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PDB: 36 件

2KNH
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The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide
分子名称: Protein CBFA2T1, Transcription factor 12
著者Park, S, Cierpicki, T, Tonelli, M, Bushweller, J.H.
登録日2009-08-25
公開日2009-10-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.
Blood, 113, 2009
2K73
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Solution NMR structure of integral membrane protein DsbB
分子名称: Disulfide bond formation protein B
著者Zhou, Y, Cierpicki, T, Flores Jimenez, R.H, Lukasik, S.M, Ellena, J.F, Cafiso, D.S, Kadokura, H, Beckwith, J, Bushweller, J.H.
登録日2008-08-01
公開日2008-10-07
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation.
Mol.Cell, 31, 2008
2KKF
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Solution structure of MLL CXXC domain in complex with palindromic CPG DNA
分子名称: 5'-D(*CP*CP*CP*TP*GP*CP*GP*CP*AP*GP*GP*G)-3', Histone-lysine N-methyltransferase HRX, ZINC ION
著者Cierpicki, T, Riesbeck, J.E, Grembecka, J.E, Lukasik, S.M, Popovic, R, Omonkowska, M, Shultis, D.S, Zeleznik-Le, N.J, Bushweller, J.H.
登録日2009-06-18
公開日2009-12-08
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia.
Nat.Struct.Mol.Biol., 17, 2010
2K74
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Solution NMR structure of DsbB-ubiquinone complex
分子名称: Disulfide bond formation protein B, UBIQUINONE-2
著者Zhou, Y, Cierpicki, T, Flores Jimenez, R.H, Lukasik, S.M, Ellena, J.F, Cafiso, D.S, Kadokura, H, Beckwith, J, Bushweller, J.H.
登録日2008-08-01
公開日2008-10-07
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation.
Mol.Cell, 31, 2008
2KYX
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Solution structure of the RRM domain of CYP33
分子名称: Peptidyl-prolyl cis-trans isomerase E
著者Park, S, Bushweller, J.H.
登録日2010-06-09
公開日2010-08-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression .
Biochemistry, 49, 2010
2KYU
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The solution structure of the PHD3 finger of MLL
分子名称: Histone-lysine N-methyltransferase MLL, ZINC ION
著者Park, S, Bushweller, J.H.
登録日2010-06-08
公開日2010-08-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression.
Biochemistry, 49, 2010
2LM0
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Solution structure of the AF4-AF9 complex
分子名称: AF4/FMR2 family member 1/Protein AF-9 chimera
著者Leach, B.I, Kuntimaddi, A, Schmidt, C.R, Cierpicki, T, Johnson, S.A, Bushweller, J.H.
登録日2011-11-18
公開日2013-01-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Leukemia Fusion Target AF9 Is an Intrinsically Disordered Transcriptional Regulator that Recruits Multiple Partners via Coupled Folding and Binding.
Structure, 21, 2013
2N4Q
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Solution NMR structure of CBX8 in complex with AF9 (CBX8-AF9)
分子名称: Chromobox protein homolog 8, Protein AF-9
著者Kuntimaddi, A, Leach, B.I, Bushweller, J.H.
登録日2015-06-30
公開日2016-07-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of CBX8 in complex with AF9 (CBX8-AF9)
To be Published
2MV7
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Solution NMR structure of DOT1L in complex with AF9 (DOT1L-AF9)
分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-9
著者Kuntimaddi, A, Bushweller, J.H.
登録日2014-09-24
公開日2015-04-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential.
Cell Rep, 11, 2015
2ODD
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Solution structure of the MYND domain from AML1-ETO complexed with SMRT, a corepressor
分子名称: Protein CBFA2T1, SMRT, ZINC ION
著者Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H.
登録日2006-12-22
公開日2007-06-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
2OD1
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Solution structure of the MYND domain from human AML1-ETO
分子名称: Protein CBFA2T1, ZINC ION
著者Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H.
登録日2006-12-21
公開日2007-06-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
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