5W1X
 
 | | Crystal Structure of Humanpapillomavirus18 (HPV18) Capsid L1 Pentamers Bound to Heparin Oligosaccharides | | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, ... | | Authors: | Chen, X.S, Dasgupta, J. | | Deposit date: | 2017-06-05 | | Release date: | 2018-12-12 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.374 Å) | | Cite: | Structural basis of oligosaccharide receptor recognition by human papillomavirus.
J. Biol. Chem., 286, 2011
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2I0L
 | | X-ray crystal structure of Sap97 PDZ2 bound to the C-terminal peptide of HPV18 E6. | | Descriptor: | Disks large homolog 1, peptide E6 | | Authors: | Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M. | | Deposit date: | 2006-08-10 | | Release date: | 2007-02-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
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2I04
 | | X-ray crystal structure of MAGI-1 PDZ1 bound to the C-terminal peptide of HPV18 E6 | | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, SULFATE ION, ... | | Authors: | Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M. | | Deposit date: | 2006-08-09 | | Release date: | 2007-02-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
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2I0I
 | | X-ray crystal structure of Sap97 PDZ3 bound to the C-terminal peptide of HPV18 E6 | | Descriptor: | Disks large homolog 1, peptide E6 | | Authors: | Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M. | | Deposit date: | 2006-08-10 | | Release date: | 2007-02-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
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2H6O
 | | Epstein Barr Virus Major Envelope Glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Major outer envelope glycoprotein gp350, ... | | Authors: | Chen, X.S. | | Deposit date: | 2006-05-31 | | Release date: | 2006-10-31 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of the Epstein-Barr virus major envelope glycoprotein
Nat.Struct.Mol.Biol., 13, 2006
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1N25
 | | Crystal structure of the SV40 Large T antigen helicase domain | | Descriptor: | Large T Antigen, ZINC ION | | Authors: | Li, D, Zhao, R, Lilyestrom, W, Gai, D, Zhang, R, DeCaprio, J.A, Fanning, E, Jochimiak, A, Szakonyi, G, Chen, X.S. | | Deposit date: | 2002-10-21 | | Release date: | 2003-06-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen
Nature, 423, 2003
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6X91
 | | Crystal structure of MBP-fused human APOBEC1 | | Descriptor: | CACODYLATE ION, Maltodextrin-binding protein, C->U-editing enzyme APOBEC-1 chimera, ... | | Authors: | Wolfe, A.D, Li, S.-X, Chen, X.S. | | Deposit date: | 2020-06-02 | | Release date: | 2020-12-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.51 Å) | | Cite: | The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity.
NAR Cancer, 2, 2020
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2R5K
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2R5H
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2R5J
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2R5I
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1LTL
 | | THE DODECAMER STRUCTURE OF MCM FROM ARCHAEAL M. THERMOAUTOTROPHICUM | | Descriptor: | DNA replication initiator (Cdc21/Cdc54), ZINC ION | | Authors: | Fletcher, R.J, Bishop, B.E, Leon, R.P, Sclafani, R.A, Ogata, C.M, Chen, X.S. | | Deposit date: | 2002-05-20 | | Release date: | 2003-05-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Structure and function of MCM from archaeal M. Thermoautotrophicum
Nat.Struct.Biol., 10, 2003
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1GHQ
 | | CR2-C3D COMPLEX STRUCTURE | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, COMPLEMENT C3, CR2/CD121/C3D/EPSTEIN-BARR VIRUS RECEPTOR, ... | | Authors: | Szakonyi, G, Guthridge, J.M, Li, D, Holers, V.M, Chen, X.S. | | Deposit date: | 2001-01-11 | | Release date: | 2001-06-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structure of complement receptor 2 in complex with its C3d ligand.
Science, 292, 2001
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6LKA
 | | Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds | | Descriptor: | 3C proteinase, ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide | | Authors: | Li, P, Wu, S.Q, Xiao, T.Y.C, Li, Y.L, Su, Z.M, Hao, F, Hu, G.P, Hu, J, Lin, F.S, Chen, X.S, Gu, Z.X, He, H.Y, Li, J, Chen, S.H. | | Deposit date: | 2019-12-18 | | Release date: | 2020-06-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.033 Å) | | Cite: | Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent.
Bioorg.Med.Chem., 28, 2020
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4ME3
 | | 1.8 Angstrom Crystal Structure of the N-terminal Domain of an Archaeal MCM | | Descriptor: | DNA replication licensing factor MCM related protein, ZINC ION | | Authors: | Fu, Y, Slaymaker, I.M, Wang, G, Chen, X.S. | | Deposit date: | 2013-08-24 | | Release date: | 2014-01-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.794 Å) | | Cite: | The 1.8- angstrom Crystal Structure of the N-Terminal Domain of an Archaeal MCM as a Right-Handed Filament.
J.Mol.Biol., 426, 2014
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1SVO
 | | Structure of SV40 large T antigen helicase domain | | Descriptor: | ZINC ION, large T antigen | | Authors: | Gai, D, Zhao, R, Finkielstein, C.V, Chen, X.S. | | Deposit date: | 2004-03-29 | | Release date: | 2004-10-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen.
Cell(Cambridge,Mass.), 119, 2004
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1SVL
 | | Co-crystal structure of SV40 large T antigen helicase domain and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | | Authors: | Gai, D, Zhao, R, Finkielstein, C.V, Chen, X.S. | | Deposit date: | 2004-03-29 | | Release date: | 2004-10-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen.
Cell(Cambridge,Mass.), 119, 2004
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1SVM
 | | Co-crystal structure of SV40 large T antigen helicase domain and ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | | Authors: | Gai, D, Zhao, R, Finkielstein, C.V, Chen, X.S. | | Deposit date: | 2004-03-29 | | Release date: | 2004-10-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen.
Cell(Cambridge,Mass.), 119, 2004
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8UD4
 | | SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 1 | | Descriptor: | Non-structural protein 15, RNA (35-MER) | | Authors: | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | | Deposit date: | 2023-09-28 | | Release date: | 2024-04-24 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 15, 2024
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8UD5
 | | SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 2 | | Descriptor: | Non-structural protein 15, RNA (35-MER) | | Authors: | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | | Deposit date: | 2023-09-28 | | Release date: | 2024-04-24 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 15, 2024
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9ASK
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8UD2
 | | SARS-CoV-2 Nsp15, apo-form | | Descriptor: | Non-structural protein 15 | | Authors: | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | | Deposit date: | 2023-09-28 | | Release date: | 2024-04-24 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.33 Å) | | Cite: | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 15, 2024
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9ASJ
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9ASL
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8W0A
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