7MI6
| Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound, Model 1 | Descriptor: | (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ... | Authors: | Santarossa, C.C, Urnavicius, L, Coudray, N, Ekeirt, D.C, Bhabha, G, Kapoor, T.M. | Deposit date: | 2021-04-16 | Release date: | 2021-05-26 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
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8F6R
| CryoEM structure of designed modular protein oligomer C6-79 | Descriptor: | De novo designed oligomeric protein C6-79 | Authors: | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | Deposit date: | 2022-11-17 | Release date: | 2023-11-29 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies Cell(Cambridge,Mass.), 187, 2024
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7UDJ
| Crystal structure of designed helical repeat protein RPB_PEW3_R4 bound to PAWx4 peptide | Descriptor: | 4xPAW peptide, De novo designed helical repeat protein RPB_PEW3_R4 | Authors: | Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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6V0F
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 4 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0H
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 6 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0C
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 1 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0E
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 3 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0J
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 8 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0G
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 5 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0I
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 7 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6VCI
| Lipophilic envelope-spanning tunnel protein (LetB), domains MCE2-MCE3 | Descriptor: | Lipophilic envelope-spanning tunnel protein LetB | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-12-21 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0D
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 2 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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7UE2
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7UDK
| Crystal structure of designed helical repeat protein RPB_LRP2_R4 bound to LRPx4 peptide | Descriptor: | 4xLRP, Designed helical repeat protein (DHR) RPB_LRP2_R4 | Authors: | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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7UDO
| Crystal structure of designed helical repeat protein RPB_LRP2_R4 (proteolysis fragment?), forming pseudopolymeric filaments | Descriptor: | 1,2-ETHANEDIOL, Designed helical repeat protein (DHR) RPB_LRP2_R4, PHOSPHATE ION | Authors: | Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D.C. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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7UDL
| Crystal structure of designed helical repeat protein RPB_PLP1_R6 bound to PLPx6 peptide | Descriptor: | 1,2-ETHANEDIOL, 6xPLP Peptide, Designed helical repeat protein (DHR) RPB_PLP1_R6 | Authors: | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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7UDN
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7UDM
| Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 1 (with peptide) | Descriptor: | 6xPLP, Designed helical repeat protein (DHR) RPB_PLP1_R6 | Authors: | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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4KJK
| Room Temperature WT DHFR | Descriptor: | CALCIUM ION, Dihydrofolate reductase, FOLIC ACID, ... | Authors: | van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S. | Deposit date: | 2013-05-03 | Release date: | 2013-08-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.351 Å) | Cite: | Automated identification of functional dynamic contact networks from X-ray crystallography. Nat.Methods, 10, 2013
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4KJL
| Room Temperature N23PPS148A DHFR | Descriptor: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S. | Deposit date: | 2013-05-03 | Release date: | 2013-08-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Automated identification of functional dynamic contact networks from X-ray crystallography. Nat.Methods, 10, 2013
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4KJJ
| Cryogenic WT DHFR | Descriptor: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S. | Deposit date: | 2013-05-03 | Release date: | 2013-08-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Automated identification of functional dynamic contact networks from X-ray crystallography. Nat.Methods, 10, 2013
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