6BNN
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![BU of 6bnn by Molmil](/molmil-images/mine/6bnn) | Crystal structure of V278E-glyoxalase I mutant from Zea mays in space group P4(1)2(1)2 | 分子名称: | COBALT (II) ION, FORMIC ACID, GLUTATHIONE, ... | 著者 | Alvarez, C.E, Agostini, R.B, Gonzalez, J.M, Drincovich, M.F, Campos Bermudez, V.A, Klinke, S. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays. Febs J., 286, 2019
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6D3M
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![BU of 6d3m by Molmil](/molmil-images/mine/6d3m) | FT_T dioxygenase with bound quizalofop | 分子名称: | (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | 著者 | Rydel, T.J, Halls, C.E. | 登録日 | 2018-04-16 | 公開日 | 2018-08-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops. Pest Manag. Sci., 75, 2019
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1GKF
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![BU of 1gkf by Molmil](/molmil-images/mine/1gkf) | Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, PENICILLIN G ACYLASE ALPHA SUBUNIT, ... | 著者 | McVey, C.E, Walsh, M.A, Dodson, G.G, Wilson, K.S, Brannigan, J.A. | 登録日 | 2001-08-13 | 公開日 | 2002-01-04 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism J.Mol.Biol., 313, 2001
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6D3I
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![BU of 6d3i by Molmil](/molmil-images/mine/6d3i) | ftv7 dioxygenase with 2,4-D bound | 分子名称: | (2,4-DICHLOROPHENOXY)ACETIC ACID, 2-OXOGLUTARIC ACID, COBALT (II) ION, ... | 著者 | Rydel, T.J, Halls, C.E. | 登録日 | 2018-04-16 | 公開日 | 2018-08-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.196 Å) | 主引用文献 | Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops. Pest Manag. Sci., 75, 2019
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6CUV
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![BU of 6cuv by Molmil](/molmil-images/mine/6cuv) | Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6 | 分子名称: | PHOSPHATE ION, SODIUM ION, Tryptophan synthase beta chain 1 | 著者 | Scheele, R.A, Buller, A.R, Boville, C.E, Arnold, F.H. | 登録日 | 2018-03-26 | 公開日 | 2018-09-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Engineered Biosynthesis of beta-Alkyl Tryptophan Analogues. Angew. Chem. Int. Ed. Engl., 57, 2018
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6D3H
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![BU of 6d3h by Molmil](/molmil-images/mine/6d3h) | FT_T dioxygenase with bound dichlorprop | 分子名称: | (2R)-2-(2,4-dichlorophenoxy)propanoic acid, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | 著者 | Rydel, T.J, Halls, C.E. | 登録日 | 2018-04-16 | 公開日 | 2018-08-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops. Pest Manag. Sci., 75, 2019
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1GK9
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![BU of 1gk9 by Molmil](/molmil-images/mine/1gk9) | Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, PENICILLIN G ACYLASE ALPHA SUBUNIT, ... | 著者 | McVey, C.E, Walsh, M.A, Dodson, G.G, Wilson, K.S, Brannigan, J.A. | 登録日 | 2001-08-10 | 公開日 | 2002-01-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal Structures of Penicillin Acylase Enzyme-Substrate Complexes: Structural Insights Into the Catalytic Mechanism J.Mol.Biol., 313, 2001
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1GID
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![BU of 1gid by Molmil](/molmil-images/mine/1gid) | CRYSTAL STRUCTURE OF A GROUP I RIBOZYME DOMAIN: PRINCIPLES OF RNA PACKING | 分子名称: | COBALT HEXAMMINE(III), MAGNESIUM ION, P4-P6 RNA RIBOZYME DOMAIN | 著者 | Cate, J.H, Gooding, A.R, Podell, E, Zhou, K, Golden, B.L, Kundrot, C.E, Cech, T.R, Doudna, J.A. | 登録日 | 1996-08-22 | 公開日 | 1996-12-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a group I ribozyme domain: principles of RNA packing. Science, 273, 1996
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6BNX
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![BU of 6bnx by Molmil](/molmil-images/mine/6bnx) | Crystal structure of V278E-glyoxalase I mutant from Zea mays in space group P6(3) | 分子名称: | COBALT (II) ION, Lactoylglutathione lyase | 著者 | Alvarez, C.E, Agostini, R.B, Gonzalez, J.M, Drincovich, M.F, Campos Bermudez, V.A, Klinke, S. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays. Febs J., 286, 2019
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6BNZ
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![BU of 6bnz by Molmil](/molmil-images/mine/6bnz) | Crystal structure of E144Q-glyoxalase I mutant from Zea mays in space group P4(1)2(1)2 | 分子名称: | COBALT (II) ION, FORMIC ACID, GLUTATHIONE, ... | 著者 | Alvarez, C.E, Agostini, R.B, Gonzalez, J.M, Drincovich, M.F, Campos Bermudez, V.A, Klinke, S. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays. Febs J., 286, 2019
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6C42
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![BU of 6c42 by Molmil](/molmil-images/mine/6c42) | Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1156 | 分子名称: | (2R,3S,4R)-3-(4-hydroxyphenyl)-4-methyl-2-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-3,4-dihydro-2H-1-benzopyran-7-ol, Estrogen receptor | 著者 | Fanning, S.W, Hodges-Gallager, L, Myles, D.C, Sun, R, Fowler, C.E, Green, B.D, Harmon, C.L, Greene, G.L, Kushner, P.J. | 登録日 | 2018-01-11 | 公開日 | 2018-02-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity. Nat Commun, 9, 2018
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1H2G
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![BU of 1h2g by Molmil](/molmil-images/mine/1h2g) | Altered substrate specificity mutant of penicillin acylase | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, PENICILLIN G ACYLASE ALPHA SUBUNIT, ... | 著者 | McVey, C.E, Morillas, M, Brannigan, J.A, Ladurner, A.G, Forney, L.J, Virden, R. | 登録日 | 2002-08-08 | 公開日 | 2003-07-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mutations of Penicillin Acylase Residue B71 Extend Substrate Specificity by Decreasing Steric Constraints for Substrate Binding Biochem.J., 371, 2003
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1GRJ
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1H93
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![BU of 1h93 by Molmil](/molmil-images/mine/1h93) | ACTIVE MUTANT (S215->C) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES | 分子名称: | CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, GLYCEROL | 著者 | Adams, M.J, Naylor, C.E, Gover, S. | 登録日 | 2001-02-23 | 公開日 | 2001-05-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Nadp+ and Nad+ Binding to the Dual Coenzyme Specific Enzyme Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: Different Interdomain Hinge Angles are Seen in Different Binary and Ternary Complexes Acta Crystallogr.,Sect.D, 57, 2001
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1H9A
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![BU of 1h9a by Molmil](/molmil-images/mine/1h9a) | COMPLEX OF ACTIVE MUTANT (Q365->C) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM L. MESENTEROIDES WITH COENZYME NADP | 分子名称: | GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | 著者 | Adams, M.J, Naylor, C.E, Gover, S. | 登録日 | 2001-03-06 | 公開日 | 2001-05-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Nadp+ and Nad+ Binding to the Dual Coenzyme Specific Enzyme Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: Different Interdomain Hinge Angles are Seen in Different Binary and Ternary Complexes Acta Crystallogr.,Sect.D, 57, 2001
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1H94
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1H9B
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7Y8F
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![BU of 7y8f by Molmil](/molmil-images/mine/7y8f) | Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with an Inhibitor 30o and GRIP Peptide | 分子名称: | DI(HYDROXYETHYL)ETHER, Estrogen receptor, Grip peptide, ... | 著者 | Min, J, Hu, H.B, Yang, Y, Dong, C.E, Zhou, H.B, Chen, C.-C, Guo, R.-T. | 登録日 | 2022-06-23 | 公開日 | 2023-04-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structure-guided identification of novel dual-targeting estrogen receptor alpha degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer. Eur.J.Med.Chem., 253, 2023
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7Y8G
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![BU of 7y8g by Molmil](/molmil-images/mine/7y8g) | Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with an Inhibitor 30a and GRIP Peptide | 分子名称: | DI(HYDROXYETHYL)ETHER, Estrogen receptor, Grip peptide, ... | 著者 | Min, J, Hu, H.B, Yang, Y, Dong, C.E, Zhou, H.B, Chen, C.-C, Guo, R.-T. | 登録日 | 2022-06-23 | 公開日 | 2023-04-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structure-guided identification of novel dual-targeting estrogen receptor alpha degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer. Eur.J.Med.Chem., 253, 2023
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1T4D
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![BU of 1t4d by Molmil](/molmil-images/mine/1t4d) | Crystal structure of Escherichia coli aspartate beta-semialdehyde dehydrogenase (EcASADH), at 1.95 Angstrom resolution | 分子名称: | Aspartate-semialdehyde dehydrogenase | 著者 | Nichols, C.E, Dhaliwal, B, Lockyer, M, Hawkins, A.R, Stammers, D.K. | 登録日 | 2004-04-29 | 公開日 | 2004-08-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | High-resolution Structures Reveal Details of Domain Closure and "Half-of-sites-reactivity" in Escherichia coli Aspartate beta-Semialdehyde Dehydrogenase. J.Mol.Biol., 341, 2004
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1SZH
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![BU of 1szh by Molmil](/molmil-images/mine/1szh) | Crystal Structure of C. elegans HER-1 | 分子名称: | ACETATE ION, Her-1 protein | 著者 | Hamaoka, B.Y, Dann III, C.E, Geisbrecht, B.V, Leahy, D.J. | 登録日 | 2004-04-05 | 公開日 | 2004-08-10 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A. Proc.Natl.Acad.Sci.USA, 101, 2004
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1U94
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1U8A
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![BU of 1u8a by Molmil](/molmil-images/mine/1u8a) | Crystal Structure of Mycobacterium Tuberculosis Shikimate Kinase in Complex with Shikimate and ADP at 2.15 Angstrom Resolution | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | 著者 | Dhaliwal, B, Nichols, C.E, Ren, J, Lockyer, M, Charles, I, Hawkins, A.R, Stammers, D.K. | 登録日 | 2004-08-05 | 公開日 | 2004-10-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase. Febs Lett., 574, 2004
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1SFJ
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![BU of 1sfj by Molmil](/molmil-images/mine/1sfj) | 2.4A Crystal structure of Staphylococcus aureus type I 3-dehydroquinase, with 3-dehydroquinate bound | 分子名称: | 3-DEHYDROSHIKIMATE, 3-dehydroquinate dehydratase | 著者 | Nichols, C.E, Lockyer, M, Hawkins, A.R, Stammers, D.K. | 登録日 | 2004-02-19 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of Staphylococcus aureus type I dehydroquinase from enzyme turnover experiments Proteins, 56, 2004
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1S73
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![BU of 1s73 by Molmil](/molmil-images/mine/1s73) | Crystal Structure of Mesopone Cytochrome c Peroxidase (R-isomer) [MpCcP-R] | 分子名称: | Cytochrome c peroxidase, mitochondrial, FE-(4-MESOPORPHYRINONE)-R-ISOMER | 著者 | Bhaskar, B, Immoos, C.E, Sulc, F, Choen, M.S, Farmer, P.J, Poulos, T.L. | 登録日 | 2004-01-28 | 公開日 | 2005-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Crystal structures of reduced, resting and NO-bound states of mesopone cytochorme c peroxidase (MpCcP) (R-isomer) To be Published
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