Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 455 results

3ZVA
DownloadVisualize
BU of 3zva by Molmil
3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 75
Descriptor: 3C PROTEASE, ETHYL (4R)-4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE
Authors:Tan, J, Perbandt, M, Mesters, J.R, Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3ZVC
DownloadVisualize
BU of 3zvc by Molmil
3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 82
Descriptor: 3C PROTEASE, ETHYL (5S,8S,11R)-8-BENZYL-5-(3-TERT-BUTOXY-3-OXOPROPYL)-3,6,9-TRIOXO-11-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}-1-PHENYL-2-OXA-4,7,10-TRIAZATETRADECAN-14-OATE
Authors:Tan, J, Perbandt, M, Mesters, J.R, Hilgenfeld, R.
Deposit date:2011-07-24
Release date:2012-08-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
3CVB
DownloadVisualize
BU of 3cvb by Molmil
Regulation of Protein Function: Crystal Packing Interfaces and Conformational Dimerization
Descriptor: COPPER (I) ION, Plastocyanin
Authors:Crowley, P.B, Matias, P.M, Mi, H, Firbank, S.J, Banfield, M.J, Dennison, C.
Deposit date:2008-04-18
Release date:2008-07-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Regulation of protein function: crystal packing interfaces and conformational dimerization.
Biochemistry, 47, 2008
6C8G
DownloadVisualize
BU of 6c8g by Molmil
Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of barium
Descriptor: BARIUM ION, Transient receptor potential cation channel, subfamily V, ...
Authors:Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P.
Deposit date:2018-01-24
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6.31 Å)
Cite:Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Nat. Struct. Mol. Biol., 25, 2018
3CVC
DownloadVisualize
BU of 3cvc by Molmil
Regulation of Protein Function: Crystal Packing Interfaces and Conformational Dimerization
Descriptor: COPPER (II) ION, MAGNESIUM ION, Plastocyanin
Authors:Crowley, P.B, Matias, P.M, Mi, H, Firbank, S.J, Banfield, M.J, Dennison, C.
Deposit date:2008-04-18
Release date:2008-07-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Regulation of protein function: crystal packing interfaces and conformational dimerization.
Biochemistry, 47, 2008
3CVD
DownloadVisualize
BU of 3cvd by Molmil
Regulation of Protein Function: Crystal Packing Interfaces and Conformational Dimerization
Descriptor: COPPER (I) ION, Plastocyanin, ZINC ION
Authors:Crowley, P.B, Matias, P.M, Mi, H, Firbank, S.J, Banfield, M.J, Dennison, C.
Deposit date:2008-04-18
Release date:2008-07-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Regulation of protein function: crystal packing interfaces and conformational dimerization.
Biochemistry, 47, 2008
6C8H
DownloadVisualize
BU of 6c8h by Molmil
Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of gadolinium
Descriptor: GADOLINIUM ATOM, Transient receptor potential cation channel, subfamily V, ...
Authors:Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P.
Deposit date:2018-01-24
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Nat. Struct. Mol. Biol., 25, 2018
6C8F
DownloadVisualize
BU of 6c8f by Molmil
Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of cesium
Descriptor: CESIUM ION, Transient receptor potential cation channel, subfamily V, ...
Authors:Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P.
Deposit date:2018-01-24
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Nat. Struct. Mol. Biol., 25, 2018
3U8E
DownloadVisualize
BU of 3u8e by Molmil
Crystal Structure of Cysteine Protease from Bulbs of Crocus sativus at 1.3 A Resolution
Descriptor: GLYCEROL, Papain-like Cysteine Protease, SODIUM ION, ...
Authors:Iqbal, S, Akrem, A, Buck, F, Perbandt, M, Banumathi, S, Betzel, C.
Deposit date:2011-10-17
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Crystal Structure of A Papain-like Cysteine Protease from Bulbs of Crocus sativum at 1.3 A resolution
To be Published
8FWA
DownloadVisualize
BU of 8fwa by Molmil
Phycocyanin structure from a modular droplet injector for serial femtosecond crystallography
Descriptor: C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN, ...
Authors:Botha, S, Doppler, D.L, Sonker, M, Egatz-Gomez, A, Grieco, A, Zaare, S, Jernigan, R, Meza-Aguilar, J.D, Rabbani, M.T, Manna, A, Alvarez, R, Karpos, K, Cruz Villarreal, J, Nelson, G, Ketawala, G.K, Pey, A.L, Ruiz-Fresneda, M.A, Pacheco-Garcia, J.L, Nazari, R, Sierra, R, Hunter, M.S, Batyuk, A, Kupitz, C.J, Sublett, R.E, Lisova, S, Mariani, V, Boutet, S, Fromme, R, Grant, T.D, Fromme, P, Kirian, R.A, Martin-Garcia, J.M, Ros, A.
Deposit date:2023-01-20
Release date:2023-06-28
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme.
Lab Chip, 23, 2023
2VTX
DownloadVisualize
BU of 2vtx by Molmil
ACTIVATION OF NUCLEOPLASMIN, AN OLIGOMERIC HISTONE CHAPERONE, CHALLENGES ITS STABILITY
Descriptor: NPM-A PROTEIN
Authors:Taneva, S.G, Munoz, I.G, Franco, G, Falces, J, Arregi, I, Muga, A, Montoya, G, Urbaneja, M.A, Banuelos, S.
Deposit date:2008-05-16
Release date:2008-12-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Activation of Nucleoplasmin, an Oligomeric Histone Chaperone, Challenges its Stability.
Biochemistry, 47, 2008
2VQA
DownloadVisualize
BU of 2vqa by Molmil
Protein-folding location can regulate Mn versus Cu- or Zn-binding. Crystal Structure of MncA.
Descriptor: ACETATE ION, MANGANESE (II) ION, SLL1358 PROTEIN
Authors:Tottey, S, Waldron, K.J, Firbank, S.J, Reale, B, Bessant, C, Sato, K, Gray, J, Banfield, M.J, Dennison, C, Robinson, N.J.
Deposit date:2008-03-12
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Protein-Folding Location Can Regulate Manganese-Binding Versus Copper- or Zinc-Binding.
Nature, 455, 2008
4BDJ
DownloadVisualize
BU of 4bdj by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 3-cyclopropyl-4-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine, CHECKPOINT KINASE 2, NITRATE ION
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4BDK
DownloadVisualize
BU of 4bdk by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 1,2-ETHANEDIOL, CHECKPOINT KINASE 2, N-[(4-methoxyphenyl)methyl]quinoxaline-6-carboxamide, ...
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4BDI
DownloadVisualize
BU of 4bdi by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 1,2-ETHANEDIOL, 1-acetyl-N-(5-methylpyridin-2-yl)piperidine-4-carboxamide, CHLORIDE ION, ...
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4BDB
DownloadVisualize
BU of 4bdb by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 1,2-ETHANEDIOL, 4-[(E)-C-methyl-N-oxidanyl-carbonimidoyl]benzene-1,3-diol, NITRATE ION, ...
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4BDE
DownloadVisualize
BU of 4bde by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 1,2-ETHANEDIOL, 6-METHYLQUINAZOLIN-4-AMINE, NITRATE ION, ...
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4BDH
DownloadVisualize
BU of 4bdh by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 1,2-ETHANEDIOL, 3-METHYL-4-(THIOPHEN-2-YL)-1H-PYRAZOL-5-AMINE, CHLORIDE ION, ...
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4BDG
DownloadVisualize
BU of 4bdg by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 1,2-ETHANEDIOL, 3-(PYRIDIN-3-YL)-1H-PYRAZOL-5-AMINE, CHLORIDE ION, ...
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4BDA
DownloadVisualize
BU of 4bda by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 1,2-ETHANEDIOL, 3,4-dihydro[1,2,4]triazolo[1,5-a][3,1]benzimidazol-9-ium, CHLORIDE ION, ...
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4BDC
DownloadVisualize
BU of 4bdc by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, N-(furan-2-ylmethyl)quinoxaline-6-carboxamide, ...
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4BDD
DownloadVisualize
BU of 4bdd by Molmil
Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Descriptor: 1,2-ETHANEDIOL, 1-(TERT-BUTYL)-3-(QUINOXALIN-6-YL)UREA, NITRATE ION, ...
Authors:Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M.
Deposit date:2012-10-05
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
4A9U
DownloadVisualize
BU of 4a9u by Molmil
CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR
Descriptor: 1,2-ETHANEDIOL, 2-{4-[(1-BENZYLPIPERIDIN-4-YL)METHOXY]PHENYL}-1H-BENZIMIDAZOLE-6-CARBOXAMIDE, CHLORIDE ION, ...
Authors:Matijssen, C, Silva-Santisteban, M.C, Westwood, I.M, Siddique, S, Choi, V, Sheldrake, P, van Montfort, R.L.M, Blagg, J.
Deposit date:2011-11-28
Release date:2012-10-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Benzimidazole Inhibitors of the Protein Kinase Chk2: Clarification of the Binding Mode by Flexible Side Chain Docking and Protein-Ligand Crystallography
Bioorg.Med.Chem., 20, 2012
2XMV
DownloadVisualize
BU of 2xmv by Molmil
Copper chaperone Atx1 from Synechocystis PCC6803 (Cu1, trimeric form, His61Tyr mutant)
Descriptor: COPPER (I) ION, SSR2857 PROTEIN
Authors:Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C.
Deposit date:2010-07-29
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Visualizing the Metal-Binding Versatility of Copper Trafficking Sites .
Biochemistry, 49, 2010
6NAQ
DownloadVisualize
BU of 6naq by Molmil
Crystal structure of Neisseria meningitidis ClpP protease in Apo form
Descriptor: ATP-dependent Clp protease proteolytic subunit, POTASSIUM ION
Authors:Houry, W.A, Mabanglo, M.F, Pai, E.F, Eger, B.T, Bryson, S.
Deposit date:2018-12-06
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.022 Å)
Cite:ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon