5UCG
 
 | | Structure of the PP2C Phosphatase Domain and a Fragment of the Regulatory Domain of the Cell Fate Determinant SpoIIE from Bacillus Subtilis | | 分子名称: | Stage II sporulation protein E | | 著者 | Bradshaw, N, Levdikov, V, Zimanyi, C, Gaudet, R, Wilkinson, A, Losick, R. | | 登録日 | 2016-12-22 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.906 Å) | | 主引用文献 | A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.
Elife, 6, 2017
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8FWI
 | | Structure of dodecameric KaiC-RS-S413E/S414E solved by cryo-EM | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein KaiC, ... | | 著者 | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | 登録日 | 2023-01-22 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8FWJ
 | | Structure of dodecameric KaiC-RS-S413E/S414E complexed with KaiB-RS solved by cryo-EM | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein KaiB, ... | | 著者 | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | 登録日 | 2023-01-22 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8DB3
 | | Crystal structure of KaiC with truncated C-terminal coiled-coil domain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC | | 著者 | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | 登録日 | 2022-06-14 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8DBA
 | | Crystal structure of dodecameric KaiC | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC, MAGNESIUM ION | | 著者 | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | 登録日 | 2022-06-14 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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9CJ1
 | | Dual phosphorylated human p38 alpha bound to nilotinib | | 分子名称: | 1,2-ETHANEDIOL, Mitogen-activated protein kinase 14, Nilotinib | | 著者 | Stadnicki, E.J, Ludewig, H, Prem Kumar, R, Kern, D, Bradshaw, N. | | 登録日 | 2024-07-05 | | 公開日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Dual-Action Kinase Inhibitors Influence p38 alpha MAP Kinase Dephosphorylation.
Biorxiv, 2024
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9CJ3
 | | Dual phosphorylated human p38 alpha bound to pexmetinib | | 分子名称: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, DIMETHYL SULFOXIDE, ... | | 著者 | Stadnicki, E.J, Ludewig, H, Prem Kumar, R, Kern, D, Bradshaw, N. | | 登録日 | 2024-07-05 | | 公開日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Dual-Action Kinase Inhibitors Influence p38 alpha MAP Kinase Dephosphorylation.
Biorxiv, 2024
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9CJ2
 | | Dual phosphorylated human p38 alpha | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Mitogen-activated protein kinase 14 | | 著者 | Stadnicki, E.J, Ludewig, H, Prem Kumar, R, Kern, D, Bradshaw, N. | | 登録日 | 2024-07-05 | | 公開日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Dual-Action Kinase Inhibitors Influence p38 alpha MAP Kinase Dephosphorylation.
Biorxiv, 2024
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9CJ4
 | | Dual phosphorylated human p38 alpha bound to BIRB796 | | 分子名称: | 1,2-ETHANEDIOL, 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Stadnicki, E.J, Ludewig, H, Prem Kumar, R, Kern, D, Bradshaw, N. | | 登録日 | 2024-07-05 | | 公開日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Dual-Action Kinase Inhibitors Influence p38 alpha MAP Kinase Dephosphorylation.
Biorxiv, 2024
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9CJ5
 | | Unphosphorylated human p38 alpha bound to pexmetinib | | 分子名称: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, Mitogen-activated protein kinase 14, ... | | 著者 | Stadnicki, E.J, Ludewig, H, Prem Kumar, R, Kern, D, Bradshaw, N. | | 登録日 | 2024-07-05 | | 公開日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Dual-Action Kinase Inhibitors Influence p38 alpha MAP Kinase Dephosphorylation.
Biorxiv, 2024
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