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PDB: 42 件

4YYH
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Crystal structure of BRD9 Bromodomain bound to a crotonyllysine peptide
分子名称: Bromodomain-containing protein 9, Histone H4
著者Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
登録日2015-03-23
公開日2015-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
4YYK
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BU of 4yyk by Molmil
Crystal structure of BRD9 Bromodomain bound to a crotonyllysine peptide
分子名称: Bromodomain-containing protein 9, Histone H4
著者Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
登録日2015-03-24
公開日2015-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
4YYM
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BU of 4yym by Molmil
Crystal structure of TAF1 BD2 Bromodomain bound to a butyryllysine peptide
分子名称: CALCIUM ION, Histone H4, Transcription initiation factor TFIID subunit 1
著者Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
登録日2015-03-24
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
4YYG
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BU of 4yyg by Molmil
Crystal structure of BRD9 Bromodomain bound to a butyryllysine peptide
分子名称: Bromodomain-containing protein 9, Histone H4
著者Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
登録日2015-03-23
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
4YYJ
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BU of 4yyj by Molmil
Crystal structure of BRD9 Bromodomain bound to a butyryllysine peptide
分子名称: Bromodomain-containing protein 9, Histone H4
著者Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
登録日2015-03-23
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
4YYI
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BU of 4yyi by Molmil
Crystal structure of BRD9 Bromodomain bound to an acetylated peptide
分子名称: Bromodomain-containing protein 9, Histone H4
著者Tang, Y, Bellon, S, Cochran, A.G, Poy, F.
登録日2015-03-23
公開日2015-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
1KAT
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BU of 1kat by Molmil
Solution Structure of a Phage-Derived Peptide Antagonist in Complex with Vascular Endothelial Growth Factor
分子名称: Phage-Derived Peptide Antagonist, Vascular Endothelial Growth Factor
著者Pan, B, Li, B, Russell, S.J, Tom, J.Y.K, Cochran, A.G, Fairbrother, W.J.
登録日2001-11-02
公開日2002-11-02
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution Structure of a Phage-derived Peptide Antagonist in Complex with Vascular Endothelial Growth Factor
J.Mol.Biol., 316, 2002
1KVG
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BU of 1kvg by Molmil
EPO-3 beta Hairpin Peptide
分子名称: Protein: EPO-3 Receptor Agonist
著者Skelton, N.J, Russell, S, de Sauvage, F, Cochran, A.G.
登録日2002-01-25
公開日2002-03-06
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Amino Acid Determinants of beta-Hairpin Conformation in Erythropoeitin Receptor Agonist Peptides Derived from a Phage Display Library
J.Mol.Biol., 316, 2002
1KVF
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BU of 1kvf by Molmil
EMP-18 Erythropoietin Receptor Agonist Peptide
分子名称: PROTEIN: EMP-18 Receptor Agonist
著者Skelton, N.J, Russell, S, de Sauvage, F, Cochran, A.G.
登録日2002-01-25
公開日2002-03-06
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Amino acid determinants of beta-hairpin conformation in erythropoeitin receptor agonist peptides derived from a phage display library
J.Mol.Biol., 316, 2002
1N0D
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BU of 1n0d by Molmil
Stability of cyclic beta-hairpins: Asymmetric contibutions from side chains of hydrogen bonded cross-strand residue pair
分子名称: bhp_VWLH, disulfide cyclized beta-hairpin peptide
著者Russell, S.J, Blandl, T, Skelton, N.J, Cochran, A.G.
登録日2002-10-11
公開日2003-02-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Stability of Cyclic Beta-Hairpins: Asymmetric Contributions From Side Chains of Hydrogen Bonded Cross-Strand Residue Pair
J.Am.Chem.Soc., 125, 2003
1N0A
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BU of 1n0a by Molmil
Turn stability in beta-hairpin peptides: 3:5 type I G1 bulge turns
分子名称: bhpw_pdg, beta-hairpin peptide
著者Blandl, T, Cochran, A.G, Skelton, N.J.
登録日2002-10-11
公開日2003-10-21
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Turn stability in beta-hairpin peptides: Investigation of peptides containing 3:5 type I G1 bulge turns
PROTEIN SCI., 12, 2003
1N0C
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BU of 1n0c by Molmil
Stability of cyclic beta-hairpins: Asymmetric contibutions from side chains of hydrogen bonded cross-strand residue pair
分子名称: bhp_HWLV, disulfide cyclized beta-hairpin peptide
著者Russel, S.J, Blandl, T, Skelton, N.J, Cochran, A.G.
登録日2002-10-11
公開日2003-10-21
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Stability of cyclic beta-hairpins: asymmetric contributions from side chains of a hydrogen-bonded cross-strand residue pair
J.AM.CHEM.SOC., 125, 2003
3COH
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BU of 3coh by Molmil
Crystal structure of Aurora-A in complex with a pentacyclic inhibitor
分子名称: 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1H)-one, Serine/threonine-protein kinase 6
著者Wiesmann, C, Raswson, T.E, Cochran, A.G.
登録日2008-03-28
公開日2009-02-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability.
J.Med.Chem., 51, 2008
3H0Z
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BU of 3h0z by Molmil
Aurora A in complex with a bisanilinopyrimidine
分子名称: 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-N-(2-chlorophenyl)benzamide, Serine/threonine-protein kinase 6
著者Wiesmann, C, Ultsch, M.H, Cochran, A.G.
登録日2009-04-10
公開日2009-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
J.Med.Chem., 52, 2009
3H10
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Aurora A inhibitor complex
分子名称: 9-chloro-7-(2,6-difluorophenyl)-N-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5H-pyrimido[5,4-d][2]benzazepin-2-amine, Serine/threonine-protein kinase 6
著者Wiesmann, C, Ultsch, M.H, Cochran, A.G.
登録日2009-04-10
公開日2009-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
J.Med.Chem., 52, 2009
1IN2
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BU of 1in2 by Molmil
Peptide Antagonist of IGFBP1, (i,i+7) Covalently Restrained Analog
分子名称: IGFBP-1 antagonist, PENTANE
著者Skelton, N.J, Chen, Y.M, Dubree, N, Quan, C, Jackson, D.Y, Cochran, A.G, Zobel, K, Deshayes, K, Baca, M, Pisabarro, M.T, Lowman, H.B.
登録日2001-05-11
公開日2001-05-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1IN3
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BU of 1in3 by Molmil
Peptide Antagonist of IGFBP1, (i,i+8) Covalently Restrained Analog
分子名称: IGFBP-1 antagonist, PENTANE
著者Skelton, N.J, Chen, Y.M, Dubree, N, Quan, C, Jackson, D.Y, Cochran, A.G, Zobel, K, Deshayes, K, Baca, M, Pisabarro, M.T, Lowman, H.B.
登録日2001-05-11
公開日2001-05-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
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