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PDB: 28 件

7U0H
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BU of 7u0h by Molmil
State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model
分子名称: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2022-02-18
公開日2022-12-14
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
8V84
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BU of 8v84 by Molmil
60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map)
分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
登録日2023-12-04
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8V83
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BU of 8v83 by Molmil
60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map)
分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
登録日2023-12-04
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8V87
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BU of 8v87 by Molmil
60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map)
分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
登録日2023-12-04
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
7NAD
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BU of 7nad by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb4 local refinement model
分子名称: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L17-A, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-21
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7NAC
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BU of 7nac by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model
分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-21
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7NAF
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BU of 7naf by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb1-MTD local model
分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-21
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R72
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BU of 7r72 by Molmil
State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model
分子名称: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-24
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R7A
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BU of 7r7a by Molmil
State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model
分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-24
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
8V85
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BU of 8v85 by Molmil
60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Low-pass filtered locally refined map)
分子名称: ATP-dependent RNA helicase DBP10
著者Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
登録日2023-12-04
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
6WMF
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BU of 6wmf by Molmil
Human Sun2-KASH5 complex
分子名称: POTASSIUM ION, Protein KASH5, SUN domain-containing protein 2
著者Cruz, V.E, Schwartz, T.U.
登録日2020-04-21
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
J.Mol.Biol., 432, 2020
6WME
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BU of 6wme by Molmil
Human Sun2-KASH3 complex
分子名称: Nesprin-3, POTASSIUM ION, SUN domain-containing protein 2
著者Cruz, V.E, Schwartz, T.U.
登録日2020-04-21
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
J.Mol.Biol., 432, 2020
6WMG
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BU of 6wmg by Molmil
Human Sun2 (500-717)
分子名称: POTASSIUM ION, SUN domain-containing protein 2
著者Cruz, V.E, Schwartz, T.U.
登録日2020-04-21
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
J.Mol.Biol., 432, 2020
5JJ7
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BU of 5jj7 by Molmil
Fic-1 (aa134 - 508 E274G) from C. elegans
分子名称: Adenosine monophosphate-protein transferase FICD homolog, SULFATE ION
著者Cruz, V.E, Schwartz, T.U.
登録日2016-04-22
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.749 Å)
主引用文献Fic-1 (aa134 - 508 E274G) from C. elegans
To be published
5JJ6
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BU of 5jj6 by Molmil
Fic-1 (aa134 - 508) from C. elegans
分子名称: Adenosine monophosphate-protein transferase FICD homolog, SULFATE ION
著者Cruz, V.E, Schwartz, T.U.
登録日2016-04-22
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.907 Å)
主引用文献Fic-1 dimer
To be published
7R6K
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BU of 7r6k by Molmil
State E2 nucleolar 60S ribosomal intermediate - Model for Noc2/Noc3 region
分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-22
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R7C
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BU of 7r7c by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - L1 stalk local model
分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-24
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R6Q
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BU of 7r6q by Molmil
State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model
分子名称: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-23
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R7O
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BU of 7r7o by Molmil
Structure of methyltransferase domain of Spb1 boudn to SAM
分子名称: AdoMet-dependent rRNA methyltransferase SPB1, S-ADENOSYLMETHIONINE
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-25
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Post-catalytic rRNA binding by the DEAD-box ATPase Spb4 and methyltransferase Spb1 guide the late nucleolar assembly of 60S ribosomes
To Be Published
6WMD
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BU of 6wmd by Molmil
Human Sun2-KASH4 complex
分子名称: MAGNESIUM ION, Nesprin-4, SUN domain-containing protein 2
著者Cruz, V.E, Schwartz, T.U.
登録日2020-04-21
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
J.Mol.Biol., 432, 2020
7UQB
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BU of 7uqb by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-04-19
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
7UOO
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BU of 7uoo by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-04-13
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
7UQZ
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BU of 7uqz by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1 D52A strain
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-04-20
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
7V08
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BU of 7v08 by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1 D52A suppressor 3 strain
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-05-10
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.36 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
7UUI
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BU of 7uui by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing post-rotation state from a SPB1 D52A strain
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleolar GTP-binding protein 2, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-04-28
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023

 

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