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PDB: 56 件
4L0E
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BU of 4l0e by Molmil
Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis (heme-coordinated expression tag)
分子名称: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Cryle, M.J.
登録日2013-05-31
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cytochrome p450sky interacts directly with the nonribosomal Peptide synthetase to generate three amino Acid precursors in skyllamycin biosynthesis.
Acs Chem.Biol., 8, 2013
4L0F
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BU of 4l0f by Molmil
Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis (open active site)
分子名称: 1,2-ETHANEDIOL, P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Cryle, M.J.
登録日2013-05-31
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cytochrome p450sky interacts directly with the nonribosomal Peptide synthetase to generate three amino Acid precursors in skyllamycin biosynthesis.
Acs Chem.Biol., 8, 2013
5EX9
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BU of 5ex9 by Molmil
Structure of P450 StaF from glycopeptide antibiotic A47934 biosynthesis; glycerol cryo
分子名称: Cytochrome P450, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE
著者Cryle, M.J, Ulrich, V.
登録日2015-11-23
公開日2017-01-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934.
Beilstein J Org Chem, 12, 2016
5EX8
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BU of 5ex8 by Molmil
Structure of P450 StaF from glycopeptide antibiotic A47934 biosynthesis; ethylene glycol cryo
分子名称: 1,2-ETHANEDIOL, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Cryle, M.J, Ulrich, V.
登録日2015-11-23
公開日2017-01-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934.
Beilstein J Org Chem, 12, 2016
5EX6
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BU of 5ex6 by Molmil
Structure of P450 StaH from glycopeptide antibiotic A47934 biosynthesis
分子名称: 1,2-ETHANEDIOL, Cytochrome P450, GLYCEROL, ...
著者Cryle, M.J, Ulrich, V.
登録日2015-11-23
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH.
Mol Biosyst, 12, 2016
3MGX
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BU of 3mgx by Molmil
Crystal Structure of P450 OxyD that is involved in the Biosynthesis of Vancomycin-type Antibiotics
分子名称: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative P450 monooxygenase
著者Cryle, M.J, Schlichting, I.
登録日2010-04-07
公開日2010-06-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of oxyd, a cytochrome p450 involved in {beta}-hydroxytyrosine formation in vancomycin biosynthesis
J.Biol.Chem., 285, 2010
3O1A
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BU of 3o1a by Molmil
Structure of OxyE (CYP165D3), a Cytochrome P450 Involved in Teicoplanin Biosynthesis
分子名称: Oxy protein, PROTOPORPHYRIN IX CONTAINING FE
著者Cryle, M.J, Schlichting, I.
登録日2010-07-21
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural characterization of CYP165D3, a cytochrome P450 involved in phenolic coupling in teicoplanin biosynthesis.
Arch.Biochem.Biophys., 507, 2011
3NC3
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BU of 3nc3 by Molmil
CYP134A1 structure with a closed substrate binding loop
分子名称: Cytochrome P450 cypX, GLYCEROL, MAGNESIUM ION, ...
著者Cryle, M.J, Schlichting, I.
登録日2010-06-04
公開日2010-08-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.
Biochemistry, 49, 2010
3NC6
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BU of 3nc6 by Molmil
CYP134A1 1-phenylimidazole bound structure
分子名称: 1-phenyl-1H-imidazole, Cytochrome P450 cypX, MAGNESIUM ION, ...
著者Cryle, M.J, Schlichting, I.
登録日2010-06-04
公開日2010-08-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.
Biochemistry, 49, 2010
3NC7
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BU of 3nc7 by Molmil
CYP134A1 2-phenylimidazole bound structure
分子名称: 2-phenyl-1H-imidazole, Cytochrome P450 cypX, MAGNESIUM ION, ...
著者Cryle, M.J, Schlichting, I.
登録日2010-06-04
公開日2010-08-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.
Biochemistry, 49, 2010
3NC5
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BU of 3nc5 by Molmil
CYP134A1 structure with an open substrate binding loop
分子名称: Cytochrome P450 cypX, GLYCEROL, MAGNESIUM ION, ...
著者Cryle, M.J, Schlichting, I.
登録日2010-06-04
公開日2010-08-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.
Biochemistry, 49, 2010
3EJE
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BU of 3eje by Molmil
Crystal Structure of P450BioI in complex with octadec-9Z-enoic acid ligated Acyl Carrier Protein
分子名称: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Cryle, M.J, Schlichting, I.
登録日2008-09-18
公開日2008-10-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EJB
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BU of 3ejb by Molmil
Crystal Structure of P450BioI in complex with tetradecanoic acid ligated Acyl Carrier Protein
分子名称: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, CHLORIDE ION, ...
著者Cryle, M.J, Schlichting, I.
登録日2008-09-18
公開日2008-10-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EJD
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BU of 3ejd by Molmil
Crystal Structure of P450BioI in complex with hexadec-9Z-enoic acid ligated Acyl Carrier Protein
分子名称: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, CHLORIDE ION, ...
著者Cryle, M.J, Schlichting, I.
登録日2008-09-18
公開日2008-10-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4TVF
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BU of 4tvf by Molmil
OxyB from Actinoplanes teichomyceticus
分子名称: OxyB, PROTOPORPHYRIN IX CONTAINING FE
著者Haslinger, K, Cryle, M.J.
登録日2014-06-26
公開日2014-11-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cytochrome P450 OxyBtei Catalyzes the First Phenolic Coupling Step in Teicoplanin Biosynthesis.
Chembiochem, 15, 2014
4TX2
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BU of 4tx2 by Molmil
Crystal structure of the X-domain from teicoplanin biosynthesis
分子名称: Non-ribosomal peptide synthetase
著者Peschke, M, Haslinger, K, Cryle, M.J.
登録日2014-07-02
公開日2015-02-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis.
Nature, 521, 2015
5HH3
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BU of 5hh3 by Molmil
OxyA from Actinoplanes teichomyceticus
分子名称: ACETATE ION, GLYCEROL, OxyA protein, ...
著者Haslinger, K, Cryle, M.J.
登録日2016-01-09
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of OxyAtei : completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascade.
Febs Lett., 590, 2016
6M7L
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BU of 6m7l by Molmil
Complex of OxyA with the X-domain from GPA biosynthesis
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase, Putative non-ribosomal peptide synthetase
著者Greule, A, Izore, T, Tailhades, J, Peschke, M, Schoppet, M, Ahmed, I, Kulik, A, Adamek, M, Ziemert, N, De Voss, J, Stegmann, E, Cryle, M.J.
登録日2018-08-20
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.648297 Å)
主引用文献Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics.
Nat Commun, 10, 2019
8U3N
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BU of 8u3n by Molmil
Structure of P450Blt from Micromonospora sp. MW-13
分子名称: Cytochrome P450-SU1, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Hansen, M.H, Cryle, M.J, Zhao, Y.
登録日2023-09-08
公開日2024-01-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis
Acs Catalysis, 2024
8UKZ
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BU of 8ukz by Molmil
Structure of P450Blt from Micromonospora sp. MW-13 with E238A Mutation
分子名称: ACETATE ION, Cytochrome P450-SU1, DI(HYDROXYETHYL)ETHER, ...
著者Hansen, M.H, Cryle, M.J.
登録日2023-10-15
公開日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis
Acs Catalysis, 2024
8U2M
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BU of 8u2m by Molmil
Structure of P450Blt from Micromonospora sp. MW-13 in Complex with Biarylitide
分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, ACETATE ION, Cytochrome P450-SU1, ...
著者Hansen, M.H, Cryle, M.J.
登録日2023-09-06
公開日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis
Acs Catalysis, 2024
2MR8
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BU of 2mr8 by Molmil
holo structure of the Peptidyl Carrier Protein Domain 7 of the teicoplanin producing Non-ribosomal peptide synthetase
分子名称: Non-ribosomal peptide synthetase
著者Haslinger, K, Maximowitsch, E, Redfield, C, Cryle, M.J.
登録日2014-07-02
公開日2015-01-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis.
Proteins, 83, 2015
2MR7
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BU of 2mr7 by Molmil
apo structure of the Peptidyl Carrier Protein Domain 7 of the teicoplanin producing Non-ribosomal peptide synthetase
分子名称: Non-ribosomal peptide synthetase
著者Haslinger, K, Maximowitsch, E, Redfield, C, Cryle, M.J.
登録日2014-07-02
公開日2015-01-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis.
Proteins, 83, 2015
3CVY
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BU of 3cvy by Molmil
Drosophila melanogaster (6-4) photolyase bound to repaired ds DNA
分子名称: DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T.
登録日2008-04-20
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and mechanism of a DNA (6-4) photolyase.
Angew.Chem.Int.Ed.Engl., 47, 2008
3CVU
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BU of 3cvu by Molmil
Drosophila melanogaster (6-4) photolyase bound to ds DNA with a T-T (6-4) photolesion
分子名称: DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T.
登録日2008-04-20
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure and mechanism of a DNA (6-4) photolyase.
Angew.Chem.Int.Ed.Engl., 47, 2008

 

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