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PDB: 16 件
3L4J
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BU of 3l4j by Molmil
Topoisomerase II-DNA cleavage complex, apo
分子名称: 3'-THIO-THYMIDINE-5'-PHOSPHATE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ...
著者Schmidt, B.H, Burgin, A.B, Deweese, J.E, Osheroff, N, Berger, J.M.
登録日2009-12-20
公開日2010-05-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases.
Nature, 465, 2010
3L4K
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Topoisomerase II-DNA cleavage complex, metal-bound
分子名称: 3'-THIO-THYMIDINE-5'-PHOSPHATE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ...
著者Schmidt, B.H, Burgin, A.B, Deweese, J.E, Osheroff, N, Berger, J.M.
登録日2009-12-20
公開日2010-05-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases.
Nature, 465, 2010
3UWB
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BU of 3uwb by Molmil
Crystal structure of a probable peptide deformylase from strucynechococcus phage S-SSM7 in complex with actinonin
分子名称: 1,2-ETHANEDIOL, ACTINONIN, CHLORIDE ION, ...
著者Lorimer, D, Abendroth, J, Edwards, T.E, Burgin, A, Segall, A, Rohwer, F.
登録日2011-12-01
公開日2013-01-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and function of a cyanophage-encoded peptide deformylase.
ISME J, 7, 2013
3UWA
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BU of 3uwa by Molmil
Crystal structure of a probable peptide deformylase from synechococcus phage S-SSM7
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, RIIA-RIIB membrane-associated protein, ZINC ION
著者Lorimer, D, Abendroth, J, Edwards, T.E, Burgin, A, Segall, A, Rohwer, F.
登録日2011-12-01
公開日2013-01-09
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and function of a cyanophage-encoded peptide deformylase.
ISME J, 7, 2013
1NH3
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BU of 1nh3 by Molmil
Human Topoisomerase I Ara-C Complex
分子名称: 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3', 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3', ...
著者Chrencik, J.E, Burgin, A.B, Pommier, Y, Stewart, L, Redinbo, M.R.
登録日2002-12-18
公開日2003-03-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex
J.Biol.Chem., 278, 2003
4DR9
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BU of 4dr9 by Molmil
Crystal structure of a peptide deformylase from synechococcus elongatus in complex with actinonin
分子名称: ACTINONIN, BROMIDE ION, Peptide deformylase, ...
著者Lorimer, D, Abendroth, J, Craig, T, Burgin, A, Segall, A, Rohwler, F.
登録日2012-02-17
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and function of a cyanophage-encoded peptide deformylase.
ISME J, 7, 2013
4DR8
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Crystal structure of a peptide deformylase from Synechococcus elongatus
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ...
著者Lorimer, D, Abendroth, J, Craig, T, Burgin, A, Segall, A, Rohwer, F.
登録日2012-02-17
公開日2013-03-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure and function of a cyanophage-encoded peptide deformylase.
ISME J, 7, 2013
2RHJ
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BU of 2rhj by Molmil
Synthetic Gene Encoded Bacillus Subtilis FtsZ with Two Sulfate Ions and Sodium Ion in the Nucleotide Pocket
分子名称: ACETATE ION, Cell Division Protein ftsZ, SODIUM ION, ...
著者Lovell, S, Halloran, Z, Hjerrild, K, Sheridan, D, Burgin, A, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
登録日2007-10-09
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.761 Å)
主引用文献Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
BMC Biotechnol., 9, 2009
2RHO
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Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP and GTP-gamma-S
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell Division Protein ftsZ, GUANOSINE-5'-DIPHOSPHATE
著者Lovell, S, Halloran, Z, Hjerrild, K, Sheridan, D, Burgin, A, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
登録日2007-10-09
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
BMC Biotechnol., 9, 2009
2RHL
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BU of 2rhl by Molmil
Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP
分子名称: Cell Division Protein ftsZ, GUANOSINE-5'-DIPHOSPHATE
著者Lovell, S, Halloran, Z, Hjerrild, K, Sheridan, D, Burgin, A, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
登録日2007-10-09
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
BMC Biotechnol., 9, 2009
2RHH
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BU of 2rhh by Molmil
Synthetic Gene Encoded Bacillus Subtilis FtsZ with Bound Sulfate Ion
分子名称: Cell Division Protein ftsZ, SULFATE ION
著者Lovell, S, Halloran, Z, Hjerrild, K, Sheridan, D, Burgin, A, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
登録日2007-10-09
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
BMC Biotechnol., 9, 2009
1RR8
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BU of 1rr8 by Molmil
Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I
分子名称: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC ACID, 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T*GP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', ...
著者Chrencik, J.E, Staker, B.L, Burgin, A.B, Stewart, L, Redinbo, M.R.
登録日2003-12-08
公開日2004-07-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mechanisms of camptothecin resistance by human topoisomerase I mutations
J.Mol.Biol., 339, 2004
1SEU
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BU of 1seu by Molmil
Human DNA Topoisomerase I (70 Kda) In Complex With The Indolocarbazole SA315F and Covalent Complex With A 22 Base Pair DNA Duplex
分子名称: 2,10-DIHYDROXY-12-(BETA-D-GLUCOPYRANOSYL)-6,7,12,13-TETRAHYDROINDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE-5,7-DIONE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ...
著者Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B.
登録日2004-02-18
公開日2005-04-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
J.Med.Chem., 48, 2005
1SC7
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Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex
分子名称: 4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ...
著者Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B.
登録日2004-02-11
公開日2005-04-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
J.Med.Chem., 48, 2005
1T8I
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BU of 1t8i by Molmil
Human DNA Topoisomerase I (70 Kda) In Complex With The Poison Camptothecin and Covalent Complex With A 22 Base Pair DNA Duplex
分子名称: 4-ETHYL-4-HYDROXY-1,12-DIHYDRO-4H-2-OXA-6,12A-DIAZA-DIBENZO[B,H]FLUORENE-3,13-DIONE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ...
著者Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B.
登録日2004-05-12
公開日2005-05-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
J.Med.Chem., 48, 2005
1RRJ
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BU of 1rrj by Molmil
Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I
分子名称: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC ACID, 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T*GP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', ...
著者Chrencik, J.E, Staker, B.L, Burgin, A.B, Stewart, L, Redinbo, M.R.
登録日2003-12-08
公開日2004-07-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanisms of camptothecin resistance by human topoisomerase I mutations
J.Mol.Biol., 339, 2004

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