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PDB: 130 results
4OW4
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BU of 4ow4 by Molmil
Beta-trefoil designed by folding nucleus symmetric expansion ("Phifoil")
Descriptor: Beta-terfoil designed by folding nucleus symmetric expansion ("Phifoil"), SULFATE ION
Authors:Blaber, M, Longo, L.M.
Deposit date:2014-01-31
Release date:2014-12-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Evolution and design of protein structure by folding nucleus symmetric expansion.
Structure, 22, 2014
3HOM
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BU of 3hom by Molmil
Crystal structure of oxidized A66C mutant of Human acidic fibroblast growth factor
Descriptor: Acidic fibroblast growth factor, FORMIC ACID, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2009-06-02
Release date:2009-10-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
3L64
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BU of 3l64 by Molmil
T4 Lysozyme S44E/WT*
Descriptor: BETA-MERCAPTOETHANOL, Lysozyme
Authors:Blaber, M, Zhang, X.-J, Lindstrom, J.D, Pepiot, S.D, Baase, W.A, Matthews, B.W.
Deposit date:2009-12-23
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Determination of alpha-helix propensity within the context of a folded protein. Sites 44 and 131 in bacteriophage T4 lysozyme.
J.Mol.Biol., 235, 1994
4D8H
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BU of 4d8h by Molmil
Crystal structure of Symfoil-4P/PV2: de novo designed beta-trefoil architecture with symmetric primary structure, primitive version 2 (6xLeu / PV1)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo protein
Authors:Blaber, M, Longo, L.
Deposit date:2012-01-10
Release date:2013-01-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F34
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BU of 4f34 by Molmil
Symfoil-4V synthetic protein with T30E/T72E/T116E mutations, and delta His tag
Descriptor: de novo protein Symfoil-4V
Authors:Blaber, M, Xia, X.
Deposit date:2012-05-08
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Symfoil-4V synthetic protein with T30E/T72E/T116E mutations, and delta His tag
TO BE PUBLISHED
3Q7W
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BU of 3q7w by Molmil
Crystal structure of Symfoil-4P/PV1: de novo designed beta-trefoil architecture with symmetric primary structure, primitive version 1
Descriptor: SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure
Authors:Blaber, M, Lee, J.
Deposit date:2011-01-05
Release date:2012-01-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
3Q7Y
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BU of 3q7y by Molmil
Crystal structure of K15R/E18D/Y22W/H41G/F44W/E51D/E53P/K57R/E60D/Y64W/H82G/F85W/E90D/E94P/K98R/E101D/Y108W/H129G/F132W/E137D Symfoil-4P: de novo designed beta-trefoil architecture with symmetric primary structure
Descriptor: De novo designed beta-trefoil architecture with symmetric primary structure
Authors:Blaber, M, Lee, J.
Deposit date:2011-01-05
Release date:2012-01-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
3SNV
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BU of 3snv by Molmil
Crystal structure of Symfoil-4T Permutation #1: de novo designed beta-trefoil architecture with symmetric primary structure
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, Symfoil-4T/Permutation #1 synthetic protein
Authors:Blaber, M, Longo, L, Lee, J.
Deposit date:2011-06-29
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Folding pathway redundancy in symmetric protein architecture
To be Published
3Q7X
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BU of 3q7x by Molmil
Crystal structure of Symfoil-4P/PV1: de novo designed beta-trefoil architecture with symmetric primary structure, primitive version 1
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure
Authors:Blaber, M, Lee, J.
Deposit date:2011-01-05
Release date:2012-01-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
3HAL
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BU of 3hal by Molmil
Crystal structure of Rabbit acidic fibroblast growth factor
Descriptor: CHLORIDE ION, Fibroblast growth factor 1 isoform 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2009-05-01
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structure and biophysical properties of rabbit fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3P6I
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BU of 3p6i by Molmil
Crystal structure of Symfoil-4T Permutation #2: de novo designed beta-trefoil architecture with symmetric primary structure
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure
Authors:Blaber, M, Lee, J.
Deposit date:2010-10-11
Release date:2011-10-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Permutations study of de novo designed symmetric beta-trefoil architecture
To be Published
3P6J
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BU of 3p6j by Molmil
Crystal structure of Symfoil-4T Permutation #3: de novo designed beta-trefoil architecture with symmetric primary structure
Descriptor: de novo designed beta-trefoil architecture with symmetric primary structure
Authors:Blaber, M, Lee, J.
Deposit date:2010-10-11
Release date:2011-10-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Permutations study of de novo designed symmetric beta-trefoil architecture
To be Published
4QAL
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BU of 4qal by Molmil
Crystal structure of C117A mutant of human acidic fibroblast growth factor
Descriptor: CITRATE ANION, Fibroblast growth factor 1
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-05
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4Q9G
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BU of 4q9g by Molmil
Crystal structure of K12V/C16S/C117V/P134V mutant of human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Fibroblast growth factor 1, PHOSPHATE ION
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-01
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.554 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4QBC
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BU of 4qbc by Molmil
Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium formate buffer
Descriptor: FORMIC ACID, Fibroblast growth factor 1, SULFATE ION
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-07
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.519 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4QBV
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BU of 4qbv by Molmil
Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium citrate buffer
Descriptor: CITRATE ANION, Fibroblast growth factor 1
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-08
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4QC4
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BU of 4qc4 by Molmil
Crystal structure of C117S mutant of human acidic fibroblast growth factor
Descriptor: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE, ...
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-09
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4Q9P
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BU of 4q9p by Molmil
Crystal structure of C16T/K12V/C117V/P134V mutant of human acidic fibroblast growth factor
Descriptor: Fibroblast growth factor 1
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-01
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4QO3
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BU of 4qo3 by Molmil
Crystal structure of C16S/N18S/K12V/C117V/P134V mutant of human acidic fibroblast growth factor
Descriptor: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE
Authors:Blaber, M, Xia, X.
Deposit date:2014-06-19
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Thermodynamics of Cysteine Substitution Suggest Unique Structural Role for Cysteine in Proteins
To be Published
3FJK
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BU of 3fjk by Molmil
Crystal structure of A66C mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
3FJB
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BU of 3fjb by Molmil
Crystal structure of V31I mutant of Human acidic fibroblast growth factor
Descriptor: Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
3FJI
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BU of 3fji by Molmil
Crystal structure of K12V/C83I/C117V mutant of Human acidic fibroblast growth factor
Descriptor: Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
3FJA
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BU of 3fja by Molmil
Crystal structure of F132W mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
221L
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BU of 221l by Molmil
THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1993-05-28
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Biochemistry, 32, 1993
3FGM
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BU of 3fgm by Molmil
Crystal structure of L44F/C83T/C117V/F132W mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-06
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009

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