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PDB: 8 results

1KVL
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X-ray Crystal Structure of AmpC S64G Mutant beta-Lactamase in Complex with Substrate and Product Forms of Cephalothin
Descriptor: 2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, 2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase, ...
Authors:Beadle, B.M, Trehan, I, Focia, P.J, Shoichet, B.K.
Deposit date:2002-01-27
Release date:2002-03-13
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural milestones in the reaction pathway of an amide hydrolase: substrate, acyl, and product complexes of cephalothin with AmpC beta-lactamase.
Structure, 10, 2002
1L0G
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BU of 1l0g by Molmil
X-ray Crystal Structure of AmpC S64G Mutant beta-Lactamase
Descriptor: PHOSPHATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-02-09
Release date:2002-08-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural bases of stability-function tradeoffs in enzymes.
J.Mol.Biol., 321, 2002
1LL5
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X-ray crystal structure of AmpC WT beta-lactamase in complex with covalently bound imipenem
Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-04-26
Release date:2002-11-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Imipenem Inhibition of Class C beta-lactamases
ANTIMICROB.AGENTS CHEMOTHER., 46, 2002
1L0D
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BU of 1l0d by Molmil
X-ray Crystal Structure of AmpC S64D Mutant beta-Lactamase
Descriptor: PHOSPHATE ION, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-02-09
Release date:2002-08-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural bases of stability-function tradeoffs in enzymes.
J.Mol.Biol., 321, 2002
1L0F
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BU of 1l0f by Molmil
X-ray Crystal Structure of AmpC N152H Mutant beta-Lactamase
Descriptor: PHOSPHATE ION, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-02-09
Release date:2002-08-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural bases of stability-function tradeoffs in enzymes.
J.Mol.Biol., 321, 2002
1L0E
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BU of 1l0e by Molmil
X-ray Crystal Structure of AmpC K67Q Mutant beta-Lactamase
Descriptor: PHOSPHATE ION, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-02-09
Release date:2002-08-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural bases of stability-function tradeoffs in enzymes.
J.Mol.Biol., 321, 2002
1KVM
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BU of 1kvm by Molmil
X-ray Crystal Structure of AmpC WT beta-Lactamase in Complex with Covalently Bound Cephalothin
Descriptor: 5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, PHOSPHATE ION, beta-lactamase
Authors:Beadle, B.M, Trehan, I, Focia, P.J, Shoichet, B.K.
Deposit date:2002-01-27
Release date:2002-03-13
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural milestones in the reaction pathway of an amide hydrolase: substrate, acyl, and product complexes of cephalothin with AmpC beta-lactamase.
Structure, 10, 2002
1I5Q
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CRYSTAL STRUCTURE OF THE E. COLI AMPC BETA-LACTAMASE MUTANT N152A COVALENTLY ACYLATED WITH THE INHIBITORY BETA-LACTAM, MOXALACTAM
Descriptor: (2R)-2-[(1R)-1-{[(2S)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}-1-methoxy-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-oxazine-4-carboxylic acid, BETA-LACTAMASE
Authors:Trehan, I, Beadle, B.M, Shoichet, B.K.
Deposit date:2001-02-28
Release date:2001-06-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Inhibition of AmpC beta-lactamase through a destabilizing interaction in the active site.
Biochemistry, 40, 2001

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