5XO9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xo9 by Molmil](/molmil-images/mine/5xo9) | |
5XOL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xol by Molmil](/molmil-images/mine/5xol) | |
7SN7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sn7 by Molmil](/molmil-images/mine/7sn7) | |
6LUF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6luf by Molmil](/molmil-images/mine/6luf) | |
6LUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lua by Molmil](/molmil-images/mine/6lua) | |
3CYM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cym by Molmil](/molmil-images/mine/3cym) | Crystal structure of protein BAD_0989 from Bifidobacterium adolescentis | Descriptor: | GLYCEROL, SODIUM ION, Uncharacterized protein BAD_0989 | Authors: | Patskovsky, Y, Ozyurt, S, Freeman, J, Chang, S, Bain, K, Wasserman, S.R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-04-25 | Release date: | 2008-05-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of protein BAD_0989 from Bifidobacterium adolescentis. To be Published
|
|
5DBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dbk by Molmil](/molmil-images/mine/5dbk) | |
3CLW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3clw by Molmil](/molmil-images/mine/3clw) | Crystal structure of conserved exported protein from Bacteroides fragilis | Descriptor: | Conserved exported protein | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Chang, S, Ozyurt, K, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-03-20 | Release date: | 2008-04-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Crystal structure of conserved exported protein from Bacteroides fragilis. To be Published
|
|
6NRE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nre by Molmil](/molmil-images/mine/6nre) | Monomeric Lipocalin Can F 6 | Descriptor: | Lipocalin-Can f 6 allergen | Authors: | Clayton G, M, Kappler J, W, Chan, S. | Deposit date: | 2019-01-23 | Release date: | 2019-09-25 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural characteristics of lipocalin allergens: Crystal structure of the immunogenic dog allergen Can f 6. Plos One, 14, 2019
|
|
3D19
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d19 by Molmil](/molmil-images/mine/3d19) | Crystal structure of a conserved metalloprotein from Bacillus cereus | Descriptor: | Conserved metalloprotein, FE (III) ION, MAGNESIUM ION | Authors: | Bonanno, J.B, Patskovsky, Y, Freeman, J, Bain, K.T, Chang, S, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-05-05 | Release date: | 2008-07-08 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a conserved metalloprotein from Bacillus cereus. To be Published
|
|
5XO3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xo3 by Molmil](/molmil-images/mine/5xo3) | |
7TVI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tvi by Molmil](/molmil-images/mine/7tvi) | Alpha1/BetaB Heteromeric Glycine Receptor in Glycine-Bound State | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, Glycine receptor beta subunit 2, ... | Authors: | Gibbs, E, Chakrapani, S, Kumar, A. | Deposit date: | 2022-02-04 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Conformational transitions and allosteric modulation in a heteromeric glycine receptor Nat Commun, 14, 2023
|
|
7TU9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tu9 by Molmil](/molmil-images/mine/7tu9) | Alpha1/BetaB Heteromeric Glycine Receptor in Strychnine-Bound State | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor beta subunit 2, ... | Authors: | Gibbs, E, Kumar, A, Chakrapani, S. | Deposit date: | 2022-02-02 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Conformational transitions and allosteric modulation in a heteromeric glycine receptor Nat Commun, 14, 2023
|
|
3ED4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ed4 by Molmil](/molmil-images/mine/3ed4) | Crystal structure of putative arylsulfatase from escherichia coli | Descriptor: | ARYLSULFATASE, GLYCEROL, SODIUM ION, ... | Authors: | Patskovsky, Y, Ozyurt, S, Gilmore, M, Chang, S, Bain, K, Wasserman, S, Koss, J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-09-02 | Release date: | 2008-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Arylsulfatase from Escherichia Coli To be Published
|
|
7SQJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sqj by Molmil](/molmil-images/mine/7sqj) | |
5WYR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wyr by Molmil](/molmil-images/mine/5wyr) | Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa | Descriptor: | SINEFUNGIN, tRNA (guanine-N(1)-)-methyltransferase | Authors: | Jaroensuk, J, Liew, C.W, Atichartpongkul, S, Chionh, Y.H, Wong, Y.H, Zhong, W.H, McBee, M.E, Thongdee, N, Prestwich, E.G, DeMott, M.S, Mongkolsuk, S, Dedon, P.C, Lescar, J, Fuangthong, M. | Deposit date: | 2017-01-15 | Release date: | 2017-12-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD fromPseudomonas aeruginosa. Rna, 2019
|
|
6GQJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gqj by Molmil](/molmil-images/mine/6gqj) | Crystal structure of human c-KIT kinase domain in complex with AZD3229-analogue (compound 18) | Descriptor: | 2-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxy-phenyl]-~{N}-(1-propan-2-ylpyrazol-4-yl)ethanamide, Mast/stem cell growth factor receptor Kit | Authors: | Schimpl, M, Hardy, C.J, Ogg, D.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y. | Deposit date: | 2018-06-07 | Release date: | 2018-09-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors. J. Med. Chem., 61, 2018
|
|
3N3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3n3d by Molmil](/molmil-images/mine/3n3d) | Crystal structure of geranylgeranyl pyrophosphate synthase from lactobacillus brevis atcc 367 | Descriptor: | Geranylgeranyl pyrophosphate synthase, SULFATE ION | Authors: | Patskovsky, Y, Toro, R, Rutter, M, Chang, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York Structural GenomiX Research Consortium (NYSGXRC), New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-05-19 | Release date: | 2010-06-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Geranylgeranyl Pyrophosphate Synthase from Lactobacillus Brevis To be Published
|
|
3G12
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g12 by Molmil](/molmil-images/mine/3g12) | Crystal structure of a putative lactoylglutathione lyase from Bdellovibrio bacteriovorus | Descriptor: | Putative lactoylglutathione lyase, SULFATE ION | Authors: | Patskovsky, Y, Madegowda, M, Gilmore, M, Chang, S, Maletic, M, Smith, D, Sauder, J.M, Burley, S.K, Swaminathan, S, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-01-29 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Crystal structure of a putative lactoylglutathione lyase from Bdellovibrio bacteriovorus To be Published
|
|
5XOA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xoa by Molmil](/molmil-images/mine/5xoa) | |
5XO4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xo4 by Molmil](/molmil-images/mine/5xo4) | |
5N2M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n2m by Molmil](/molmil-images/mine/5n2m) | Crystal structure of the first bromodomain of human BRD4 in complex with a tetrahydroquinoline analogue | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, propan-2-yl ~{N}-[(2~{S},4~{R})-6-(3-acetamidophenyl)-1-ethanoyl-2-methyl-3,4-dihydro-2~{H}-quinolin-4-yl]carbamate | Authors: | Tallant, C, Slavish, P.J, Siejka, P, Bharatham, N, Shadrick, W.R, Chai, S, Young, B.M, Boyd, V.A, Heroven, C, Wiggers, H.J, Picaud, S, Fedorov, O, Krojer, T, Chen, T, Lee, R.E, Guy, R.K, Shelat, A.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2017-02-07 | Release date: | 2018-02-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Crystal structure of the first bromodomain of human BRD4 in complex with a tetrahydroquinoline analogue To Be Published
|
|
6GQO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gqo by Molmil](/molmil-images/mine/6gqo) | Crystal structure of human KDR (VEGFR2) kinase domain in complex with AZD3229-analogue (compound 18) | Descriptor: | 2-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxy-phenyl]-~{N}-(1-propan-2-ylpyrazol-4-yl)ethanamide, Vascular endothelial growth factor receptor 2 | Authors: | Ogg, D.J, Schimpl, M, Hardy, C.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y. | Deposit date: | 2018-06-07 | Release date: | 2018-09-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors. J. Med. Chem., 61, 2018
|
|
3FYF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fyf by Molmil](/molmil-images/mine/3fyf) | Crystal structure of uncharacterized protein bvu_3222 from bacteroides vulgatus | Descriptor: | PROTEIN BVU-3222 | Authors: | Patskovsky, Y, Bonanno, J.B, Ozyurt, S, Rutter, M, Chang, S, Groshong, C, Koss, J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-01-22 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Protein Bvu-3222 from Bacteroides Vulgatus To be Published
|
|
6GQK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gqk by Molmil](/molmil-images/mine/6gqk) | Crystal structure of human c-KIT kinase domain in complex with AZD3229-analogue (compound 23) | Descriptor: | Mast/stem cell growth factor receptor Kit, ~{N}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(1-ethylpyrazol-4-yl)ethanamide | Authors: | Schimpl, M, Hardy, C.J, Ogg, D.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y. | Deposit date: | 2018-06-07 | Release date: | 2018-09-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors. J. Med. Chem., 61, 2018
|
|