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PDB: 53012 件

7N07
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Crystal structure of the apo 3D6 antibody fragment
分子名称: Fab 3D6 heavy chain, Fab 3D6 light chain, SULFATE ION
著者Cook, J.D, Lee, J.E.
登録日2021-05-25
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies.
Commun Biol, 5, 2022
7B02
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Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid
分子名称: 4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Fata, F, Silvestri, I, Williams, D.L, Angelucci, F.
登録日2020-11-18
公開日2021-05-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments.
Acs Infect Dis., 7, 2021
3HOS
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BU of 3hos by Molmil
Crystal structure of the mariner Mos1 paired end complex with Mg
分子名称: MAGNESIUM ION, Mos1 NTS inverted repeat DNA, Mos1 TS inverted repeat DNA, ...
著者Richardson, J.M, Walkinshaw, M.D.
登録日2009-06-03
公開日2009-09-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular architecture of the Mos1 paired-end complex: the structural basis of DNA transposition in a eukaryote
Cell(Cambridge,Mass.), 138, 2009
7KP7
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asymmetric mTNF-alpha hTNFR1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Tumor necrosis factor, ...
著者Arakaki, T.L, Fox III, D, Edwards, T.E, Foley, A, Ceska, T.
登録日2020-11-10
公開日2021-01-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.
Nat Commun, 12, 2021
6V5N
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BU of 6v5n by Molmil
EGFR(T790M/V948R) in complex with LN2084
分子名称: 3-[4-(4-fluorophenyl)-5-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-imidazol-2-yl]propan-1-ol, CHLORIDE ION, Epidermal growth factor receptor
著者Heppner, D.E, Eck, M.J.
登録日2019-12-04
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for EGFR Mutant Inhibition by Trisubstituted Imidazole Inhibitors.
J.Med.Chem., 63, 2020
7PQ1
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Ligand-free crystal structure of a staphylococcal orthologue of CYP134A1
分子名称: Cytochrome P450 protein, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE
著者Snee, M, Levy, C, Leys, D, Katariya, M, Munro, A.W.
登録日2021-09-15
公開日2022-09-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Crystal structure of a staphylococcal orthologue of CYP134A1 (CYPX) in complex with Cyclo-L-leucyl-L-leucine
To Be Published
8CF8
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BU of 8cf8 by Molmil
Eravacycline bound to the 30S head
分子名称: 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S7, ...
著者Paternoga, H, Koller, T.O, Beckert, B, Wilson, D.N.
登録日2023-02-03
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
5K19
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BU of 5k19 by Molmil
Crystal structure of WD repeat-containing protein 20
分子名称: GLYCEROL, SULFATE ION, WD repeat-containing protein 20
著者Li, H, D'Andrea, A.D, Zheng, N.
登録日2016-05-17
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
6B7H
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Structure of mGluR3 with an agonist
分子名称: (1S,2S,4S,5R,6S)-2-amino-4-[(3-methoxybenzene-1-carbonyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Monn, J.A, Clawson, D.K.
登録日2017-10-04
公開日2018-04-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Synthesis and Pharmacological Characterization of C4beta-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu3Receptor Agonist.
J. Med. Chem., 61, 2018
3I6M
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3D Structure of Torpedo californica acetylcholinesterase complexed with N-piperidinopropyl-galanthamine
分子名称: (4aS,6R,8aS)-3-methoxy-11-(3-piperidin-1-ylpropyl)-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lamba, D, Bartolucci, C.
登録日2009-07-07
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Probing Torpedo californica acetylcholinesterase catalytic gorge with two novel bis-functional galanthamine derivatives.
J.Med.Chem., 53, 2010
7N58
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BU of 7n58 by Molmil
Structure of AtAtm3 in the inward-facing conformation
分子名称: ABC transporter B family member 25, mitochondrial
著者Fan, C, Rees, D.C.
登録日2021-06-05
公開日2022-04-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters.
Elife, 11, 2022
7PL9
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BU of 7pl9 by Molmil
Cryo-EM structure of Bestrhodopsin (rhodopsin-rhodopsin-bestrophin) complex
分子名称: RETINAL, Rhodopsin
著者Matzov, D, Kaczmarczyk, I, Shalev-Benami, M.
登録日2021-08-29
公開日2022-07-06
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels.
Nat.Struct.Mol.Biol., 29, 2022
5K2H
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BU of 5k2h by Molmil
Structure of GNNQQNY from yeast prion Sup35 in space group P212121 determined by MicroED
分子名称: Eukaryotic peptide chain release factor GTP-binding subunit
著者Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2016-05-18
公開日2016-09-14
最終更新日2024-03-06
実験手法ELECTRON CRYSTALLOGRAPHY (1.05 Å)
主引用文献Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.
Proc.Natl.Acad.Sci.USA, 113, 2016
7AFK
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BU of 7afk by Molmil
Bacterial 30S ribosomal subunit assembly complex state D (head domain)
分子名称: 16SrRNA (head domain of the 30S ribosome), 30S ribosomal protein S10, 30S ribosomal protein S13, ...
著者Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
登録日2020-09-19
公開日2021-07-07
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
5K3I
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BU of 5k3i by Molmil
Crystal structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans complexed with FAD and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A.
登録日2016-05-19
公開日2016-08-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.683 Å)
主引用文献Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans.
Proc.Natl.Acad.Sci.USA, 113, 2016
6MNC
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BU of 6mnc by Molmil
CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRONE
分子名称: (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one, DI(HYDROXYETHYL)ETHER, Estradiol 17-beta-dehydrogenase 1
著者Li, T, Stephen, P, Zhu, D.W, Lin, S.X.
登録日2018-10-01
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of human 17 beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP+reveal the mechanism of substrate inhibition.
Febs J., 286, 2019
6Y1A
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BU of 6y1a by Molmil
Amyloid fibril structure of islet amyloid polypeptide
分子名称: AMINO GROUP, Islet amyloid polypeptide
著者Roeder, C, Kupreichyk, T, Gremer, L, Schaefer, L.U, Pothula, K.R, Ravelli, R.B.G, Willbold, D, Hoyer, W, Schroder, G.F.
登録日2020-02-11
公開日2020-03-04
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-beta fibrils.
Nat.Struct.Mol.Biol., 27, 2020
5MUB
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BU of 5mub by Molmil
ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (CG05)
分子名称: ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, triple-helical peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,triple-helical peptide containing the citrullinated C1 epitope of collagen type II
著者Dobritzsch, D, Holmdahl, R, Ge, C.
登録日2017-01-13
公開日2017-07-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
5MVT
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Crystal structure of an A-DNA dodecamer featuring an alternating pyrimidine-purine sequence
分子名称: COBALT (III) ION, DNA
著者Hardwick, J.S, Ptchelkine, D, Phillips, S.E.V, Brown, T.
登録日2017-01-17
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.896 Å)
主引用文献5-Formylcytosine does not change the global structure of DNA.
Nat. Struct. Mol. Biol., 24, 2017
5CMP
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human FLRT3 LRR domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat transmembrane protein FLRT3
著者Lu, Y, Salzman, G, Arac, D.
登録日2015-07-17
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion.
Structure, 23, 2015
4XS1
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BU of 4xs1 by Molmil
Salmonella typhimurium AhpC T43V mutant
分子名称: Alkyl hydroperoxide reductase subunit C, CHLORIDE ION, POTASSIUM ION, ...
著者Perkins, A, Nelson, K, Parsonage, D, Poole, L, Karplus, P.A.
登録日2015-01-21
公開日2016-01-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Experimentally Dissecting the Origins of Peroxiredoxin Catalysis.
Antioxid.Redox Signal., 28, 2018
5C0R
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BU of 5c0r by Molmil
Crystal Structure of a Generation 3 Influenza Hemagglutinin Stabilized Stem Complexed with the Broadly Neutralizing Antibody C179
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C179 Fab heavy chain, ...
著者Boyington, J.C, kwong, P.D, Nabel, G.J, Mascola, J.R.
登録日2015-06-12
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.188 Å)
主引用文献Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection.
Nat. Med., 21, 2015
5G2T
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BU of 5g2t by Molmil
BT1596 in complex with its substrate 4,5 unsaturated uronic acid alpha 1,4 D-Glucosamine-2-N, 6-O-disulfate
分子名称: 1,2-ETHANEDIOL, 2-O GLYCOSAMINOGLYCAN SULFATASE, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid, ...
著者Cartmell, A, Lowe, E.C, Basle, A, Crouch, L.I, Czjzek, M, Turnbull, J, Henrissat, B, Terrapon, N, Thomas, S, Murray, H, Firbank, S.J, Bolam, D.N.
登録日2016-04-13
公開日2017-05-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6UW7
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The crystal structure of FbiA from Mycobacterium smegmatis, Dehydro-F420-0 bound form
分子名称: 2-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-[2,4,8-tris(oxidanylidene)-1,9-dihydropyrimido[4,5-b]quinolin-10-yl]pentoxy]phosphoryl]oxyprop-2-enoic acid, CALCIUM ION, GLYCEROL, ...
著者Grinter, R, Gillett, D, Cordero, P.R.F, Izore, T, Greening, C.
登録日2019-11-04
公開日2020-05-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.342 Å)
主引用文献Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria.
mSystems, 5, 2020
7N1S
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Crystal Structure Analysis of Xac Nucleotide Pyrophosphatase/Phosphodiesterase
分子名称: Phosphodiesterase-nucleotide pyrophosphatase, TETRAETHYLENE GLYCOL, ZINC ION
著者Fernandez, D, Li, L, Brown, J.A, Carozza, J.A.
登録日2021-05-28
公開日2022-06-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling.
Proc.Natl.Acad.Sci.USA, 119, 2022

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