2P09
 
 | | Structural Insights into the Evolution of a Non-Biological Protein | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... | | 著者 | Smith, M, Rosenow, M, Wang, M, Allen, J.P, Szostak, J.W, Chaput, J.C. | | 登録日 | 2007-02-28 | | 公開日 | 2007-06-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization.
PLoS ONE, 2, 2007
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2P05
 | | Structural Insights into the Evolution of a Non-Biological Protein | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... | | 著者 | Smith, M, Rosenow, M, Wang, M, Allen, J.P, Szostak, J.W, Chaput, J.C. | | 登録日 | 2007-02-28 | | 公開日 | 2007-06-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization.
PLoS ONE, 2, 2007
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7TQW
 | | Kod RSGA incorporating PMT, n+2 | | 分子名称: | DNA polymerase, Primer, Template | | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | | 登録日 | 2022-01-27 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid.
Nucleic Acids Res., 50, 2022
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7RSU
 | | TNA polymerase, n+2 product | | 分子名称: | DNA polymerase, Primer, Template | | 著者 | Maola, V, Chaput, J, Chim, N. | | 登録日 | 2021-08-11 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities.
J.Am.Chem.Soc., 143, 2021
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8T3X
 | | TNA polymerase, closed ternary | | 分子名称: | 10-92, TNA polymerase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Maola, V, Chaput, J, Chim, N. | | 登録日 | 2023-06-07 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Directed Evolution of a Highly Efficient TNA Polymerase Achieved by Homologous Recombination
To Be Published
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6MU4
 | | Bst DNA polymerase I FANA/DNA binary complex | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA polymerase I, ... | | 著者 | Jackson, L.N, Chim, N, Chaput, J.C. | | 登録日 | 2018-10-22 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase.
Nucleic Acids Res., 47, 2019
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6MU5
 | | Bst DNA polymerase I TNA/DNA binary complex | | 分子名称: | DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA polymerase I, SULFATE ION, ... | | 著者 | Jackson, L.N, Chim, N, Chaput, J.C. | | 登録日 | 2018-10-22 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.912 Å) | | 主引用文献 | Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase.
Nucleic Acids Res., 47, 2019
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2P0X
 | | solution structure of a non-biological ATP-binding protein | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ZINC ION, abiotic ATP-binding, ... | | 著者 | Mansy, S.S, Szostak, J.W, Chaput, J.C. | | 登録日 | 2007-03-01 | | 公開日 | 2007-08-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Evolutionary Analysis of a Non-biological ATP-binding Protein
J.Mol.Biol., 371, 2007
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7RSR
 | | Kod-RI incorporating PMT, n+2 | | 分子名称: | DNA polymerase, Primer, Template | | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | | 登録日 | 2021-08-11 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid.
Nucleic Acids Res., 50, 2022
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2LUJ
 | | Solution structure of a parallel-stranded oligoisoguanine DNA pentaplex formed by d(T(iG)4T) in the presence of Cs ions | | 分子名称: | DNA (5'-D(*TP*(IGU)P*(IGU)P*(IGU)P*(IGU)P*T)-3') | | 著者 | Kang, M, Heuberger, B, Chaput, J.C, Switzer, C, Feigon, J. | | 登録日 | 2012-06-14 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of a Parallel-Stranded Oligoisoguanine DNA Pentaplex Formed by d(T(iG)4T) in the Presence of Cs(+) Ions.
Angew.Chem.Int.Ed.Engl., 51, 2012
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7RSS
 | | Kod-RI incorporating DNA, n+2 | | 分子名称: | DNA polymerase, Primer, Template | | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | | 登録日 | 2021-08-11 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid.
Nucleic Acids Res., 50, 2022
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3DGO
 | | A non-biological ATP binding protein with a Tyr-Phe mutation in the ligand binding domain | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP Binding Protein-DX, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Allen, J.P, Chaput, J.C. | | 登録日 | 2008-06-13 | | 公開日 | 2009-06-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A synthetic protein selected for ligand binding affinity mediates ATP hydrolysis.
Acs Chem.Biol., 4, 2009
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3DGM
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3DGN
 | | A non-biological ATP binding protein crystallized in the presence of 100 mM ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP Binding Protein-DX, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Simmons, C.R, Allen, J.P, Chaput, J.C. | | 登録日 | 2008-06-13 | | 公開日 | 2009-06-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A synthetic protein selected for ligand binding affinity mediates ATP hydrolysis.
Acs Chem.Biol., 4, 2009
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3DGL
 | | 1.8 A Crystal Structure of a Non-biological Protein with Bound ATP in a Novel Bent Conformation | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP Binding Protein-DX, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Simmons, C.R, Allen, J.P, Chaput, J.C. | | 登録日 | 2008-06-13 | | 公開日 | 2009-06-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A synthetic protein selected for ligand binding affinity mediates ATP hydrolysis.
Acs Chem.Biol., 4, 2009
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6DSW
 | | Bst DNA polymerase I pre-chemistry (n) structure | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*G)-3'), DNA (5'-D(P*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | | 登録日 | 2018-06-14 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.589 Å) | | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife, 7, 2018
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6DSU
 | | Bst DNA polymerase I pre-insertion complex structure | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | | 登録日 | 2018-06-14 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife, 7, 2018
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6DSX
 | | Bst DNA polymerase I post-chemistry (n+1 with dATP soak) structure | | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | | 登録日 | 2018-06-14 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife, 7, 2018
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3LTB
 | | X-ray structure of a non-biological ATP binding protein determined in the presence of 10 mM ATP at 2.6 A after 3 weeks of incubation | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP BINDING PROTEIN-DX, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C. | | 登録日 | 2010-02-15 | | 公開日 | 2010-09-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
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3LT8
 | | A non-biological ATP binding protein with a single point mutation (D65V), that contributes to optimized folding and ligand binding, crystallized in the presence of 100 mM ATP. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP BINDING PROTEIN-D65V, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C. | | 登録日 | 2010-02-15 | | 公開日 | 2010-09-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
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3LT9
 | | A non-biological ATP binding protein with a single point mutation (D65V), that contributes to optimized folding and ligand binding | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP BINDING PROTEIN-D65V, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C. | | 登録日 | 2010-02-15 | | 公開日 | 2010-09-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
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3LTD
 | | X-ray structure of a non-biological ATP binding protein determined at 2.8 A by multi-wavelength anomalous dispersion | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP BINDING PROTEIN-DX, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C. | | 登録日 | 2010-02-15 | | 公開日 | 2010-09-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
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3LTC
 | | X-ray structure of a non-biological ATP binding protein determined in the presence of 10 mM ATP at 2.0 A by multi-wavelength anomalous dispersion | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP BINDING PROTEIN-DX, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C. | | 登録日 | 2010-02-15 | | 公開日 | 2010-09-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
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3LTA
 | | Crystal structure of a non-biological ATP binding protein with a TYR-PHE mutation within the ligand binding domain | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP BINDING PROTEIN-DX, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C. | | 登録日 | 2010-02-15 | | 公開日 | 2010-09-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
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6DSV
 | | Bst DNA polymerase I post-chemistry (n+2) structure | | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | | 登録日 | 2018-06-14 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife, 7, 2018
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