chem.Soc., 143, 2021

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件を2024-07-10に公開中

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