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PDB: 29 件

7TYM
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BU of 7tym by Molmil
Cryo-EM Structure of insulin receptor-related receptor (IRR) in active-state captured at pH 9. The 3D refinement was applied with C2 symmetry
分子名称: Insulin receptor-related protein
著者Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C.
登録日2022-02-13
公開日2023-02-15
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor.
Nat.Struct.Mol.Biol., 30, 2023
7TYJ
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BU of 7tyj by Molmil
Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was focused on one of two halves with C1 symmetry applied
分子名称: Insulin receptor-related protein
著者Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C.
登録日2022-02-13
公開日2023-02-15
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor.
Nat.Struct.Mol.Biol., 30, 2023
7TYK
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BU of 7tyk by Molmil
Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was applied with C2 symmetry
分子名称: Insulin receptor-related protein
著者Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C.
登録日2022-02-13
公開日2023-02-15
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor.
Nat.Struct.Mol.Biol., 30, 2023
6BNT
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BU of 6bnt by Molmil
Crystal structure of AP2 mu1 adaptin C-terminal domain with IRS-1 peptide
分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1
著者Kikuchi, S, Choi, E, Yu, H.
登録日2017-11-17
公開日2018-11-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling.
Nat Commun, 10, 2019
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件を2024-05-29に公開中

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