3HX9
| Structure of heme-degrader, MhuD (Rv3592), from Mycobacterium tuberculosis with two hemes bound in its active site | 分子名称: | CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Protein Rv3592 | 著者 | Chim, N, Nguyen, T.Q, Iniguez, A, Goulding, C.W. | 登録日 | 2009-06-19 | 公開日 | 2009-12-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Unusual Diheme Conformation of the Heme-Degrading Protein from Mycobacterium tuberculosis J.Mol.Biol., 395, 2009
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3IOS
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6DSV
| Bst DNA polymerase I post-chemistry (n+2) structure | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | 登録日 | 2018-06-14 | 公開日 | 2018-10-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6DSW
| Bst DNA polymerase I pre-chemistry (n) structure | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*G)-3'), DNA (5'-D(P*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | 登録日 | 2018-06-14 | 公開日 | 2018-10-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.589 Å) | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6DSY
| Bst DNA polymerase I post-chemistry (n+1) structure | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | 登録日 | 2018-06-14 | 公開日 | 2018-10-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6DSX
| Bst DNA polymerase I post-chemistry (n+1 with dATP soak) structure | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | 登録日 | 2018-06-14 | 公開日 | 2018-10-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6DSU
| Bst DNA polymerase I pre-insertion complex structure | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | 登録日 | 2018-06-14 | 公開日 | 2018-10-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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5VU5
| TNA polymerase, apo | 分子名称: | DNA polymerase | 著者 | Chim, N, Chaput, J.C. | 登録日 | 2017-05-18 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU7
| TNA polymerase, open ternary complex | 分子名称: | 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ... | 著者 | Chim, N, Chaput, J.C. | 登録日 | 2017-05-18 | 公開日 | 2017-12-06 | 最終更新日 | 2017-12-13 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU9
| TNA polymerase, translocated product | 分子名称: | DNA polymerase, DNA template, DNA/TNA hybrid primer | 著者 | Chim, N, Chaput, J.C. | 登録日 | 2017-05-18 | 公開日 | 2017-12-06 | 最終更新日 | 2017-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU8
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5VU6
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1PGY
| Solution structure of the UBA domain in Saccharomyces cerevisiae protein, Swa2p | 分子名称: | Swa2p | 著者 | Chim, N, Gall, W.E, Xiao, J, Harris, M.P, Graham, T.R, Krezel, A.M. | 登録日 | 2003-05-28 | 公開日 | 2004-03-23 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the ubiquitin-binding domain in Swa2p from Saccharomyces cerevisiae. PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
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7K5U
| Bst DNA polymerase I time-resolved structure, 48 hr post dATP and dCTP addition | 分子名称: | DNA (5'-D(P*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), DNA polymerase I, ... | 著者 | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | 登録日 | 2020-09-17 | 公開日 | 2021-03-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5P
| Bst DNA polymerase I time-resolved structure, 4 min post dATP addition | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | 著者 | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | 登録日 | 2020-09-17 | 公開日 | 2021-03-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5S
| Bst DNA polymerase I time-resolved structure, 4 hr post dATP and dCTP addition | 分子名称: | DNA (5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), DNA polymerase I, ... | 著者 | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | 登録日 | 2020-09-17 | 公開日 | 2021-03-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5O
| Bst DNA polymerase I time-resolved structure, 1 min post dATP addition | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | 著者 | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | 登録日 | 2020-09-17 | 公開日 | 2021-03-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5R
| Bst DNA polymerase I time-resolved structure, 120 min post dATP addition | 分子名称: | DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | 著者 | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | 登録日 | 2020-09-17 | 公開日 | 2021-03-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5Q
| Bst DNA polymerase I time-resolved structure, 8 min post dATP addition | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(P*G*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | 著者 | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | 登録日 | 2020-09-17 | 公開日 | 2021-03-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5T
| Bst DNA polymerase I time-resolved structure, 25.5 hr post dATP and dCTP addition | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), ... | 著者 | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | 登録日 | 2020-09-17 | 公開日 | 2021-03-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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4Y0L
| Mycobacterial membrane protein MmpL11D2 | 分子名称: | IODIDE ION, Putative membrane protein mmpL11, SULFATE ION | 著者 | Torres, R, Chim, N, Goulding, C.W. | 登録日 | 2015-02-06 | 公開日 | 2015-08-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Structure and Interactions of Periplasmic Domains of Crucial MmpL Membrane Proteins from Mycobacterium tuberculosis. Chem.Biol., 22, 2015
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6MU4
| Bst DNA polymerase I FANA/DNA binary complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA polymerase I, ... | 著者 | Jackson, L.N, Chim, N, Chaput, J.C. | 登録日 | 2018-10-22 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase. Nucleic Acids Res., 47, 2019
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6MU5
| Bst DNA polymerase I TNA/DNA binary complex | 分子名称: | DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA polymerase I, SULFATE ION, ... | 著者 | Jackson, L.N, Chim, N, Chaput, J.C. | 登録日 | 2018-10-22 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.912 Å) | 主引用文献 | Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase. Nucleic Acids Res., 47, 2019
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7RSU
| TNA polymerase, n+2 product | 分子名称: | DNA polymerase, Primer, Template | 著者 | Maola, V, Chaput, J, Chim, N. | 登録日 | 2021-08-11 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities. J.Am.Chem.Soc., 143, 2021
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7RSR
| Kod-RI incorporating PMT, n+2 | 分子名称: | DNA polymerase, Primer, Template | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | 登録日 | 2021-08-11 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
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