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PDB: 32 件
7QSR
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CryoEM structure of the Ectodomain of Human PLA2R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Secretory phospholipase A2 receptor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Briggs, D.C, Lockhart-Cairns, M.P, Baldock, C.
登録日2022-01-14
公開日2022-07-20
最終更新日2022-08-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch.
Proc.Natl.Acad.Sci.USA, 119, 2022
6FPY
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Inter-alpha-inhibitor heavy chain 1, wild type
分子名称: GLYCEROL, Inter-alpha-trypsin inhibitor heavy chain H1, MAGNESIUM ION
著者Briggs, D.C, Day, A.J.
登録日2018-02-12
公開日2019-02-27
最終更新日2020-03-18
実験手法X-RAY DIFFRACTION (2.339 Å)
主引用文献Inter-alpha-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation
J.Biol.Chem., 2020
6FPZ
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Inter-alpha-inhibitor heavy chain 1, D298A
分子名称: ACETATE ION, GLYCEROL, Inter-alpha-trypsin inhibitor heavy chain H1
著者Briggs, D.C, Day, A.J.
登録日2018-02-12
公開日2019-02-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inter-alpha-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation
J.Biol.Chem., 2020
6FOA
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BU of 6foa by Molmil
Human Xylosyltransferase 1 apo structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, SODIUM ION, ...
著者Briggs, D.C, Hohenester, E.
登録日2018-02-06
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.869 Å)
主引用文献Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
6EJC
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Human Xylosyltransferase 1 in complex with peptide QEEEGSGVGQGG
分子名称: PHOSPHATE ION, Protein AMBP, SODIUM ION, ...
著者Briggs, D.C, Hohenester, E.
登録日2017-09-20
公開日2018-05-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.057 Å)
主引用文献Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
6EJE
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Human Xylosyltransferase 1 in complex with peptide PAAEGSGEQDFT
分子名称: PHOSPHATE ION, SODIUM ION, Syndecan-1, ...
著者Briggs, D.C, Hohenester, E.
登録日2017-09-20
公開日2018-05-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
6EJ8
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Human Xylosyltransferase 1 in complex with peptide QEEEGSGGGQGG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Protein AMBP, ...
著者Briggs, D.C, Hohenester, E.
登録日2017-09-20
公開日2018-05-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
6EJD
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Human Xylosyltransferase 1 in complex with peptide QEEEGSGGPQGG
分子名称: PHOSPHATE ION, Protein AMBP, Xylosyltransferase 1
著者Briggs, D.C, Hohenester, E.
登録日2017-09-20
公開日2018-05-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.684 Å)
主引用文献Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
6EJB
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Human Xylosyltransferase 1 in complex with peptide QEEEGSAGGQGG
分子名称: PHOSPHATE ION, Protein AMBP, Xylosyltransferase 1
著者Briggs, D.C, Hohenester, E.
登録日2017-09-20
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.557 Å)
主引用文献Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
6EJ7
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Human Xylosyltransferase 1 in complex with UDP-xylose and peptide QEEEGAGGGQGG
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Briggs, D.C, Hohenester, E.
登録日2017-09-20
公開日2018-05-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
6EJA
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Human Xylosyltransferase 1 in complex with peptide QEEEYSGGGQGG
分子名称: Protein AMBP, SODIUM ION, Xylosyltransferase 1
著者Briggs, D.C, Hohenester, E.
登録日2017-09-20
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
6EJ9
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BU of 6ej9 by Molmil
Human Xylosyltransferase 1 in complex with peptide QEPEGSGGGQGG
分子名称: PHOSPHATE ION, Protein AMBP, SODIUM ION, ...
著者Briggs, D.C, Hohenester, E.
登録日2017-09-20
公開日2018-05-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
7NZN
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BU of 7nzn by Molmil
Structure of RET kinase domain bound to inhibitor JB-48
分子名称: 2-[4-[[4-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-6-[(3-methyl-1~{H}-pyrazol-5-yl)amino]pyrimidin-2-yl]amino]phenyl]-~{N}-(3-fluorophenyl)ethanamide, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret
著者Briggs, D.C, McDonald, N.Q.
登録日2021-03-24
公開日2022-02-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.
J.Med.Chem., 65, 2022
5IK4
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BU of 5ik4 by Molmil
Laminin A2LG45 C-form, Apo.
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
5IK7
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BU of 5ik7 by Molmil
Laminin A2LG45 I-form, Apo.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
5IK5
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BU of 5ik5 by Molmil
Laminin A2LG45 C-form, G6/7 bound.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, CALCIUM ION, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
5IK8
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BU of 5ik8 by Molmil
Laminin A2LG45 I-form, G6/7 bound.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
2J17
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BU of 2j17 by Molmil
pTyr bound form of SDP-1
分子名称: MAGNESIUM ION, O-PHOSPHOTYROSINE, TYROSINE-PROTEIN PHOSPHATASE YIL113W
著者Briggs, D.C, McDonald, N.Q.
登録日2006-08-09
公開日2007-05-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases.
Nature, 447, 2007
2IYB
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BU of 2iyb by Molmil
Structure of complex between the 3rd LIM domain of TES and the EVH1 domain of Mena
分子名称: PROTEIN ENABLED HOMOLOG, TESTIN, ZINC ION
著者Briggs, D.C, McDonald, N.Q.
登録日2006-07-14
公開日2007-10-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding.
Mol. Cell, 28, 2007
2J16
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BU of 2j16 by Molmil
Apo & Sulphate bound forms of SDP-1
分子名称: MAGNESIUM ION, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE YIL113W
著者Briggs, D.C, McDonald, N.Q.
登録日2006-08-09
公開日2007-05-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases.
Nature, 447, 2007
1V1P
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BU of 1v1p by Molmil
The structure SSL from Staphylococcus Aureus from an orthorhombic crystal form
分子名称: Exotoxin 1
著者Briggs, D.C, Naylor, C.E.
登録日2004-04-21
公開日2004-07-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Relationships and Cellular Tropism of Staphylococcal Superantigen-Like Proteins
Infect.Immun., 72, 2004
2YHJ
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Clostridium perfringens Enterotoxin at 4.0 Angstrom Resolution
分子名称: HEAT-LABILE ENTEROTOXIN B CHAIN
著者Briggs, D.C, Naylor, C.E, Smedley III, J.G, McClane, B.A, Basak, A.K.
登録日2011-05-03
公開日2011-08-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of the Food-Poisoning Clostridium Perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins
J.Mol.Biol., 413, 2011
2XH6
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Clostridium perfringens enterotoxin
分子名称: 1,4-DIETHYLENE DIOXIDE, HEAT-LABILE ENTEROTOXIN B CHAIN, octyl beta-D-glucopyranoside
著者Briggs, D.C, Naylor, C.E, Smedley III, J.G, MCClane, B.A, Basak, A.K.
登録日2010-06-09
公開日2011-04-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structure of the Food-Poisoning Clostridium Perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins
J.Mol.Biol., 413, 2011
1OLP
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Alpha Toxin from Clostridium Absonum
分子名称: ALPHA-TOXIN, CALCIUM ION, ZINC ION
著者Briggs, D.C, Basak, A.K.
登録日2003-08-11
公開日2003-10-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Clostridium Absonum Alpha-Toxin: New Insights Into Clostridial Phospholipase C Substrate Binding and Specificity
J.Mol.Biol., 333, 2003
2WNO
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BU of 2wno by Molmil
X-ray Structure of CUB_C domain from TSG-6
分子名称: CALCIUM ION, COBALT (II) ION, TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN
著者Briggs, D.C, Day, A.J.
登録日2009-07-13
公開日2010-09-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Metal Ion-Dependent Heavy Chain Transfer Activity of Tsg-6 Mediates Assembly of the Cumulus-Oocyte Matrix.
J.Biol.Chem., 290, 2015

 

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