8FMJ
 
 | | Crystal structure of human KRAS in space group R32 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Brenner, R, Landgraf, A, Gonzalez-Gutierrez, G, Bum-Erdene, K, Meroueh, S.O. | | Deposit date: | 2022-12-23 | | Release date: | 2023-11-22 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling.
Biochemistry, 62, 2023
|
|
8FMI
 | | Crystal structure of human KRAS at 1.12 A | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION | | Authors: | Brenner, R, Landgraf, A, Gonzalez-Gutierrez, G, Bum-Erdene, K, Meroueh, S.O. | | Deposit date: | 2022-12-23 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling.
Biochemistry, 62, 2023
|
|
8FMK
 | | Crystal structure of human KRAS with extended switch I loop | | Descriptor: | CHLORIDE ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Brenner, R, Landgraf, A, Gonzalez-Gutierrez, G, Bum-Erdene, K, Meroueh, S.O. | | Deposit date: | 2022-12-23 | | Release date: | 2023-11-22 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling.
Biochemistry, 62, 2023
|
|
9BAJ
 | | Crystal structure of GDP-bound human K-RAS in a covalent complex with aryl sulfonyl fluoride compounds. | | Descriptor: | 3-(dioxo-lambda~6~-sulfanyl)-N-phenylbenzene-1-sulfonamide, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | Authors: | Landgraf, A.D, Brenner, R.J, Ghozayel, M.K, Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S. | | Deposit date: | 2024-04-04 | | Release date: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Small-Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation.
Chemmedchem, 2025
|
|
9BAK
 | | Crystal structure of GDP-bound human K-RAS in a covalent complex with aryl sulfonyl fluoride compounds. | | Descriptor: | 3-[bis(oxidanylidene)-$l^{5}-sulfanyl]-~{N}-pyridazin-3-yl-benzenesulfonamide, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | Authors: | Landgraf, A.D, Brenner, R.J, Ghozayel, M.K, Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S. | | Deposit date: | 2024-04-04 | | Release date: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Small-Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation.
Chemmedchem, 2025
|
|
9BAI
 | | Crystal structure of GDP-bound human K-RAS in a covalent complex with aryl sulfonyl fluoride compounds. | | Descriptor: | 3-[bis(oxidanylidene)-$l^{5}-sulfanyl]-~{N}-pyridin-4-yl-benzenesulfonamide, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | Authors: | Landgraf, A.D, Brenner, R.J, Ghozayel, M.K, Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S. | | Deposit date: | 2024-04-04 | | Release date: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Small-Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation.
Chemmedchem, 2025
|
|
