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PDB: 5 件

6BP4
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BU of 6bp4 by Molmil
Structure of the S. pombe Clr4 catalytic domain bound to SAM
分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific, S-ADENOSYLMETHIONINE, ...
著者Currie, M.A, Moazed, D.
登録日2017-11-21
公開日2018-07-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7701 Å)
主引用文献Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability.
Nature, 560, 2018
6BOX
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BU of 6box by Molmil
Structure of the S. pombe Clr4 catalytic domain bound to SAH
分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Currie, M.A, Moazed, D.
登録日2017-11-21
公開日2018-07-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.412 Å)
主引用文献Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability.
Nature, 560, 2018
4FL4
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BU of 4fl4 by Molmil
Scaffoldin conformation and dynamics revealed by a ternary complex from the Clostridium thermocellum cellulosome
分子名称: CALCIUM ION, Cellulosome anchoring protein cohesin region, Glycoside hydrolase family 9, ...
著者Currie, M.A, Adams, J.J, Faucher, F, Bayer, E.A, Jia, Z, Smith, S.P, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2012-06-14
公開日2012-06-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Scaffoldin Conformation and Dynamics Revealed by a Ternary Complex from the Clostridium thermocellum Cellulosome.
J.Biol.Chem., 287, 2012
3KCP
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BU of 3kcp by Molmil
Crystal structure of interacting Clostridium thermocellum multimodular components
分子名称: CALCIUM ION, CHLORIDE ION, Cellulosomal-scaffolding protein A, ...
著者Adams, J.J, Currie, M.A, Bayer, E.A, Jia, Z, Smith, S.P.
登録日2009-10-21
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Insights into Higher-Order Organization of the Cellulosome Revealed by a Dissect-and-Build Approach: Crystal Structure of Interacting Clostridium thermocellum Multimodular Components
J.Mol.Biol., 396, 2010
4AQC
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BU of 4aqc by Molmil
Triazolopyridine-based Inhibitor of Janus Kinase 2
分子名称: 8-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine, SULFATE ION, TYROSINE-PROTEIN KINASE JAK2
著者Dugan, B.J, Gingrich, D.E, Mesaros, E.F, Milkiewicz, K.L, Curry, M.A, Zulli, A.L, Dobrzanski, P, Serdikoff, C, Jan, M, Angeles, T.S, Albom, M.S, Mason, J.L, Aimone, L.D, Meyer, S.L, Huang, Z, Wells-Knecht, K.J, Ator, M.A, Ruggeri, B.A, Dorsey, B.D.
登録日2012-04-16
公開日2012-04-25
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5-A]Pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of Cep-33779.
J.Med.Chem., 55, 2012

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件を2024-07-31に公開中

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